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Salk professor receives $1.8 million from NOMIS Foundation for research on mechanisms to promote health

Associate Professor Janelle Ayres has been awarded $1.8 million over two years by the NOMIS Foundation to study health as an active process in which microbes--including the trillions of microorganisms that call the human body home--initiate interactions that promote the health of the host.

13 Dec 2018

Study: Loss of tight junction barrier protein results in gastric cancer development

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, claudin 18, occurs in the majority of gastric cancer patients and is correlated with poor prognosis in patients with advanced gastric cancer.

13 Dec 2018

Antibiotic-resistant bacteria could soon be targeted with Alzheimer's drug

Dangerous antibiotic-resistant bacteria could soon be targeted with a drug initially developed to treat Alzheimer's disease.

12 Dec 2018

Microbiological analysis of bacteria that cause food poisoning could save lives

Researchers have made an important discovery that could help save patients with bacterial infections, particularly those suffering from food poisoning.

12 Dec 2018

DNA analysis finds that stethoscopes used in the ICU are teeming with bacteria

Researchers have found that stethoscopes carried by healthcare practitioners in an intensive care (ICU) setting are loaded with a wide range of bacteria.

12 Dec 2018

Genetics study offers hope for new acne treatment

A discovery by researchers from the School of Basic & Medical Biosciences and NIHR Guy's and St Thomas' Biomedical Research Centre could lead to new treatments for severe acne. Scientists found 15 genome regions linked to developing the condition.

12 Dec 2018

Researchers develop new method to produce natural sweetener

A research group from Oulu University has developed a method capable of producing the natural sweetener brazzein. Production of brazzein as a good tasting sweetener has long been in development but until now, no solution for commercial production has been found.

12 Dec 2018

Insights into magnetotactic bacteria could guide development of biological nanorobots

Magnetotactic bacteria are a unique aquatic species which use magnetic nanoparticles as an internal compass to navigate

12 Dec 2018

New collaborative partnership in quest of novel antibiotics

The Global Antibiotic Research and Development Partnership, Eisai Co., Ltd. and Takeda Pharmaceutical Company Limited have signed an agreement for GARDP to access and screen components of Eisai and Takeda's chemical libraries.

12 Dec 2018

SLU researchers explore how fetal exposure to inflammation can alter immunity in newborns

Saint Louis University researchers are studying how fetal exposure to inflammation can alter immune responses after birth.

12 Dec 2018

Brazilian professors propose guidelines for therapeutic use of melatonin

Sixty years after melatonin was isolated and with more than 23,000 published studies showing the many functions of this hormone secreted by the pineal gland, guidelines should be discussed and established for its therapeutic use.

11 Dec 2018

Gut bacteria may modify effectiveness of anti-diabetes drugs

Why do orally-administered drugs for diabetes work for some people but not others? According to researchers at Wake Forest School of Medicine, bacteria that make up the gut microbiome may be the culprit.

11 Dec 2018

People who eat red meat have high levels of chemical associated with heart disease, study finds

Researchers have identified another reason to limit red meat consumption: high levels of a gut-generated chemical called trimethylamine N-oxide, that also is linked to heart disease.

11 Dec 2018

Sacrificial immune cells alert body to infection

Scientists have discovered a new mechanism by which immune cells burst to alert the body to infection with Yersinia pestis.

11 Dec 2018

Scientists discover cellular mechanism that triggers pneumonia in humans

The situation is relatively common, especially in winter. You come down with the flu, which lasts longer than usual. A few days later, you discover you have pneumonia.

10 Dec 2018

Researchers report novel findings on plant hormone

Jasmonic acid is not just the aromatic odor of the plant Jasminum grandiflorum used in cosmetics and perfume industries. Plants wounded by e.g. chewing herbivores produce jasmonic acid as a defense signal, as a phytohormone to mount their defense responses - this includes for example the formation of toxic substances.

10 Dec 2018

Lund University researchers succeed in obtaining dendritic cells by direct reprogramming

For the first time, a research team at Lund University in Sweden has successfully reprogrammed mouse and human skin cells into immune cells called dendritic cells.

9 Dec 2018

MIT researchers develop antimicrobial peptides from South American wasp’s venom

The venom of insects such as wasps and bees is full of compounds that can kill bacteria. Unfortunately, many of these compounds are also toxic for humans, making it impossible to use them as antibiotic drugs.

7 Dec 2018

Scientists unravel how bacterial persister cells manipulate our immune cells

New research, from scientists at Imperial College London, unravels how so-called bacterial persister cells manipulate our immune cells, potentially opening new avenues to finding ways of clearing these bacterial cells from the body, and stopping recurrence of the bacterial infection.

7 Dec 2018