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Metabolic syndrome is the new 'silent killer', warn researchers

For decades, American waistlines have been expanding and there is increasing cause for alarm. Researchers from the Charles E. Schmidt College of Medicine at Florida Atlantic University make the case that metabolic syndrome -- a cluster of three of more risk factors that include abdominal obesity, high triglycerides, high blood pressure, abnormal lipids, and insulin resistance, a precursor of type 2 diabetes -- is the new "silent killer," analogous to hypertension in the 1970s.

6 Apr 2017

Researchers use modified AAV as ‘Trojan Horse’ for delivering genes to restore congenital deafness

There are more than 300 genetic defects that have been found to prevent the hair cells in the human inner ear, the sensory cells of the ear as it were, from working properly.

6 Apr 2017

Researchers achieve new step towards treatment of myotubular myopathy using gene therapy

A team of researchers in France, led by Dr. Ana Buj-Bello (Genethon/Inserm) and teams at the University of Washington and Harvard Medical School in the United States, achieved a new step towards the treatment of myotubular myopathy by gene therapy.

5 Apr 2017

IBD patients with longer duration of disease have higher risk of developing NAFLD

Research led by a Houston Methodist gastroenterologist shows that patients who have inflammatory bowel disease (IBD) for more than two decades have a higher risk of developing nonalcoholic fatty liver disease (NAFLD).

5 Apr 2017

Number of HIV-positive cancer patients in the U.S. projected to decrease through 2030

As the population of people living with HIV in the United States ages, the burden of cancer for these patients is expected to shift away from cancers linked to AIDS and toward malignancies that affect the general population, according to a new study led by a University of North Carolina at Chapel Hill researcher.

5 Apr 2017

Magnetic resonance technology can improve fatty liver diagnosis

Taking tissue samples from the liver to diagnose fatty liver can be replaced in most cases by a painless magnetic resonance investigation.

5 Apr 2017

Oral gut microbe treatment improves fatty liver in mice

Oral administration of a commensal gut microbe, Faecalibacterium prausnitzii, improves fatty liver in mice. F. prausnitzii is considered one of the most important bacterial indicators of a healthy gut.

5 Apr 2017

Liver shows positive response to leptin therapy in patients with partial lipodystrophy, study finds

Researchers at Michigan Medicine have found the livers of patients with a rare disease that affects metabolism have responded positively to leptin therapy.

5 Apr 2017

Stanford-led researchers use microbubbles and ultrasound to detect malignant cancers

A team led by researchers from the Stanford University School of Medicine has demonstrated a way to diagnose cancer without resorting to surgery, raising the possibility of far fewer biopsies.

5 Apr 2017

Low and high birth weights linked to severity of liver disease in children

Researchers at University of California San Diego School of Medicine, with a cohort of clinical collaborators from across the United States, have demonstrated the impact of low and high birth weights in developing Non Alcoholic Fatty Liver Disease (NAFLD), a chronic disease that often leads to a need for organ transplantation.

4 Apr 2017

Treating PCOS in adolescent girls may help prevent future subfertility, research suggests

In adolescent girls with polycystic ovary syndrome (PCOS), bringing the amount of abdominal visceral fat and liver fat down to normal restores ovulation, normalizes the symptoms of androgen excess, and may help prevent future subfertility, new research from Spain suggests.

4 Apr 2017

Australia has potential to eradicate hepatitis C in 10–15 years, says expert

Australia has the potential to eradicate hepatitis C in the next 10–15 years, according to Associate Professor Simone Strasser, gastroenterologist at Royal Prince Alfred Hospital in Sydney.

4 Apr 2017

Global symposium focuses on chemistry and biological effects of maple food product

The first-ever global symposium, solely dedicated to sharing the latest scientific discoveries on the potential health benefits of 100% pure maple products from Canada, took place on April 2 in San Francisco at the 253rd annual meeting of the American Chemical Society (ACS), the largest scientific society in the world.

4 Apr 2017

Extreme short and long telomeres linked to increased cancer risk

The length of the telomere "caps" of DNA that protect the tips of chromosomes may predict cancer risk and be a potential target for future therapeutics, University of Pittsburgh Cancer Institute scientists will report today at the AACR Annual Meeting in Washington, D.C.

3 Apr 2017

Mother's alcohol misuse before conception may have lifelong negative effects on offspring

Mothers who binge drink before they become pregnant may be more likely to have children with high blood sugar and other changes in glucose function that increase their risk of developing diabetes as adults, according to a new study conducted in rats.

3 Apr 2017

Study shows how early-life BPA exposure leads to NAFLD in adulthood

Exposure during infancy to the common plasticizer bisphenol A "hijacks" and reprograms genes in the liver of newborn rats, leading to nonalcoholic fatty liver disease in adulthood.

2 Apr 2017

New report highlights need for rapid research progress and improved outcomes in pancreatic cancer

The new report highlighting trends in cancer released today by the American Cancer Society, the Centers for Disease Control and Prevention (CDC) and the National Cancer Institute (NCI) points to the urgent need for more research and funding in pancreatic cancer.

31 Mar 2017

Single dose of siRNA molecule offers protection against heart attack and stroke in high-risk patients

Even a single dose of a specific ribonucleic acid molecule, known as a small interfering RNA (siRNA), offers patients at high risk of cardiovascular disease long-lasting protection against high LDL cholesterol - one of the main risk factors for heart attack and stroke.

30 Mar 2017

Rare ‘beneficial’ genetic mutations may provide clues to preventing heart attacks

Natural genetic changes can put some people at high risk of certain conditions, such as breast cancer, Alzheimer's disease or high blood pressure. But in rare cases, genetic errors also can have the opposite effect, protecting individuals with these helpful genetic mistakes from developing common diseases.

30 Mar 2017

Cold-induced fat-like molecules help fuel metabolism in mice

Activated by cold, the small amounts of brown fat scattered around your body can burn calories to warm you up. They also can help to lower insulin resistance and other conditions implicated in type 2 diabetes and obesity.

29 Mar 2017

Liver News and Research

Metabolic syndrome is the new 'silent killer', warn researchers

Researchers use modified AAV as ‘Trojan Horse’ for delivering genes to restore congenital deafness

Researchers achieve new step towards treatment of myotubular myopathy using gene therapy

IBD patients with longer duration of disease have higher risk of developing NAFLD

Number of HIV-positive cancer patients in the U.S. projected to decrease through 2030

Magnetic resonance technology can improve fatty liver diagnosis

Oral gut microbe treatment improves fatty liver in mice

Liver shows positive response to leptin therapy in patients with partial lipodystrophy, study finds

Stanford-led researchers use microbubbles and ultrasound to detect malignant cancers

Low and high birth weights linked to severity of liver disease in children

Treating PCOS in adolescent girls may help prevent future subfertility, research suggests

Australia has potential to eradicate hepatitis C in 10–15 years, says expert

Global symposium focuses on chemistry and biological effects of maple food product

Extreme short and long telomeres linked to increased cancer risk

Mother's alcohol misuse before conception may have lifelong negative effects on offspring

Study shows how early-life BPA exposure leads to NAFLD in adulthood

New report highlights need for rapid research progress and improved outcomes in pancreatic cancer

Single dose of siRNA molecule offers protection against heart attack and stroke in high-risk patients

Rare ‘beneficial’ genetic mutations may provide clues to preventing heart attacks

Cold-induced fat-like molecules help fuel metabolism in mice

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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