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Purine metabolism disruptions highlighted as crucial in Parkinson’s disease development

Purine metabolism disruptions highlighted as crucial in Parkinson’s disease development

Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function.

26 Sep 2024

Carotenoid phytoene shows potential in slowing Alzheimer’s plaque formation and increasing lifespan

Carotenoid phytoene shows potential in slowing Alzheimer’s plaque formation and increasing lifespan

Researchers from the Colour and Food Quality group at the Faculty of Pharmacy (University of Seville), in collaboration with Dr. Marina Ezcurra's group at the University of Kent (UK), have shown that the carotenoid phytoene increases the lifespan of the nematode Caenorhabditis elegans and can slow the onset of paralysis associated with the formation of amyloid plaques in a model of Alzheimer's disease.

26 Sep 2024

Innovative CAR-T cells effectively target glioblastoma with reduced toxicity

Innovative CAR-T cells effectively target glioblastoma with reduced toxicity

Glioblastoma is the most common and most aggressive primary brain tumor, with an average survival after diagnosis of less than two years, and against which current treatments remain ineffective.

26 Sep 2024

UMC Utrecht study uncovers 29 novel antibodies against Klebsiella pneumoniae

UMC Utrecht study uncovers 29 novel antibodies against Klebsiella pneumoniae

Research at UMC Utrecht has identified 29 novel antibodies against the bacterium Klebsiella pneumoniae, an important cause of drug-resistant infections.

26 Sep 2024

New discovery could lead to improved treatments for age- and cancer-related muscle degeneration

New discovery could lead to improved treatments for age- and cancer-related muscle degeneration

With the global population aging rapidly, sarcopenia, a condition that affects millions of older adults and severely diminishes their quality of life, is emerging as an urgent public health issue.

26 Sep 2024

Genetic factors that make the bacteria behind cholera so dangerous uncovered

Genetic factors that make the bacteria behind cholera so dangerous uncovered

Study reveals key genetic factors in Vibrio cholerae O1 that drive cholera transmission and severity, highlighting targets for novel therapeutic strategies.

26 Sep 2024

Why children with Down’s syndrome are predisposed to developing leukaemia

Why children with Down’s syndrome are predisposed to developing leukaemia

The study uncovers mechanisms linking Down syndrome to leukemia, emphasizing the role of oxidative stress and genetic alterations in fetal blood development.

26 Sep 2024

Targeting tumor immunity with transferrin receptor-directed photodynamic therapy

Targeting tumor immunity with transferrin receptor-directed photodynamic therapy

This new article publication from Acta Pharmaceutica Sinica B, discusses a transferrin receptor-targeted immunostimulant for photodynamic immunotherapy against metastatic tumors through β-catenin/CREB interruption.

26 Sep 2024

Researchers explore new metabolic pathway to fight cancer

Researchers explore new metabolic pathway to fight cancer

When an aggressive cancer launches an invasion on the human body, anything that can be done to slow down or better understand that fast-paced assault is going to be a bonus.

26 Sep 2024

Study highlights importance of empathetic care for children in pain

Study highlights importance of empathetic care for children in pain

Whether it's a sore arm or a fear of injections, how a child is treated when they present with pain could significantly affect how they respond to and manage pain later in life.

25 Sep 2024

Study uncovers genetic changes linked to leukemia risk in people with Down's syndrome

Study uncovers genetic changes linked to leukemia risk in people with Down's syndrome

People with Down's syndrome face a higher risk of developing Leukemia. Now researchers from the University of Copenhagen and Stanford University explain why, by identifying specific changes in blood cells of people with Down's syndrome.

25 Sep 2024

Centenarians' stem cells unlock secrets to healthy aging

Centenarians' stem cells unlock secrets to healthy aging

Individuals who display exceptional longevity provide evidence that humans can live longer, healthier lives.

25 Sep 2024

New AI technology promises enhanced breast cancer detection

New AI technology promises enhanced breast cancer detection

Women worldwide could see better treatment with new AI technology which enables better detection of damaged cells and more precisely predict the risk of getting breast cancer, shows new research from the University of Copenhagen.

25 Sep 2024

Breakthrough research offers hope for improved treatment of chronic wounds

Breakthrough research offers hope for improved treatment of chronic wounds

Novel research, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, has identified key molecular targets that could significantly enhance the healing of both acute and chronic wounds.

25 Sep 2024

Study sheds light on mechanisms behind liver fibrosis and potential therapies

Study sheds light on mechanisms behind liver fibrosis and potential therapies

New research from the University of Pittsburgh School of Pharmacy sheds light on the processes that lead to liver fibrosis and suggests a novel treatment approach for this common and serious condition.

25 Sep 2024

Pigs identified as possible carriers of rat hepatitis E virus infecting humans

Pigs identified as possible carriers of rat hepatitis E virus infecting humans

New research suggests that pigs may function as a transmission vehicle for a strain of the hepatitis E virus (HEV) common in rats that has recently been found to infect humans.

25 Sep 2024

Study: Obstructive sleep apnea may be a risk factor for abdominal aortic aneurysms

Study: Obstructive sleep apnea may be a risk factor for abdominal aortic aneurysms

Obstructive sleep apnea may be a risk factor for developing abdominal aortic aneurysms, according to researchers from the University of Missouri School of Medicine and NextGen Precision Health.

25 Sep 2024

New AI tool revolutionizes drug discovery for rare diseases

New AI tool revolutionizes drug discovery for rare diseases

There are more than 7,000 rare and undiagnosed diseases globally.

25 Sep 2024

Chemical genetics uncovers promising anti-COVID compounds

Chemical genetics uncovers promising anti-COVID compounds

This new article publication from Acta Pharmaceutica Sinica B, discusses the identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics.

25 Sep 2024

Extracellular vesicles play key role in brain development

Extracellular vesicles play key role in brain development

Extracellular vesicles (EVs) are tiny bubbles released by cells, acting as cargo vessels through which cells exchange signals and thus communicate.

25 Sep 2024

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