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SLU researchers make advances in understanding plaque-causing protein in neurological disorders

In a recent paper published in the Journal of Biological Chemistry Yuna Ayala, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, and her research team made advances in understanding how a protein causes damaging plaques to build up in neurodegenerative illnesses like amyotrophic lateral sclerosis (ALS) and a form of dementia called frontotemporal lobar degeneration.

19 Apr 2017

Study paves way to develop noninvasive diagnostic test for colorectal cancer

The type of bacteria in your gut may help diagnose colorectal cancer. Researchers at Baylor College of Medicine and other institutions have identified specific types of bacteria that seem to be abundant in individuals with colorectal cancer.

19 Apr 2017

Salty food doesn’t make you thirsty; it makes you hungry, say experts

A new study has shown that eating salty food does not make you thirsty, but rather, it diminishes thirst. What eating salty food does do is increase the need for energy and therefore food.

19 Apr 2017

Doctors perform first-ever robotic, minimally-invasive surgical removal of stage IV tumor thrombus

A surgical team at Keck Medicine of the University of Southern California has pushed the boundaries of clinical care by performing the first-ever robotic, minimally-invasive surgical removal of a stage IV tumor thrombus, which is when a kidney cancer tumor extends into the heart.

19 Apr 2017

Babies with low or high birth weight may be at increased risk for developing NAFLD, study suggests

A study published in the Journal of Pediatrics suggests that children born with lower or higher weight than normal may be at increased risk for developing nonalcoholic fatty liver disease.

18 Apr 2017

Research reveals how liver progenitor cells contribute to development of hepatic tumors

The malignant transformation of hepatocytes is the origin of most hepatocellular carcinomas, an aggressive type of liver cancer with high mortality rates. But these cells do not act alone.

18 Apr 2017

TUM study shows link between zinc supply in the body and cardiac function

In addition to essential metabolic functions, the level of zinc in the body also affects the heart muscle. When oxidative stress occurs, it may be due to a shortage of zinc, which can be determined by examining the heart muscle.

18 Apr 2017

Researchers find new way to prevent graft-versus-host disease after stem cell transplants

Through experimental work, an international team of researchers led by City of Hope's Defu Zeng, professor of diabetes immunology and hematopoietic cell transplantation, believe they may have found a way to prevent graft-versus-host disease after stem cell transplants while retaining the transplants' positive effects on fighting leukemia and lymphoma.

18 Apr 2017

Research sheds new light on the body's response to high salt intake

When you eat salty food, you get thirsty and drink water. Right? Maybe in the short-term, but within 24 hours, you actually get less thirsty because your body starts to conserve and produce more water.

17 Apr 2017

Discovery of additional viral reservoir reveals new target for HIV cure research

HIV cure research to date has focused on clearing the virus from T cells, a type of white blood cell that is an essential part of the immune system.

17 Apr 2017

Differences found in cancer occurrence within African and US born blacks

The cancer profile of African-born blacks differs from that of United States-born blacks and varies by region of birth, according to a new study. The study, appearing in CANCER, suggests differences in environmental, cultural, social, and genetic factors, and points to an opportunity to study the risk factors associated with the cancer burden in African-born blacks to help create targeted interventions.

14 Apr 2017

Study finds depression and SUD to be strongest risk factors for prescription opioid overdose

Individuals suffering from a substance use disorder (SUD) or depression are among those at highest risk for a serious prescription opioid overdose, according to a study published in Pain Medicine.

13 Apr 2017

Study may provide insight into how R-LA promotes death of hepatoma cells

A new study that measured metabolite levels over time in starved rat liver cancer cells showed that treatment with a form of alpha-lipoic acid (LA) inhibited glucose uptake and glycolysis, and led to decreased cellular glucose production from non-carbohydrate sources, which may help explain how the naturally occurring R enantiomeric form of LA (R-LA) promotes the death of hepatoma cells.

12 Apr 2017

Researchers design first light-activated drug for treatment of pain

A team of the Institute of Neurosciences of the University of Barcelona has participated in the design of the first light-activated drug -the JF-NP-26, for the treatment of pain, according to a research with animal models published in the journal eLife.

11 Apr 2017

Researchers map gene activity to reveal how the liver performs different functions

If you get up in the morning feeling energetic and clearheaded, you can thank your liver for manufacturing glucose before breakfast time. Among a host of other vital functions, it also clears our body of toxins and produces most of the carrier proteins in our blood.

11 Apr 2017

High level of protein appears to diminish energy burning power of brown fat

Too much of a protein already associated with prostate cancer appears to also diminish the energy burning power of brown fat, scientists report.

10 Apr 2017

MIT engineers develop more sensitive approach to reveal ovarian tumors

Most ovarian cancer is diagnosed at such late stages that patients' survival rates are poor. However, if the cancer is detected earlier, five-year survival rates can be greater than 90 percent.

10 Apr 2017

Fitness and wellness coaching before surgery could reduce patient's hospital stay, study finds

A 5K fun run shouldn't involve more physical preparation than major surgery, but that's the disconnect Michael Englesbe, M.D., sees all too often.

10 Apr 2017

FDA grants approval for two drugs to treat hepatitis C virus in children

The U.S. Food and Drug Administration today approved supplemental applications for Sovaldi (sofosbuvir) and Harvoni (ledipasvir and sofosbuvir) to treat hepatitis C virus (HCV) in children ages 12 to 17. Harvoni and Sovaldi were previously approved to treat HCV in adults.

7 Apr 2017

FDA authorizes marketing of first direct-to-consumer GHR tests for certain diseases

The U.S. Food and Drug Administration today allowed marketing of 23andMe Personal Genome Service Genetic Health Risk (GHR) tests for 10 diseases or conditions.

6 Apr 2017

Liver News and Research

SLU researchers make advances in understanding plaque-causing protein in neurological disorders

Study paves way to develop noninvasive diagnostic test for colorectal cancer

Salty food doesn’t make you thirsty; it makes you hungry, say experts

Doctors perform first-ever robotic, minimally-invasive surgical removal of stage IV tumor thrombus

Babies with low or high birth weight may be at increased risk for developing NAFLD, study suggests

Research reveals how liver progenitor cells contribute to development of hepatic tumors

TUM study shows link between zinc supply in the body and cardiac function

Researchers find new way to prevent graft-versus-host disease after stem cell transplants

Research sheds new light on the body's response to high salt intake

Discovery of additional viral reservoir reveals new target for HIV cure research

Differences found in cancer occurrence within African and US born blacks

Study finds depression and SUD to be strongest risk factors for prescription opioid overdose

Study may provide insight into how R-LA promotes death of hepatoma cells

Researchers design first light-activated drug for treatment of pain

Researchers map gene activity to reveal how the liver performs different functions

High level of protein appears to diminish energy burning power of brown fat

MIT engineers develop more sensitive approach to reveal ovarian tumors

Fitness and wellness coaching before surgery could reduce patient's hospital stay, study finds

FDA grants approval for two drugs to treat hepatitis C virus in children

FDA authorizes marketing of first direct-to-consumer GHR tests for certain diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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