Protein C News and Research

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University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Emad Ibrahim, M.D., director of the Male Fertility Research Program at The Miami Project to Cure Paralysis and the clinical andrology lab at the Desai Sethi Urology Institute at the University of Miami Miller School of Medicine, has been awarded a $3.25 million grant by the Department of Defense for a four-year study on the use of an oral medication to treat an infertility issue that affects most men with spinal cord injury.

27 Feb 2023

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Nearly 100% of cases of amyotrophic lateral sclerosis - the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig's disease - involve the buildup of a protein called TDP-43.

27 Feb 2023

Different cellular building blocks are not produced at the same time, research shows

Textbooks will tell you that in dividing cells, the production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level.

27 Feb 2023

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

The number of specialized immune cells available for fighting skin cancer doubled when a new treatment blocked their escape from melanoma tumors, experiments in mice and human cells show.

27 Feb 2023

Nutritional analysis: Gluten-free products are not on par with gluten-containing counterparts

A research team at the University of the Basque Country has spent 9 years monitoring gluten-free products to analyze whether they are nutritionally deficient.

27 Feb 2023

What is the effect of maternal circulating amino acids on offspring birthweight?

Researchers examined the effect of serum levels of 20 amino acids in a mother during pregnancy on offspring birthweight in a two-sample summary data Mendelian randomization framework.

27 Feb 2023

Rapid AAV Titer for Bioprocessing in Gene Therapy

In this article, News-Medical talks to Sartorius about biosensing and bioprocessing in gene therapy, while also discussing the various products Sartorius produces in order to aid in this.

From Sartorius 27 Feb 2023

Viable treatment option for patients with advanced cervical cancer

A recent University of Kentucky Markey Cancer Center study suggests a new radiopharmaceutical compound may be a viable treatment option for patients with advanced cervical cancer.

25 Feb 2023

Significance of mathematical modeling in understanding complex biological processes

Humans and animals detect different stimuli such as light, sound, and odor through nerve cells, which then transmit the information to the brain. Nerve cells must be able to adjust to the wide range of stimuli they receive, which can range from very weak to very strong. To do this, they may become more or less sensitive to stimuli (sensitization and habituation), or they may become more sensitive to weaker stimuli and less sensitive to stronger stimuli for better overall responsiveness (gain control). However, the exact way this happens is not yet understood.

25 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

After more than two years since its discovery, six million deaths, and half a billion reported cases, there is still no effective cure for COVID-19. Even though vaccines have lowered the impact of outbreaks, patients that contract the disease can only receive supportive care while they wait for their own body to clear the infection.

24 Feb 2023

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

24 Feb 2023

University of Vermont Cancer Center to offer a novel, highly effective form of cancer treatment

The University of Vermont Cancer Center will offer a novel, highly effective form of cancer treatment called CAR T-cell therapy beginning in February, when final accreditation and approval to begin treating patients is expected.

24 Feb 2023

UVA research provides new insight into common causes of vision loss

UVA Health scientists have discovered an unknown contributor to harmful blood vessel growth in the eye that could lead to new treatments for blinding macular degeneration and other common causes of vision loss.

24 Feb 2023

Research identifies proteins that may contribute to onset of common metabolic diseases

New research has identified hundreds of proteins that might contribute to the onset of common, chronic metabolic diseases such as type 2 diabetes, and consequently pathways to potential treatments.

24 Feb 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

What nutritional role does carrot powder play in probiotic cheese?

In a recent study published in the Journal of Dairy Science, researchers evaluated carrot powder and its application in probiotic soft cheese.

24 Feb 2023

What is the impact of mushroom consumption on cardiometabolic health?

Researchers reviewed the effect of mushroom consumption on the risk factors, morbidity, and mortality associated with cardiometabolic diseases.

24 Feb 2023

Study suggests fermentation as a sustainable and easily applicable biotechnology to overcome the legume flour technological and sensory drawbacks

Researchers used Mediterranean black chickpea flour in the form of a semi-liquid dough fermented with the bacteria Lactiplantibacillus plantarum to develop fortified semolina pasta with improved nutritional quality.

24 Feb 2023

New discovery could shift the focus of Parkinson’s disease treatment

Researchers from the University of Queensland have identified that a gene associated with an increased risk of Parkinson's Disease also contributes to a build-up of cell debris in the brain.

24 Feb 2023

Protein C News and Research

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Different cellular building blocks are not produced at the same time, research shows

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

Nutritional analysis: Gluten-free products are not on par with gluten-containing counterparts

What is the effect of maternal circulating amino acids on offspring birthweight?

Rapid AAV Titer for Bioprocessing in Gene Therapy

Viable treatment option for patients with advanced cervical cancer

Significance of mathematical modeling in understanding complex biological processes

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

University of Vermont Cancer Center to offer a novel, highly effective form of cancer treatment

UVA research provides new insight into common causes of vision loss

Research identifies proteins that may contribute to onset of common metabolic diseases

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

What nutritional role does carrot powder play in probiotic cheese?

What is the impact of mushroom consumption on cardiometabolic health?

Study suggests fermentation as a sustainable and easily applicable biotechnology to overcome the legume flour technological and sensory drawbacks

New discovery could shift the focus of Parkinson’s disease treatment

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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