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Resistin protein causes high levels of bad cholesterol

Canadian scientists have discovered that a protein called resistin, secreted by fat tissue, causes high levels of "bad" cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease.

29 Oct 2012

Study demonstrates role of IRX4204 in alleviating cognitive decline in animal models of AD

New research presented in October at the 6th Neurodegenerative Conditions Research and Development Conference in San Francisco demonstrates the role of the investigational compound IRX4204 in alleviating cognitive decline in animal models of Alzheimer's disease (AD).

29 Oct 2012

Trial finds benefits in using radial approach for primary angioplasty in heart attack patients

A study found several benefits in using the radial artery in the arm as the entry point for angioplasty or percutaneous coronary intervention (PCI) compared to the femoral artery in the leg. Results of the STEMI-RADIAL trial were presented today at the 24th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium.

29 Oct 2012

AACAP honors Pittsburgh psychiatric professor with Klingenstein Third Generation Foundation award

The American Academy of Child and Adolescent Psychiatry (AACAP) is pleased to announce David A. Axelson, M.D, Assistant Professor of Psychiatry, University of Pittsburgh School of Medicine, and Western Psychiatric Institute and Clinic, and Director, Child and Adolescent Bipolar Services, Western Psychiatric Institute and Clinic, as the recipient of the Klingenstein Third Generation Foundation Award for Research in Depression or Suicide for his paper, "Course of Subthreshold Bipolar Disorder in Youth: Diagnostic Progression From Bipolar Disorder Not Otherwise Specified," published in the October 2011 issue of the Journal of the American Academy of Child and Adolescent Psychiatry.

29 Oct 2012

Research roundup: Patients' unrealistic expectations for chemo; Neighborhood may affect CPR rates; Rate hike reviews working

"To make informed decisions about whether to receive chemotherapy, patients with advanced lung or colorectal cancer need a realistic understanding of its likely benefits," the authors write. Researchers conducted comprehensive reviews of records.

29 Oct 2012

Researchers investigate unique features of arcuate neurons in the hypothalamus

Maintaining a healthy body weight may be difficult for many people, but it's reassuring to know that our brains and bodies are wired to work together to do just that-in essence, to achieve a phenomenon known as energy balance, a tight matching between the number of calories consumed versus those expended. This careful balance results from a complex interchange of neurobiological crosstalk within regions of the brain's hypothalamus, and when this "conversation" goes awry, obesity or anorexia can result.

29 Oct 2012

Older patients with COPD at increased risk for carotid artery plaque formation: Study

Older patients with chronic obstructive pulmonary disease are at increased risk for carotid artery plaque formation and for the presence of vulnerable plaques with a lipid core, according to a new study from researchers in the Netherlands.

29 Oct 2012

Study identifies genetic variations as predictors of prostate cancer-related fatigue

Researchers at Moffitt Cancer Center and the University of South Florida have found that men with prostate cancer who receive androgen deprivation therapy may predictably suffer from fatigue if they have single nucleotide polymorphisms in three pro-inflammatory genes. The discovery highlights the importance of personalized medicine, in which therapies are tailored to a patient's genetic profile.

29 Oct 2012

Skin safety tips to avoid allergies during Halloween

The effects of using face paints for Halloween can be scary, says Sofia Chaudhry, M.D., assistant professor of dermatology at Saint Louis University.

29 Oct 2012

Study describes how Dbr1 gene halts toxic buildup of TDP-43-a protein

Scientists at the Gladstone Institutes and the Stanford University School of Medicine have discovered how modifying a gene halts the toxic buildup of a protein found in nerve cells. These findings point to a potential new tactic for treating a variety of neurodegenerative conditions, including amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease)-a fatal disease for which there is no cure.

29 Oct 2012

ADHD linked to altered neural activation in bipolar patients

Bipolar disorder patients with and without comorbid attention-deficit hyperactivity disorder differ in neural activation patterns during response inhibition, results from a US study show.

26 Oct 2012

FDA approves 'first non-surgical treatment' for vitreomacular adhesion

The US Food and Drug Administration reports the approval of ocriplasmin for the treatment of symptomatic vitreomacular adhesion.

