Protein C News and Research

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A network of interacting proteins created to aid drug discovery

Scientists at Open Targets, EMBL's European Bioinformatics Institute, and GSK are revealing the shared basis of diseases using a map of interacting human proteins.

24 Feb 2023

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Researchers characterize the effects of neuronal apolipoprotein E4 on Alzheimer’s disease-associated pathology.

23 Feb 2023

NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

Study finds protein biomarkers in women with perinatal mood and anxiety disorder symptoms

Cedars-Sinai investigators found that women who developed mood and anxiety disorders associated with pregnancy and childbirth had specific altered proteins circulating in their bloodstream in the third trimester.

23 Feb 2023

UMSOM researchers unravel the molecular components involved in abdominal aneurysms

When the artery that supplies the stomach and the liver forms a bulge that ruptures, this medical emergency results in the deaths of 50 percent of patients before they reach the hospital.

23 Feb 2023

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone.

23 Feb 2023

Pathogenicity of SARS-CoV-2 viral components on human periodontal tissues and cells

Researchers assessed the impact of COVID-19 on fibrotic pathogenesis via the deregulation of mitochondrial beta-oxidation.

23 Feb 2023

Study shows antibody-dependent SARS-CoV-2 transmission and pathogenesis

Researchers reported that some monoclonal nAbs directed against distinct RBD epitopes nested inside the SARS-CoV-2 S could substitute ACE2 as a receptor and support fusion between viral and host cell membranes facilitating viral infectivity.

23 Feb 2023

Male non-drinkers who eat more vegetables and less animal fat have a lower risk of diabetes

Researchers examine the associations between nutrient intake, alcohol use, and diabetes incidence in Japanese residents.

22 Feb 2023

UCI-led study uncovers how APOBEC3B protein could protect cells against RNA viruses

A new University of California, Irvine-led study uncovers how a protein, APOBEC3B, could protect cells against many different types of RNA viruses like respiratory syncytial virus (RSV), SARS-CoV2, influenza virus, poliovirus and measles, helping to prevent disease.

22 Feb 2023

New model contributes to the understanding of huge variety of genome sizes in nature

A new model developed at Tel Aviv University offers a possible solution to the scientific question of why neutral sequences, sometimes referred to as "junk DNA", are not eliminated from the genome of living creatures in nature and continue to exist within it even millions of years later.

22 Feb 2023

Study links obesity with 21 Alzheimer's disease-related genes

In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer's disease-related genes, providing a potential mechanistic explanation for why Alzheimer's is sometimes more frequent among adults who experienced obesity in midlife.

22 Feb 2023

Monitoring the presence of bovine meat and milk factor protein expression may help identify people at risk of colorectal cancer

Bovine meat and milk factors (BMMFs) - initially identified by de Villiers et al. in 2014 - represent a class of infectious agents in beef and cow's milk that have been linked to the development of cancer.

22 Feb 2023

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

22 Feb 2023

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers assessed the impact of SARS-CoV-2 spike NTD incorporation into the RBD protein vaccine.

22 Feb 2023

Researchers explore Mediterranean diet and its health benefits in managing obesity

A review article published in the journal Experimental Gerontology describes the utility of Mediterranean diet (MedDiet) in the prevention and management of obesity.

22 Feb 2023

When cancer research turns to the immune system – the critical role of peptides and immunopeptidomics

In this interview, AZoM speaks to Rohan Thakur, the President of Life Science Mass Spectrometry at Bruker, about what the opportunities of the market are and how Bruker is planning on rising to the challenge.

From Bruker Daltonics 22 Feb 2023

Dietary polyphenols may play a role in regulating inflammatory immune responses

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

A retrovirus known as human T-cell lymphotropic virus type 1 (HTLV-1) is known to cause a number of diseases, including inflammatory diseases of the eye. Recently, researchers in Japan have investigated an antibody treatment for inflammatory eye disease in ocular cells infected with HTLV-1.

21 Feb 2023

Alternative splicing plays a role in compensating for loss of gene function

Living organisms have a knack for persisting in the face of challenges. For instance, when genes malfunction, organisms may be able to compensate by activating redundant genes with similar functions, called paralogs.

21 Feb 2023

Protein C News and Research

A network of interacting proteins created to aid drug discovery

Apolipoprotein E4 promotes the development of Alzheimer’s disease

NQO2 gene as a novel potential target in Parkinson’s disease

Study finds protein biomarkers in women with perinatal mood and anxiety disorder symptoms

UMSOM researchers unravel the molecular components involved in abdominal aneurysms

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Pathogenicity of SARS-CoV-2 viral components on human periodontal tissues and cells

Study shows antibody-dependent SARS-CoV-2 transmission and pathogenesis

Male non-drinkers who eat more vegetables and less animal fat have a lower risk of diabetes

UCI-led study uncovers how APOBEC3B protein could protect cells against RNA viruses

New model contributes to the understanding of huge variety of genome sizes in nature

Study links obesity with 21 Alzheimer's disease-related genes

Monitoring the presence of bovine meat and milk factor protein expression may help identify people at risk of colorectal cancer

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers explore Mediterranean diet and its health benefits in managing obesity

When cancer research turns to the immune system – the critical role of peptides and immunopeptidomics

Dietary polyphenols may play a role in regulating inflammatory immune responses

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

Alternative splicing plays a role in compensating for loss of gene function

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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