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Glowing mice could mark major step forward for new gene therapy

Timothy Blake, a postdoctoral fellow in the Waymouth lab, was hard at work on a fantastical interdisciplinary experiment. He and his fellow researchers were refining compounds that would carry instructions for assembling the protein that makes fireflies light up and deliver them into the cells of an anesthetized mouse. If their technique worked, the mouse would glow in the dark.

16 Feb 2017

Single high-fat meal can change energy metabolism of the liver, study finds

The global proliferation of overweight and obese people and people with type 2 diabetes is often associated with the consumption of saturated fats.

16 Feb 2017

Uflex creates major breakthrough in cold formed pharmaceutical packaging industry

Conventionally Polyvinyl Chloride (PVC) and Bi-axially Oriented Polyamide, BOPA (commonly known as BON) films have been extensively used in cold formed pharma packaging industry. A typical Alu–Alu blister laminate comprises three layers i.e. 25 micron BOPA/ 60 micron soft aluminium foil / 60 micron PVC.

16 Feb 2017

Salk scientists use mRNA to successfully treat hemophilia B in mice

FedEx, UPS, DHL--when it comes to sending packages, choices abound. But the most important delivery service you may not have heard of mRNA.

16 Feb 2017

Signals from fat cells may aid in diagnostics for metabolic conditions

Fat cells are not simply big blobs of lipid quietly standingby in the body--instead, they send out hormones and other signaling proteins that affect many types of tissues.

15 Feb 2017

Changes in size of mitochondria in subset of brain cells could be key to maintaining blood sugar

Keeping blood sugar levels within a safe range is key to managing both type 1 and type 2 diabetes. In a new finding that could lead to fewer complications for diabetes patients, Yale School of Medicine researchers have found that changes in the size of mitochondria in a small subset of brain cells play a crucial role in safely maintaining blood sugar levels.

15 Feb 2017

Naturally occurring protein shows promise as biocontrol weapon against schistosomiasis

A naturally occurring protein has been discovered that shows promise as a biocontrol weapon against schistosomiasis, one of the world's most prevalent parasitic diseases, Oregon State University researchers reported today in a new study.

15 Feb 2017

Weight gain over course of life can increase risk of developing oesophageal and stomach cancers

People who are overweight in their twenties and become obese later in life may be three times more likely to develop cancer of either the oesophagus (food pipe) or upper stomach, according to a study published in the British Journal of Cancer today (Wednesday).

15 Feb 2017

Study provides new insight into causes of rare metabolic disorder

Just before Rare Disease Day 2017, a study from the Monell Center and collaborating institutions provides new insight into the causes of trimethylaminura, a genetically-transmitted metabolic disorder that leads to accumulation of a chemical that smells like rotting fish.

14 Feb 2017

Children born of fathers exposed to nicotine inherit enhanced chemical tolerance, study shows

A father's nicotine use may have a significant impact on children's risk of some diseases. In a study published in the online biomedical sciences journal eLife, Oliver J. Rando, MD, PhD, and colleagues at UMass Medical School, demonstrate that mice born of fathers who are habitually exposed to nicotine inherit enhanced chemical tolerance and drug clearance abilities.

14 Feb 2017

Ten steps for a healthy pregnancy

The Ten Steps for a Healthy Pregnancy, aims to offer mums-to-be essential advice to adopt good habits for healthy growth and development for both mum and baby.

14 Feb 2017

Dietary fructose consumption may increase risk for NASH in children and adolescents

Recent research suggests that dietary fructose intake may increase serum uric acid concentrations and that both uric acid concentration and fructose consumption may be increased in individuals with non-alcoholic fatty liver disease.

14 Feb 2017

Long-term use of testosterone therapy in hypogonadal men may reduce risk of death from CV disease

Despite the continued controversy surrounding the use of testosterone in men who have testosterone deficiency (hypogonadism), a new study has found that long-term use of testosterone therapy not only improves vigor and vitality, but may reduce the risk of death due to cardiovascular (CV) disease.

13 Feb 2017

Researchers use liquid biopsies, tiny experimental device to predict cancer spread and hasten diagnosis

A team of investigators from Cedars-Sinai and UCLA is using a new blood-analysis technique and tiny experimental device to help physicians predict which cancers are likely to spread by identifying and characterizing tumor cells circulating through the blood.

13 Feb 2017

Reprogramming liver cells to become pancreatic cells may help diabetic patients

It is now possible to reprogram cells from the liver into the precursor cells that give rise to the pancreas by altering the activity of a single gene.

13 Feb 2017

New ‘MAGIC algorithm’ can predict transplant patient’s risk of developing graft-versus-host disease

Researchers at Mount Sinai Health System have discovered a way to predict whether blood cancer patients who received a bone marrow transplant will develop graft-versus-host disease, a common and often lethal complication, according to a study published in JCI Insight.

9 Feb 2017

Sickest children can successfully undergo liver transplantation with advances in critical care

Advancements in critical care make it possible for even the sickest children to successfully undergo liver transplantation.

7 Feb 2017

Study could provide novel therapeutic approach for preventing severe jaundice in newborn babies

For many newborn babies, an enzyme that breaks down the molecule bilirubin doesn't activate right away. The resulting bilirubin buildup can lead to jaundice, a typically harmless condition that causes a baby's skin to temporarily appear yellow.

6 Feb 2017

Researchers develop ingestible devices that derive long-term power from stomach and small intestine

A research team led by scientists from Brigham and Women's Hospital and the Massachusetts Institute of Technology has developed a set of ingestible devices that draw energy from fluids in the stomach and the small intestine, and can provide power for nearly a week.

6 Feb 2017

Researchers identify new mechanism that protects from bacterial infections

An international team led by the University if Barcelona has identified a new antibacterial mechanism that protects macrophages - defense cells in the immune system- from the infection of the bacteria Salmonella enterica serovar Typhimurium, a pathogen associated with several gastrointestinal diseases.

2 Feb 2017

Liver News and Research

Glowing mice could mark major step forward for new gene therapy

Single high-fat meal can change energy metabolism of the liver, study finds

Uflex creates major breakthrough in cold formed pharmaceutical packaging industry

Salk scientists use mRNA to successfully treat hemophilia B in mice

Signals from fat cells may aid in diagnostics for metabolic conditions

Changes in size of mitochondria in subset of brain cells could be key to maintaining blood sugar

Naturally occurring protein shows promise as biocontrol weapon against schistosomiasis

Weight gain over course of life can increase risk of developing oesophageal and stomach cancers

Study provides new insight into causes of rare metabolic disorder

Children born of fathers exposed to nicotine inherit enhanced chemical tolerance, study shows

Ten steps for a healthy pregnancy

Dietary fructose consumption may increase risk for NASH in children and adolescents

Long-term use of testosterone therapy in hypogonadal men may reduce risk of death from CV disease

Researchers use liquid biopsies, tiny experimental device to predict cancer spread and hasten diagnosis

Reprogramming liver cells to become pancreatic cells may help diabetic patients

New ‘MAGIC algorithm’ can predict transplant patient’s risk of developing graft-versus-host disease

Sickest children can successfully undergo liver transplantation with advances in critical care

Study could provide novel therapeutic approach for preventing severe jaundice in newborn babies

Researchers develop ingestible devices that derive long-term power from stomach and small intestine

Researchers identify new mechanism that protects from bacterial infections

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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