26 Oct 2012

Imaging-based therapy benefits ‘wake-up stroke’ patients

Undertaking thrombolysis on the basis of magnetic resonance imaging findings in patients with stroke of unknown onset time may double their chances for a good outcome, say researchers.

26 Oct 2012

EU Tobacco Products Directive further delayed

The EU’s revised Tobacco Products Directive – which was set to place substantial new restrictions on tobacco companies’ promotion of cigarettes and smokeless tobacco, including banning “e-cigarettes” – is dangerously close to stalling, and “further delay will raise serious questions about whose interest the EU Commission is promoting”, according to the authors of a Comment, published in The Lancet.

26 Oct 2012

Hundreds of health professionals to make their voices heard on a range of public health issues

Hundreds of health professionals will descend upon Sydney next week to make their voice heard on a range of public health issues (October 31 – November 3).

26 Oct 2012

Intracoronary and IV abciximab during angioplasty do not result in differences in myocardial damage

A study confirmed no differences in various measures of heart damage, according to cardiac magnetic resonance (MRI) imaging, in patients receiving the anti-clotting medication abxicimab directly into the heart (intracoronary) compared to those receiving it intravenously (IV).

26 Oct 2012

Loyola and Hines VA announce accreditation of Dermatopathology Fellowship Program by ACGME

Loyola University Chicago Stritch School of Medicine and the Edward Hines, Jr. VA Hospital Pathology and Dermatology Divisions have announced the accreditation of a Dermatopathology Fellowship Program by the Accreditation Council for Graduate Medical Education (ACGME).

26 Oct 2012

Researchers figure out 3D shape of promising TB drug target

Researchers at Johns Hopkins have figured out the three-dimensional shape of the protein responsible for creating unique bonds within the cell wall of the bacteria that cause tuberculosis. The bonds make the bacteria resistant to currently available drug therapies, contributing to the alarming rise of these super-bacteria throughout the world.

26 Oct 2012

Contaminated drug passed lab test

Products from the Massachusetts pharmacy linked to the deadly meningitis outbreak passed a lab test in May, reports The Wall Street Journal. In addition, the pharmacy dodged a reprimand by Massachusetts regulators in 2004 after protesting it would be "fatal to the business." The company's founders come under scrutiny by media outlets as more people file lawsuits.

26 Oct 2012

Allergies and hygiene: an interview with Sally Bloomfield

Allergies occur when the body overreacts to substances in our environment, such as pollen, dust mites and so forth. What happens is that when we are exposed to these potential threats, the immune system should react, deal with it, and then shut down.

26 Oct 2012

Medicine News and Research

Resistin protein causes high levels of bad cholesterol

Study demonstrates role of IRX4204 in alleviating cognitive decline in animal models of AD

Trial finds benefits in using radial approach for primary angioplasty in heart attack patients

AACAP honors Pittsburgh psychiatric professor with Klingenstein Third Generation Foundation award

Research roundup: Patients' unrealistic expectations for chemo; Neighborhood may affect CPR rates; Rate hike reviews working

Researchers investigate unique features of arcuate neurons in the hypothalamus

Older patients with COPD at increased risk for carotid artery plaque formation: Study

Study identifies genetic variations as predictors of prostate cancer-related fatigue

Skin safety tips to avoid allergies during Halloween

Study describes how Dbr1 gene halts toxic buildup of TDP-43-a protein

ADHD linked to altered neural activation in bipolar patients

FDA approves 'first non-surgical treatment' for vitreomacular adhesion

Imaging-based therapy benefits ‘wake-up stroke’ patients

EU Tobacco Products Directive further delayed

Hundreds of health professionals to make their voices heard on a range of public health issues

Intracoronary and IV abciximab during angioplasty do not result in differences in myocardial damage

Loyola and Hines VA announce accreditation of Dermatopathology Fellowship Program by ACGME

Researchers figure out 3D shape of promising TB drug target

Contaminated drug passed lab test

Allergies and hygiene: an interview with Sally Bloomfield

Everything there is to know about biosimilars eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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