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HIV-positive people with low-level viral load pose ‘almost zero’ risk to sexual partners

People living with HIV who maintain low – but still detectible – levels of the virus and adhere to their antiretroviral regimen have almost zero risk of transmitting it to their sexual partners, according to an analysis published in The Lancet.

23 Jul 2023

Phenotype-based approach to obesity treatment shows promise

In a pilot study of 165 people, Mayo Clinic researchers looked at the effectiveness of two different approaches to weight loss: a standard lifestyle intervention and individualized therapy.

21 Jul 2023

Extracellular vesicles may drive fibrosis in scleroderma

Extracellular vesicles, responsible for cell-to-cell communication, might be a driver of fibrosis in systemic sclerosis, according to a recent paper in Arthritis and Rheumatology.

21 Jul 2023

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Researchers at the Francis Crick Institute and UCL have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS).

21 Jul 2023

Using bacteriophages to treat bladder infections

About one in two women are affected by cystitis during her lifetime, and many suffer from recurrent urinary tract infections.

21 Jul 2023

KIPA shows promise in predicting chemotherapy response in triple negative breast cancer

Researchers at Baylor College of Medicine and collaborating institutions are developing a strategy to predict the response of triple negative breast cancer (TNBC) to chemotherapy, which would be a valuable tool for physicians deciding on the treatment with better probability of success on an individual basis.

21 Jul 2023

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

Trial to investigate the safety and efficacy of ARM210 for the treatment of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT).

21 Jul 2023

Unchained Labs goes all in on Lipid Nanoparticles, acquires Blacktrace Holdings

Unchained Labs, the life sciences company that’s all about getting biologics and gene therapy researchers the right tools for the job, acquired Blacktrace Holdings today.

From Unchained Labs 21 Jul 2023

Advancing vaccine adjuvants: exploring cutting-edge platforms for improved immunization

A group of authors summarized adjuvant mechanisms, characteristics, and applications, seeking to overcome current vaccine limitations.

21 Jul 2023

ECOG-ACRIN launches new trial to evaluate nilotinib and paclitaxel for advanced cancers

The ECOG-ACRIN Cancer Research Group has enrolled the first patient in a new treatment trial to evaluate the effectiveness of adding nilotinib to standard paclitaxel chemotherapy.

20 Jul 2023

Catheter ablation: A new first-line treatment option for atrial fibrillation

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Atrial fibrillation is the most common arrhythmia worldwide, affecting millions of the general population.

20 Jul 2023

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world. But many people would be surprised to learn that this painting offers the first evidence of a disease called familial hypercholesterolemia (FH).

20 Jul 2023

Six new Damon Runyon Clinical Investigators announced for 2023

The Damon Runyon Cancer Research Foundation has named six new Damon Runyon Clinical Investigators.

20 Jul 2023

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

Researchers investigated early biomarkers of post-acute sequelae of SARS-CoV-2 infection in individuals intensively sampled during the acute phase of COVID-19.

20 Jul 2023

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Researchers reported on Nurr1 as a promising therapeutic target for managing Parkinson's disease (PD).

20 Jul 2023

Donanemab: A trailblazer for Alzheimer's disease treatment?

A recent study evaluated the efficacy and side effects of donanemab, an antibody that could possibly clear brain amyloid plaque in early symptomatic Alzheimer disease (AD).

20 Jul 2023

How the COVID-19 pandemic altered antibiotic prescribing for common bacterial infections

Investigators evaluated the impact of the coronavirus disease 2019 pandemic on the use of antibiotics in primary care for common infections.

20 Jul 2023

T cells can be used to identify type 1 diabetes risk, study shows

Scripps Research scientists have shown that analyzing a certain type of immune cell in the blood can help identify people at risk of developing type 1 diabetes, a life-threatening autoimmune disease.

19 Jul 2023

Study provides new insights into how SARS-CoV-2 affects glucose metabolism

Research conducted at the University of São Paulo (USP) in Brazil shows that SARS-CoV-2, the virus that causes COVID-19, can infect liver cells (hepatocytes), stimulating glucose production and leading to a condition similar to diabetes (hyperglycemia) in hospitalized patients, even if their blood sugar level was normal before they were admitted to hospital.

19 Jul 2023

New method could make post-stroke motor rehabilitation more effective and affordable

The longest nerve in the human body starts in the brain and meanders its way down the neck and into the chest, where it splits into separate branches, winding its twisting tendrils to touch each internal organ.

19 Jul 2023

Therapy News and Research

HIV-positive people with low-level viral load pose ‘almost zero’ risk to sexual partners

Phenotype-based approach to obesity treatment shows promise

Extracellular vesicles may drive fibrosis in scleroderma

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Using bacteriophages to treat bladder infections

KIPA shows promise in predicting chemotherapy response in triple negative breast cancer

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

Unchained Labs goes all in on Lipid Nanoparticles, acquires Blacktrace Holdings

Advancing vaccine adjuvants: exploring cutting-edge platforms for improved immunization

ECOG-ACRIN launches new trial to evaluate nilotinib and paclitaxel for advanced cancers

Catheter ablation: A new first-line treatment option for atrial fibrillation

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

Six new Damon Runyon Clinical Investigators announced for 2023

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Donanemab: A trailblazer for Alzheimer's disease treatment?

How the COVID-19 pandemic altered antibiotic prescribing for common bacterial infections

T cells can be used to identify type 1 diabetes risk, study shows

Study provides new insights into how SARS-CoV-2 affects glucose metabolism

New method could make post-stroke motor rehabilitation more effective and affordable

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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