Kidney News and Research

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Location-dependent pattern in cilia length in mouse nasal cavity affects sensitivity to odors

Like the hairs they resemble, cilia come in all lengths, from short to long. But unlike the hair on our heads, the length of sensory cilia on nerve cells in our noses is of far more than merely cosmetic significance. A team of researchers from the Perelman School of Medicine at the University of Pennsylvania found a location-dependent pattern in cilia length in the mouse nasal cavity that affects sensitivity to odors.

14 Sep 2015

Study backs more aggressive blood pressure treatment, says ACC President Kim Allan Williams

A statement from American College of Cardiology President Kim Allan Williams Sr., M.D., FACC, regarding the National Institutes of Health stopping the SPRINT trial early after demonstrating the positive benefits of lower blood pressure control targets.

14 Sep 2015

UT Southwestern researchers part of study that shows effectiveness of intensive blood pressure management

More intensive management of high blood pressure, below a commonly recommended blood pressure target, significantly reduces rates of cardiovascular disease, and lowers risk of death in a group of adults 50 years and older with high blood pressure, a National Institutes of Health study involving UT Southwestern Medical Center researchers shows.

14 Sep 2015

Surgeons participate in record-setting day of organ transplantation at Baylor University Medical Center

One week ago, surgical teams took part in a record-setting day of organ transplantation at Baylor University Medical Center at Dallas. Surgeons on the medical staff performed nine organ transplants on seven patients in one calendar day.

11 Sep 2015

New technique could improve selectivity of cancer drugs, decrease unwanted side effects in future

A class of therapeutic drugs known as protein kinase inhibitors has in the past decade become a powerful weapon in the fight against various life-threatening diseases, including certain types of leukemia, lung cancer, kidney cancer and squamous cell cancer of the head and neck.

11 Sep 2015

Researchers find key cellular enzyme that could be effective drug target for urologic cancer cells

Researchers at the SUNY Upstate Medical University have found that a key cellular enzyme, c-Abl, could be an effective drug target in cancer cells for urologic cancers, such as prostate and kidney.

11 Sep 2015

Study may help scientists to better understand complications caused by drug therapy in kidney transplant patients

New research will help scientists and medical professionals to better understand the long-term complications caused by an immunosuppressant drug used to treat thousands of kidney transplant patients.

11 Sep 2015

High blood pressure, smoking, and poor dietary habits are greatest risk factors for death

A huge international study of global causes of death has revealed that since 1990, there has been a profound change in risk factors for death.

11 Sep 2015

ICU-related mortality may explain variations in cancer outcomes

A Scottish population-based study has characterised the incidence of critical illness resulting in admission to an intensive care unit during the first 2 years after a cancer diagnosis.

9 Sep 2015

Diabetes often goes undiagnosed in more than half of Asian Americans

More than half of Asian Americans and nearly half of Hispanic Americans with diabetes are undiagnosed, according to researchers from the National Institutes of Health and the Centers for Disease Control and Prevention.

9 Sep 2015

DCR launches Biospecimen Research Grant Program

DaVita Clinical Research, a specialty contract research organization with services spanning a broad spectrum of drug and device development, announced today its Biospecimen Research Grant Program (BioReG), a grant program to award clinical-trial-quality biospecimens and annotated de-identified data to academic medical centers involved in kidney research.

8 Sep 2015

Mitochondrial Pyruvate Carrier could potentially be a new drug target to treat diabetes

High blood sugar is a defining characteristic of Type 2 diabetes and the cause of many of the condition's complications, including kidney failure, heart disease, and blindness. Most diabetes medications aim to maintain normal blood sugar (glucose) levels and prevent high blood sugar by controlling insulin.

3 Sep 2015

TMIGD1 protein could be a novel target for restoring kidney function from kidney disease

A new discovery by Boston University School of Medicine (BUSM) researchers may change how kidney disease is treated in the future.

3 Sep 2015

Amgen announces MAA submission to EMA for novel calcimimetic agent etelcalcetide

Amgen today announced the submission of a Marketing Authorization Application (MAA) to the European Medicines Agency via the centralized procedure for etelcalcetide (formerly AMG 416) for the treatment of secondary hyperparathyroidism (SHPT) in adult patients with chronic kidney disease (CKD) on hemodialysis therapy. If approved, etelcalcetide will be the first calcimimetic agent that can be administered intravenously.

