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Ancestry could simplify searches for harmful mutations

Explosive advancement in human genome sequencing opens new possibilities for identifying the genetic roots of certain diseases and finding cures. However, so many variations among individual genomes exist that identifying mutations responsible for a specific disease has in many cases proven an insurmountable challenge.

26 Oct 2012

Viewpoints: Medicare provider cuts 'won't work'; A 'pamphlet isn't a plan'

Once the presidential election is over, Congress will try to address the Medicare cost shortfall one way or another. They will almost certainly consider a method that is guaranteed to fail: Medicare rate cuts for doctors and hospitals. It's been tried before, most notably as part of the 1997 Balanced Budget Act. Not once since the BBA required annual physician rate cuts have those cuts been implemented, leading every year to the predictable and depressing final-hours "doc fix" vote.

26 Oct 2012

Resveratrol does not appear to offer metabolic benefits in healthy women

Resveratrol, an ingredient in red wine thought to improve insulin sensitivity, reduce risk of heart disease and increase longevity, does not appear to offer these benefits in healthy women, new research at Washington University School of Medicine in St. Louis indicates.

26 Oct 2012

HSS announces opening of new Lerner Children's Pavilion

The new Pavilion within the #1 hospital for orthopedics in the country affirms HSS' longstanding commitment to championing children and caring for their musculoskeletal conditions.

26 Oct 2012

Medical practice evolves: Prescribing habits, doc-patient relationship, health law changes

A push to treat chronic pain and financial disincentives for treating addiction may pressure clinicians into prescribing opioids for patients who are already addicted, a researcher suggested.

26 Oct 2012

Zebrafish model can test unique individual genetic differences in humans

The zebrafish is a potential tool for testing one class of unique individual genetic differences found in humans, and may yield information helpful for the emerging field of personalized medicine, according to a team led by Penn State College of Medicine scientists. The differences, or mutations, in question create minor changes in amino acids -- the building blocks of DNA -- from person to person.

26 Oct 2012

GW SMHS to host health expo for people with intellectual and developmental disabilities

The George Washington University (GW) School of Medicine and Health Sciences' (SMHS) Doctoral Physical Therapy program and Physician Assistant program will be hosting a health and wellness expo for persons living with intellectual and developmental disabilities (ages 16 and up). Caregivers are encouraged to attend, as well.

26 Oct 2012

NHCS researchers develop human heart cell model of ARVC

Researchers at the National Heart Centre Singapore (NHCS) have successfully created a human heart cell model of arrhythmogenic right ventricular cardiomyopathy (ARVC), an inherited heart muscle disorder which puts one at high risk of developing life-threatening arrhythmias and sudden cardiac death.

26 Oct 2012

Differing opinions about AMFm 'unlikely to be resolved' after Global Fund decision on program's future

In her "Global Health Blog," Guardian health editor Sarah Boseley examines the Affordable Medicines Facility-malaria (AMFm), "which aims to enable countries to increase the provision of affordable artemisinin combination therapies (ACTs) through not only the public sector but also the private sector and [non-governmental organizations (NGOs)]."

26 Oct 2012

Human Gene Therapy articles describe two novel anti-tumor therapies

Targeted T-cells can seek out and destroy tumor cells that carry specific antigen markers. Two novel anti-tumor therapies that take advantage of this T-cell response are described in articles published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

26 Oct 2012

NewYork-Presbyterian/Columbia participates in Symplicity system trial for hypertension

Patients with hypertension whose blood pressure cannot be brought down to safe levels despite taking three or more medications may have some relief coming their way. An innovative, first-of-its-kind clinical trial for a device representing a dramatic shift in treatment approaches for the toughest-to-treat patients is currently being conducted at NewYork-Presbyterian Hospital.

From Medtronic 26 Oct 2012

CTCtrap can capture circulating tumour cells in cancer patients

The 7.5 millilitres of blood contained in a standard sample tube is not nearly enough to detect circulating tumour cells (CTCs) in the blood of patients with metastatic breast cancer, prostate cancer, or colorectal cancer with a high enough degree of reliability. These CTCs are the cause of metastases in cancer patients. If they can be effectively characterized, it is possible to arrive at a prognosis and to determine the most effective course of treatment.

