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New Internet tool may help analyze genes based on their evolutionary profile

Two major revolutions, one genomic and one in informatics, are completely changing the face of biomedical research. Every day all over the world, millions of genetic sequences -- from disease-related genes to complete genomes of plants, animals, bacteria and viruses -- are resolved, identified and dissected.

26 Jun 2015

Biontech, Siemens enter into strategic collaboration on manufacture of personalized cancer vaccines

Siemens and BioNTech AG, a fully integrated biotechnology company developing truly personalized cancer immunotherapies, have entered into a strategic collaboration.

25 Jun 2015

Detroit-area patients contribute to national study that redefines diagnosis, treatment of glioma

Sixty-seven patients from the Hermelin Brain Tumor Center at Henry Ford Hospital and their families made important contributions to a national cancer study that proposes a change in how some brain tumors are classified - and ultimately treated.

25 Jun 2015

Myriad Genetics, Chris4Life launch educational campaign to teach individuals about risk of hereditary cancer

Chris4Life Colon Cancer Foundation, a Washington, D.C.-based national non-profit organization, and Myriad Genetics, a leader in personalized medicine, today announced their “What’s Your History” family history week (June 24-30, 2015).

25 Jun 2015

Study shows cystic fibrosis is more deadly for Hispanic than non-Hispanic patients

Cystic fibrosis is more deadly for Hispanic than non-Hispanic patients, a disparity that is not explained by differences in their access to health care, according to a new study from the Stanford University School of Medicine.

25 Jun 2015

Larrea Biosciences merged into Gordian Holdings

Larrea Biosciences has been merged into Gordian Holdings, Inc. "Marshalling the Body's best Offense and Defense against Disease, Its own Immune System, through Immunotherapy." Gordian Holdings obtained the rights from OnkologixRx, Inc., for the Markets in China and North America.

25 Jun 2015

Scientific collaboration pinpoints genetic cause of rare form of blindness in newborn babies

A scientific collaboration, involving the Manchester Centre for Genomic Medicine at Saint Mary's Hospital, UK, and the Telethon Institute of Genetics and Medicine in Naples, Italy, has pinpointed the genetic cause of a rare form of blindness, which can present itself as a key-hole shaped defect in the eye in newborn babies.

24 Jun 2015

Purdue University researchers pinpoint gene that controls permeability, calcium content of soybean seed

Purdue University researchers have pinpointed the gene that controls whether soybean seed coats are hard or permeable, a finding that could be used to develop better varieties for southern and tropical regions, enrich the crop's genetic diversity and boost the nutritional value of soybeans.

23 Jun 2015

Experimental vaccine candidate can stimulate immune system activity to prevent HIV infection

New research led by scientists at The Scripps Research Institute (TSRI), International AIDS Vaccine Initiative (IAVI) and The Rockefeller University shows in mice that an experimental vaccine candidate designed at TSRI can stimulate the immune system activity necessary to stop HIV infection. The findings could provide key information for the development of an effective AIDS vaccine.

22 Jun 2015

Study opens new area of discovery for different aspects of cell biology, biomedical research

Every cell in the body uses phosphorylation, the process of adding a chemical tag to control a protein's function and fate, such as when it moves from one part of a cell to another or binds to other proteins.

19 Jun 2015

UNC Lineberger scientists contribute to better understanding of genetic mutations in melanoma

UNC Lineberger Comprehensive Cancer Center researchers have significantly contributed to a better understanding of the genetic alterations found in cutaneous melanoma, the most lethal form of skin cancer, as part of a multi-institution, international effort of The Cancer Genome Atlas.

19 Jun 2015

Scientists identify four melanoma subtypes that share common 'downstream' signaling pathways

Cutaneous melanoma, the most deadly form of skin cancer, is now believed to be divided into four distinct genomic subtypes, say researchers at The University of Texas MD Anderson Cancer Center, a finding that could prove valuable in the ever-increasing pursuit of personalized medicine.

19 Jun 2015

Mayo Clinic, TGen researchers help launch national clinical trial to treat advanced skin cancer patients

Mayo Clinic and the Translational Genomics Research Institute are helping launch a national clinical trial that will apply the latest in precision medicine to treat advanced melanoma skin cancer.