3 Sep 2015

UC San Diego-led research team awarded $1.89 million to carry out research on leptospirosis

An international research team, headed by Joseph Vinetz, MD, professor of medicine at University of California, San Diego School of Medicine and director of the UC San Diego Center for Tropical Medicine and Travelers Health, has been awarded a 5-year, $1.89 million cooperative agreement to carry out translational research studies of leptospirosis, an infectious and sometimes fatal bacterial disease endemic in much of the world.

2 Sep 2015

New NIH grants support research that combines DNA sequence information and electronic medical records

A dozen awards from the National Institutes of Health will support research that incorporates DNA sequence information into electronic medical records. The goal of research conducted by the Electronic Medical Records and Genomics (eMERGE) network is to better understand the genomic basis of disease and to tailor medical care to individual patients based on their genomic differences.

2 Sep 2015

Finerenone drug improves albuminuria among patients with diabetes and kidney disease

Among patients with diabetes and kidney disease, most receiving an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker, the addition of the medication finerenone compared with placebo resulted in improvement in albuminuria (the presence of excessive protein [chiefly albumin] in the urine), according to a study in the September 1 issue of JAMA.

2 Sep 2015

Finerenone effective in heart failure patients with diabetes and/or chronic kidney disease

In heart failure patients with diabetes and/or chronic kidney disease, a new, non-steroidal mineralocorticoid receptor antagonist (MRA) called finerenone was no more effective than the currently approved MRA eplerenone in reducing the heart failure biomarker N-terminal pro-B-type natriuretic peptide [NT-proBNP].

1 Sep 2015

GARFIELD-AF Registry: All-cause death is most frequent major event in newly diagnosed AF patients

The first-ever two-year outcomes from the Global Anticoagulant Registry in the Field - Atrial Fibrillation (GARFIELD-AF) showcased at ESC Congress 2015 expose that all-cause death was the most frequent major event in more than 17,000 newly diagnosed AF patients, far exceeding the rate of stroke or major bleeding.

1 Sep 2015

UCSF-led team develops new technique to create tiny models of human tissues

A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These mini-tissues in a dish can be used to study how particular structural features of tissue affect normal growth or go awry in cancer. They could be used for therapeutic drug screening and to help teach researchers how to grow whole human organs.

1 Sep 2015

Kidney News and Research

Location-dependent pattern in cilia length in mouse nasal cavity affects sensitivity to odors

Study backs more aggressive blood pressure treatment, says ACC President Kim Allan Williams

UT Southwestern researchers part of study that shows effectiveness of intensive blood pressure management

Surgeons participate in record-setting day of organ transplantation at Baylor University Medical Center

New technique could improve selectivity of cancer drugs, decrease unwanted side effects in future

Researchers find key cellular enzyme that could be effective drug target for urologic cancer cells

Study may help scientists to better understand complications caused by drug therapy in kidney transplant patients

High blood pressure, smoking, and poor dietary habits are greatest risk factors for death

ICU-related mortality may explain variations in cancer outcomes

Diabetes often goes undiagnosed in more than half of Asian Americans

DCR launches Biospecimen Research Grant Program

Mitochondrial Pyruvate Carrier could potentially be a new drug target to treat diabetes

TMIGD1 protein could be a novel target for restoring kidney function from kidney disease

Amgen announces MAA submission to EMA for novel calcimimetic agent etelcalcetide

UC San Diego-led research team awarded $1.89 million to carry out research on leptospirosis

New NIH grants support research that combines DNA sequence information and electronic medical records

Finerenone drug improves albuminuria among patients with diabetes and kidney disease

Finerenone effective in heart failure patients with diabetes and/or chronic kidney disease

GARFIELD-AF Registry: All-cause death is most frequent major event in newly diagnosed AF patients

UCSF-led team develops new technique to create tiny models of human tissues

Free guide - Everything about renal proximal tubule cells eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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