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Untreated and overweight children may have worse asthma symptoms

Asthma affects almost 1 in 10 children in the U.S. and is a leading cause of emergency room visits and hospitalizations in preschoolers. According to new research from Duke Health and collaborators, symptoms may be worse for children ages 2 to 5 who are overweight.

19 Dec 2017

Zinc present in semen determines male fertility, study shows

Trace levels of zinc present in semen is a vital determinant of male fertility, a recent study in Bangladesh capital Dhaka concludes.

19 Dec 2017

Researchers team up to identify vulnerabilities of lethal parasite

An estimated 100 million people around the world are infected with Strongyloides stercoralis, a parasitic nematode, yet it's likely that many don't know it.

15 Dec 2017

Steroid study provides new insights into medicines' side effects

Fresh insights into key hormones found in commonly prescribed medicines have been discovered, providing further understanding of the medicines' side effects.

13 Dec 2017

UT Southwestern researchers identify potential approach to suppress lethal parasitic infections

UT Southwestern Medical Center researchers have identified a chemical that suppresses the lethal form of a parasitic infection caused by roundworms that affects up to 100 million people and usually causes only mild symptoms.

5 Dec 2017

Direct switch of COPD patients from Seretide to Novartis' Ultibro Breezhaler improves lung function

Novartis today announced positive results from the FLASH study examining the safety and efficacy of directly switching chronic obstructive pulmonary disease (COPD) patients from Seretide (salmeterol/fluticasone) 50/500 mcg to Ultibro Breezhaler (indacaterol/glycopyrronium) 110/50 mcg.

27 Nov 2017

Decompression surgery may offer no additional benefit for people with shoulder impingement

Decompression surgery does not reduce shoulder pain any more than placebo surgery for people with shoulder impingement – when the tendon rubs and catches in the joint, according to the first placebo-controlled trial in shoulder surgery published in The Lancet.

22 Nov 2017

AstraZeneca’s new precision biologic gets FDA approval to treat severe eosinophilic asthma

AstraZeneca and its global biologics research and development arm, MedImmune, today announced that the US Food and Drug Administration has approved FASENRA (benralizumab) for the add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype.

14 Nov 2017

Chronic preconception exposure to genistein may adversely affect female fertility, mice study finds

Exposure to the phytoestrogen genistein prior to conception may adversely affect female fertility and pregnancy outcomes, depending on the dosage and duration of exposure, a new study in mice suggests.

14 Nov 2017

Higher hair cortisol levels during pregnancy could be indicator of postpartum depression

Researchers from the University of Granada, who belong to the Brain, Mind and Behavior Research Center and the Faculty of Psychology, have proven that cortisol levels (a steroid hormone secreted as a response to stress) present in the hair of pregnant women during the first or third trimesters of pregnancy may indicate which of them are more likely to suffer postpartum depression.

14 Nov 2017

Researchers find low levels of neuroactive steroid in both obese and anorexic women

Women at opposite extremes of the weight spectrum have low levels of the neuroactive steroid allopregnanolone, according to new research published in the journal Neuropsychopharmacology.

10 Nov 2017

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

An analysis of the medical records of patients treated at Massachusetts General Hospital (MGH) for an often-mysterious condition involving damage to small nerve fibers supports the hypothesis that some cases are caused by autoimmune disease and also identifies the first effective treatment option.

9 Nov 2017

CRFA better than steroid injection for managing pain from knee osteoarthritis

For patients with osteoarthritis of the knee, a minimally invasive procedure called cooled radiofrequency ablation provides better pain reduction and functional improvement compared to steroid injection of the knee, concludes a study in Regional Anesthesia & Pain Medicine, published by Wolters Kluwer.

2 Nov 2017

Hospitals need to improve emergency care practices for treating older cancer patients, study reveals

A new study finds that patients with cancer, especially those aged 75 or older, are more likely to be admitted to the hospital – and less likely to be observed and released home – than patients without cancer.

25 Oct 2017

Scientists unravel mechanism that links gut bacteria to hypertension

One in three American adults suffers from high blood pressure, or hypertension. The disease can be passed down in families, and certain lifestyle factors such as smoking, high-sodium diets, and stress can increase the risk.

3 Oct 2017

Flat-fee primary care helps fill niche for Texas’ uninsured

Darrell Kenyon had been punting for years on various medical issues — fatigue, headaches, mood swings. The 43-year-old uninsured carpenter was particularly worried about his blood pressure, which ran high when he checked it at the grocery store. Then he heard about a different type of physician practice, one that provided regular primary care for a monthly fee.

3 Oct 2017

Estrogen acts as upstream regulator for energy metabolism and muscle cell viability, study finds

According to a research conducted at the University of Jyväskylä, estrogen acts as a regulator of muscle energy metabolism and muscle cell viability. Menopause leads to the cessation of ovarian estrogen production concurrent to the deterioration of muscle function.

3 Oct 2017

Advanced technique could pave way for cascade of new steroidal therapeutics

Researchers at Dartmouth College have developed a technique to produce synthetic steroids that could pave the way for a cascade of new drug discoveries. The process, published in the journal Nature Chemistry, facilitates access to rare, mirror-image isomers of naturally occurring steroid structures.

26 Sep 2017

Steroid hormones could provide new insight into age-related bone loss

A group of steroid hormones could provide new insight into the bone loss and deterioration that occurs with aging, researchers at the Medical College of Georgia at Augusta University report.

15 Sep 2017

Component of fire ant venom shows promise as a psoriasis treatment

In a new study involving laboratory mice, researchers have found that solenopsin and similar compounds could be beneficial for psoriasis.

11 Sep 2017

Steroid News and Research

Untreated and overweight children may have worse asthma symptoms

Zinc present in semen determines male fertility, study shows

Researchers team up to identify vulnerabilities of lethal parasite

Steroid study provides new insights into medicines' side effects

UT Southwestern researchers identify potential approach to suppress lethal parasitic infections

Direct switch of COPD patients from Seretide to Novartis' Ultibro Breezhaler improves lung function

Decompression surgery may offer no additional benefit for people with shoulder impingement

AstraZeneca’s new precision biologic gets FDA approval to treat severe eosinophilic asthma

Chronic preconception exposure to genistein may adversely affect female fertility, mice study finds

Higher hair cortisol levels during pregnancy could be indicator of postpartum depression

Researchers find low levels of neuroactive steroid in both obese and anorexic women

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

CRFA better than steroid injection for managing pain from knee osteoarthritis

Hospitals need to improve emergency care practices for treating older cancer patients, study reveals

Scientists unravel mechanism that links gut bacteria to hypertension

Flat-fee primary care helps fill niche for Texas’ uninsured

Estrogen acts as upstream regulator for energy metabolism and muscle cell viability, study finds

Advanced technique could pave way for cascade of new steroidal therapeutics

Steroid hormones could provide new insight into age-related bone loss

Component of fire ant venom shows promise as a psoriasis treatment

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