19 Jun 2015

Sequence of immunizations could be the promising route to HIV vaccine

The secret to preventing HIV infection lies within the human immune system, but the more-than-25-year search has so far failed to yield a vaccine capable of training the body to neutralize the ever-changing virus. New research from The Rockefeller University, and collaborating institutions, suggests no single shot will ever do the trick. Instead, the scientists find, a sequence of immunizations might be the most promising route to an HIV vaccine.

19 Jun 2015

International researchers identify previously unknown genetic immunodeficiency

An analysis of five families has revealed a previously unknown genetic immunodeficiency, says an international team led by researchers from Boston Children's Hospital. The condition, linked to mutations in a gene called DOCK2, deactivates many features of the immune system and leaves affected children open to a unique pattern of aggressive, potentially fatal infections early in life.

19 Jun 2015

Nucleoporin proteins play significant role in maintaining embryonic stem cells

What if you found out that pieces of your front door were occasionally flying off the door frame to carry out chores around the house? That's the kind of surprise scientists at the Salk Institute experienced with their recent discovery that nucleoporins -- proteins that act as cellular 'doorways' to help manage what goes in and out of a cell's nucleus -- are actually much bigger players in expressing genes than previously thought.

19 Jun 2015

Study demonstrates potential of new approach for sorting out BRCA1 gene variants

Patients seeking certainty in genetic tests often receive a perplexing result. Many learn they carry a 'variant of unknown significance' of a disease-linked gene. Such variants might -- or equally might not -- increase disease risk.

19 Jun 2015

$Phase 3 study shows Vectibix meets primary endpoint in patients with chemorefractory wild-type KRAS mCRC$

Phase 3 study shows Vectibix meets primary endpoint in patients with chemorefractory wild-type KRAS mCRC

Amgen today announced that a Phase 3 study evaluating Vectibix (panitumumab) and best supportive care (BSC) met its primary endpoint, demonstrating a statistically significant improvement in overall survival (OS) in patients with chemorefractory wild-type KRAS (exon 2) metastatic colorectal cancer (mCRC) compared to those patients treated with BSC alone.

19 Jun 2015

Researchers track down key gene mutation responsible for causing acute lymphoblastic leukemia

Two medical researchers from the Children's Hospital of Michigan and the Wayne State University School of Medicine have published the results of a nearly 10-year investigation that identified a key gene mutation that can trigger acute lymphoblastic leukemia, or ALL, and several other types of cancer.

18 Jun 2015

Researchers highlight important factors that impact early-stage breast cancer patients' access to BCT

The first comprehensive national review of breast-conserving therapy (BCT) shows that over the last 13 years rates of this treatment modality for early-stage breast cancer have increased at a steady pace. However, the review also highlights important demographic factors that impact which patients have access to BCT.

18 Jun 2015

Mutation News and Research

New Internet tool may help analyze genes based on their evolutionary profile

Biontech, Siemens enter into strategic collaboration on manufacture of personalized cancer vaccines

Detroit-area patients contribute to national study that redefines diagnosis, treatment of glioma

Myriad Genetics, Chris4Life launch educational campaign to teach individuals about risk of hereditary cancer

Study shows cystic fibrosis is more deadly for Hispanic than non-Hispanic patients

Larrea Biosciences merged into Gordian Holdings

Scientific collaboration pinpoints genetic cause of rare form of blindness in newborn babies

Purdue University researchers pinpoint gene that controls permeability, calcium content of soybean seed

Experimental vaccine candidate can stimulate immune system activity to prevent HIV infection

Study opens new area of discovery for different aspects of cell biology, biomedical research

UNC Lineberger scientists contribute to better understanding of genetic mutations in melanoma

Scientists identify four melanoma subtypes that share common 'downstream' signaling pathways

Mayo Clinic, TGen researchers help launch national clinical trial to treat advanced skin cancer patients

Sequence of immunizations could be the promising route to HIV vaccine

International researchers identify previously unknown genetic immunodeficiency

Nucleoporin proteins play significant role in maintaining embryonic stem cells

Study demonstrates potential of new approach for sorting out BRCA1 gene variants

Phase 3 study shows Vectibix meets primary endpoint in patients with chemorefractory wild-type KRAS mCRC

Researchers track down key gene mutation responsible for causing acute lymphoblastic leukemia

Researchers highlight important factors that impact early-stage breast cancer patients' access to BCT

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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