26 Oct 2012

PFO closure with investigational device may prevent cryptogenic ischemic stroke

A clinical trial indicates that using an investigational medical device to close a PFO, or "hole in the heart," may be superior to medical management alone in the prevention of a repeated stroke.

26 Oct 2012

World Prematurity Day: Nov. 17

This meeting organised in Paris from the 25th to the 27th of October, will be the opportunity to mark the end of inclusions for a cohort of over 8000 very preterm infants and to provide feedback on preliminary results of the project, launched in 2011.

26 Oct 2012

Study defines complexity of underlying mutations responsible for pancreatic cancers

A large-scale study that defines the complexity of underlying mutations responsible for pancreatic cancers in more than 100 patients was published in Nature today.

26 Oct 2012

Study identifies essential mechanism that regulates calcium flow into mitochondria

Most healthy cells rely on a complicated process to produce the fuel ATP. Knowing how ATP is produced by the cell's energy storehouse - the mitochondria -- is important for understanding a cell's normal state, as well as what happens when things go wrong, for example in cancer, cardiovascular disease, neurodegeneration, and many rare disorders of the mitochondria.

26 Oct 2012

New study offers hope for lonely older adults at increased risk of health problems

Always look on the bright side of life. Thanks to a new study from Concordia University, this catchy refrain offers a prescription for staying healthy during one's golden years.

26 Oct 2012

UWCCC enrolls first patient in Phase 1-2 PET imaging trial of LIGHT for solid tumors

Novelos Therapeutics, Inc., a pharmaceutical company developing novel drugs for the treatment and diagnosis of cancer, today announced that the University of Wisconsin Carbone Cancer Center, a leading oncology research institution, has enrolled the first patient in a Phase 1-2 positron emission tomography (PET) imaging trial of I-124-CLR1404, a cancer-targeted PET imaging agent, in patients with nine solid tumor types, including triple negative breast, soft tissue sarcoma, colorectal, gastric, esophageal, prostate, ovarian, pancreatic and head & neck cancer.

26 Oct 2012

Jefferson researchers to investigate mechanisms involved in nephrogenic systemic fibrosis

Researchers at the Jefferson Institute of Molecular Medicine were awarded almost $384,000 by the National Institutes of Health to investigate the mechanisms involved in the development of a serious and sometimes fatal disease, known as Nephrogenic Systemic Fibrosis, a rare skin disorder linked to Gadolinium-based contrast agents used in magnetic resonance (MRI and MRA) studies.

26 Oct 2012

Omega-3 fatty acid can enhance cognition in highly functional young individuals

While Omega-3 essential fatty acids-found in foods like wild fish and grass-fed livestock-are necessary for human body functioning, their effects on the working memory of healthy young adults have not been studied until now.

26 Oct 2012

Medicine News and Research

Ancestry could simplify searches for harmful mutations

Viewpoints: Medicare provider cuts 'won't work'; A 'pamphlet isn't a plan'

Resveratrol does not appear to offer metabolic benefits in healthy women

HSS announces opening of new Lerner Children's Pavilion

Medical practice evolves: Prescribing habits, doc-patient relationship, health law changes

Zebrafish model can test unique individual genetic differences in humans

GW SMHS to host health expo for people with intellectual and developmental disabilities

NHCS researchers develop human heart cell model of ARVC

Differing opinions about AMFm 'unlikely to be resolved' after Global Fund decision on program's future

Human Gene Therapy articles describe two novel anti-tumor therapies

NewYork-Presbyterian/Columbia participates in Symplicity system trial for hypertension

CTCtrap can capture circulating tumour cells in cancer patients

PFO closure with investigational device may prevent cryptogenic ischemic stroke

World Prematurity Day: Nov. 17

Study defines complexity of underlying mutations responsible for pancreatic cancers

Study identifies essential mechanism that regulates calcium flow into mitochondria

New study offers hope for lonely older adults at increased risk of health problems

UWCCC enrolls first patient in Phase 1-2 PET imaging trial of LIGHT for solid tumors

Jefferson researchers to investigate mechanisms involved in nephrogenic systemic fibrosis

Omega-3 fatty acid can enhance cognition in highly functional young individuals

Everything there is to know about biosimilars eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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