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Antibody-drug conjugates (ADCs): an interview with Dr Marco Timmers, CSO at Synthon Biopharmaceuticals

ADCs are used for a new type of targeted therapy that consists of a specific anti-cancer antibody or antibody fragment linked to a potent anti-cancer therapeutic.

20 Feb 2013

Air pollution associated with increased deaths after heart attacks

Air pollution contributes to an increased number of deaths among patients who have been admitted to hospital with heart attacks, according to a study published online in the European Heart Journal

20 Feb 2013

Study assesses ischaemic and haemorrhagic risk linked with history of stroke or TIA

Heart and cerebro-vascular disorders represent the two leading causes of death throughout the world. They are sometimes combined in a single patient and their combination represents both a considerable risk to the patient and a therapeutic challenge.

20 Feb 2013

Study determines frequency of genetic variants linked to alcoholism for Spanish population

Research done at the UPV/EHU-University of the Basque Country has determined the frequency of genetic variants linked to alcoholism for the Spanish population, and its incidence not only in individuals with a high level of alcohol intake, but also in individuals with alcohol dependence.

20 Feb 2013

Medical nutrition therapy can play an important role in acne treatment

A study published in the Journal of the Academy of Nutrition and Dietetics has determined that there is increasing evidence of a connection between diet and acne, particularly from high glycemic load diets and dairy products, and that medical nutrition therapy (MNT) can play an important role in acne treatment.

20 Feb 2013

Insight into how NMDA receptors function

In a pair of new papers, researchers at the University of California, San Diego School of Medicine and the Royal Netherlands Academy of Arts and Sciences upend a long-held view about the basic functioning of a key receptor molecule involved in signaling between neurons, and describe how a compound linked to Alzheimer's disease impacts that receptor and weakens synaptic connections between brain cells.

20 Feb 2013

Tiny microscope can help scientists observe neuronal firings in the brain

If you want to read a mouse's mind, it takes some fluorescent protein and a tiny microscope implanted in the rodent's head.

20 Feb 2013

SARS-linked virus well adapted to infect humans, could be treated with drugs to boost immune system, study shows

"A new virus that emerged in the Middle East last year and has killed five people is well adapted to infecting humans but could potentially be treated with drugs that boost the immune system, scientists said on Tuesday," Reuters reports, noting, "The virus, called novel coronavirus or NCoV, is from the same family as the common cold and as SARS, or Severe Acute Respiratory Syndrome."

19 Feb 2013

TP63 gene correlates significantly with worse prognosis of melanoma

Scientists at Queen Mary, University of London have identified a gene present in some melanoma which appears to make the tumour cells more resistant to treatment, according to research published today in the Journal of Experimental Medicine.

19 Feb 2013

Caffeine intake during pregnancy associated with low birth weight babies

Maternal nutrition is important to a developing embryo and to the health of the child later in life. Supplementing the diet with specific vitamins is known to increase health of the foetus for example folic acid (vitamin B9) reduces the risk of spina bifida. However not everything an adult might consume is beneficial to a developing baby.

19 Feb 2013

Women appear to have increased risk of implant failure following total hip replacement

Women appear to have a higher risk of implant failure than men following total hip replacement after considering patient-, surgery-, surgeon-, volume- and implant-specific risk factors, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

19 Feb 2013

Cholesterol metabolism regulated by bacteria in the small intestine

Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, show that cholesterol metabolism is regulated by bacteria in the small intestine. These findings may be important for the development of new drugs for cardiovascular disease.

19 Feb 2013

Temper outbursts linked to depression in OCD children

Temper outbursts are common in children with obsessive-compulsive disorder and are associated with depression symptoms, UK researchers report.

19 Feb 2013

Depression links PTSD to life quality in bipolar disorder

The association between post-traumatic stress disorder and mental health-related quality of life among individuals with bipolar disorder may be mediated by depressive symptoms, the results of a US study indicate.

19 Feb 2013

Article details mechanism by which long non-coding RNA-activators promote gene expression

Long segments of RNA- encoded in our DNA but not translated into protein-are key to physically manipulating DNA in order to activate certain genes, say researchers at The Wistar Institute. These non-coding RNA-activators (ncRNA-a) have a crucial role in turning genes on and off during early embryonic development, researchers say, and have also been connected with diseases, including some cancers, in adults.

18 Feb 2013

Scientists discover new subgroups of GC patients with different disease's characteristics

A collaboration between Portuguese and Italian scientists has discovered new subgroups of stomach cancer patients with different disease's characteristics, an information that is hoped will help improving the clinical management of a disease that still kills a dismaying 3 out of 4 patients.

18 Feb 2013

UC-led study takes a new direction in examining availability of healthy foods for urban populations

University of Cincinnati-led research takes a new direction in examining the availability of healthy foods for urban populations by examining the commuting patterns of its residents.

18 Feb 2013

Study shows how gene mutations affect calcium pathway in arrhythmia

Using powerful X-rays, University of British Columbia researchers have reconstructed a crime scene too small for any microscope to observe - and caught the culprit of arrhythmia in action.

17 Feb 2013

Gut microbes can affect severity of kidney disease brought on by melamine poisoning

Microbes present in the gut can affect the severity of kidney disease brought on by melamine poisoning, according to an international study led by Professor Wei Jia at the University of North Carolina in collaboration with the research group of Professor Jeremy Nicholson at Imperial College London.

16 Feb 2013

Parkinson's-related mutations may also affect vision

The most common genetic cause of Parkinson's is not only responsible for the condition's distinctive movement problems but may also affect vision, according to new research by scientists at the University of York.

16 Feb 2013

X linked News and Research

Antibody-drug conjugates (ADCs): an interview with Dr Marco Timmers, CSO at Synthon Biopharmaceuticals

Air pollution associated with increased deaths after heart attacks

Study assesses ischaemic and haemorrhagic risk linked with history of stroke or TIA

Study determines frequency of genetic variants linked to alcoholism for Spanish population

Medical nutrition therapy can play an important role in acne treatment

Insight into how NMDA receptors function

Tiny microscope can help scientists observe neuronal firings in the brain

SARS-linked virus well adapted to infect humans, could be treated with drugs to boost immune system, study shows

TP63 gene correlates significantly with worse prognosis of melanoma

Caffeine intake during pregnancy associated with low birth weight babies

Women appear to have increased risk of implant failure following total hip replacement

Cholesterol metabolism regulated by bacteria in the small intestine

Temper outbursts linked to depression in OCD children

Depression links PTSD to life quality in bipolar disorder

Article details mechanism by which long non-coding RNA-activators promote gene expression

Scientists discover new subgroups of GC patients with different disease's characteristics

UC-led study takes a new direction in examining availability of healthy foods for urban populations

Study shows how gene mutations affect calcium pathway in arrhythmia

Gut microbes can affect severity of kidney disease brought on by melamine poisoning

Parkinson's-related mutations may also affect vision

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