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Elevated ST2 biomarker levels strongly indicate heart failure and mortality in HIV patients

Critical Diagnostics, makers of the Presage ST2 Assay, announced today that during a presentation at the American Heart Association Scientific Sessions in Los Angeles, the results of a study demonstrated that elevated levels of the biomarker ST2 in HIV patients was strongly indicative of the development of heart failure and mortality.

9 Nov 2012

Regenstrief Institute and Merck sign five-year collaboration agreement

The Regenstrief Institute and Merck, known as MSD outside the United States and Canada, have signed a five-year agreement to collaborate on a range of projects that will use clinical data to inform personalized delivery of health care.

9 Nov 2012

Study highlights how parents can help children achieve healthy lifestyle habits

According to the Centers for Disease Control and Prevention, about 28% of adolescents are overweight. This means that about 1 in every 5 parents is thinking about how to discuss this with their child. Creating a healthful home environment, modeling healthful behaviors, and providing encouragement and support to adolescents for positive behavior changes may be more effective than communicating with adolescents about weight-related topics, according to a new study released in the November/December 2012 issue of the Journal of Nutrition Education and Behavior.

9 Nov 2012

Regular, moderate coffee consumption may reduce risk of type 2 diabetes

Recent scientific evidence has consistently linked regular, moderate coffee consumption with a reduced risk of developing type 2 diabetes. An update of this research will be presented by experts working in this field at the World Congress on Prevention of Diabetes and Its Complications (WCPD), taking place on 11-14 November in Madrid, Spain.

9 Nov 2012

Positive results from Palatin’s bremelanotide Phase 2B trial on female sexual dysfunction

Palatin Technologies, Inc. today reported positive top-line results, including the successful achievement of statistical significance for the primary endpoint and key secondary endpoints in its Phase 2B clinical trial evaluating the efficacy and safety of bremelanotide for the treatment of female sexual dysfunction (FSD).

9 Nov 2012

New England Journal of Medicine publishes BMC's capnography training video

Physicians at Boston Medical Center (BMC) have developed a training video for health care providers about how to effectively use capnography to monitor ventilation and carbon dioxide levels for patients under anesthesia or conscious sedation. This is the sixth video published in the New England Journal of Medicine's Videos in Clinical Medicine section produced by BMC. It highlights the importance of using capnography to increase patient safety.

9 Nov 2012

FDA accepts Merck’s suvorexant NDA for standard review

Merck, known as MSD outside the United States and Canada, today announced that the New Drug Application (NDA) for suvorexant, the company's investigational insomnia medicine, has been accepted for standard review by the U.S. Food and Drug Administration (FDA).

9 Nov 2012

Viewpoints: Bowles urges 'deficit deal now;' A doctor's take on health law; Preparing N.Y. hospitals for future storms

Going over the fiscal cliff would mean allowing a massive and immediate cut to nearly every major government agency and activity, including those vital to our national security or economic growth.

9 Nov 2012

UIC researchers develop transgenic Alzheimer's mouse with apoE4 gene

Researchers at the University of Illinois at Chicago College of Medicine have developed a transgenic mouse that carries a human gene known to increase risk of Alzheimer's 15-fold. This new mouse mimics the genetics of the human disease more closely than any of the dozen existing mouse models and may prove more useful in the development of candidate drugs to prevent or treat the disease.

9 Nov 2012

Plexxikon updates Zelboraf Phase 1 data on BRAF V600E mutation-positive melanoma

Plexxikon today announced that updated Phase 1 clinical data of Zelboraf (vemurafenib) were presented at the Society for Melanoma Research (SMR) 2012 Congress, held November 8-11 in Los Angeles, CA.

8 Nov 2012

Low antioxidant levels contribute to increased blood pressure during exercise for people with PAD

Low antioxidant levels contribute to increased blood pressure during exercise for people with peripheral arterial disease, according to researchers at Penn State Hershey Heart and Vascular Institute.

8 Nov 2012

Sulfonylureas risk vs metformin points to clear first-line diabetes choice

Using sulfonylureas as a first-line treatment for diabetes is associated with an increased risk for cardiovascular disease events or death compared with the use of metformin, research shows.

8 Nov 2012

Many patients over-optimistic about palliative chemotherapy

A majority of advanced colorectal and lung cancer patients in the USA may not understand that chemotherapy is unlikely to cure them, according to the results of a study published in The New England Journal of Medicine.

8 Nov 2012

Antibiotic choices critical for elderly with bloodstream infections

Failure to treat patients with bacteremia with an appropriate antibiotic is particularly harmful in elderly patients, report researchers.

8 Nov 2012

Key areas of disease neglected by UK funding for infectious diseases

UK funding for infectious diseases research is neglecting some of the diseases that result in the highest rates of death and disability, according to an Article published Online First in The Lancet Infectious Diseases.

8 Nov 2012

FREEDOM results announced

Results from the FREEDOM trial show that coronary artery bypass graft surgery significantly reduces the risk for adverse outcomes compared with percutaneous coronary intervention in patients with diabetes and coronary artery disease.

8 Nov 2012

Canine lymphoma treatment adds up to cystitis

High cumulative doses of the alkylator cyclophosphamide could be to blame for the development of sterile hemorrhagic cystitis in dogs being treated for lymphoma, indicate the results of a US study.

8 Nov 2012

Band counts in infection diagnosis

Even when patients have normal white blood cell counts, elevated band counts may diagnose infection and prompt earlier initiation of antibiotics, report researchers.

8 Nov 2012

Patient recruitment complete for immatics IMA901 Phase 3 trial for renal cell carcinoma

immatics biotechnologies GmbH, a biopharmaceutical company developing rationally designed therapeutic vaccines that are active against cancer, announced today that it has completed patient recruitment into the pivotal phase 3 trial evaluating its lead cancer vaccine IMA901 for renal cell carcinoma (RCC). The trial has completed patient inclusion and it is expected that around 345 patients will be randomized across 10 countries in the US and Europe.

8 Nov 2012

Cardiac arrhythmias: an interview with Dr Andrew Grace

Cardiac arrhythmias are disturbances of the heartbeat. The heart can either go too slowly, which might make people collapse or exhausted; or too quickly.

8 Nov 2012