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UChicago researchers awarded NIH grants to develop novel medications for sleep apnea, asthma

Two research teams based at the University of Chicago have received prestigious grants from the National Institutes of Health to develop novel medications to treat sleep apnea and asthma.

21 Jan 2015

LUME-Lung 1 shows QoL, symptoms benefits

LUME-Lung 1 trial patients’ reports of symptoms and health-related quality of life support the use of second-line nintedanib for the treatment of advanced non-small-cell lung cancer.

20 Jan 2015

MET amplified in NSCLC irrespective of type, genetic background

A third of non-small-cell lung cancers show low- to high-level amplification of the MET gene, according to a German study, with no significant difference in frequency across different types of cancer and genetic backgrounds.

20 Jan 2015

Rare, complex EGFR mutations adversely affect EGFR–TKI treatment outcomes

Individuals with advanced non-small-cell lung cancer who have rare or complex epidermal growth factor receptor mutations have inferior outcomes in response to EGFR–tyrosine kinase inhibitor treatment compared with those with common mutations, research indicates.

20 Jan 2015

St. Luke’s offers Frameless Stereotactic Radiosurgery for treatment of brain tumors

Some treatments for brain and spine tumors traditionally have involved restraining a patient with a heavy immobilization device and pins that pierce the skin and embed into the skull to ensure the accuracy and precision of a treatment. Doctors say the pins can add considerable anxiety.

20 Jan 2015

FDA removes partial clinical hold on CytRx's aldoxorubicin clinical trials

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today announced that the United States Food and Drug Administration has removed the partial clinical hold on the Company's aldoxorubicin clinical trials.

20 Jan 2015

Joining a walking group helps boost overall health

Joining a walking group is one of the best and easiest ways to boost overall health, with virtually no side effects, suggests an analysis of the available evidence, published online in the British Journal of Sports Medicine.

20 Jan 2015

Researchers identify novel signaling pathway that triggers allergic asthma response

Researchers at the University of California, San Diego School of Medicine, with collaborators in Korea and Scotland, have identified a novel signaling pathway critical to the immune response of cells associated with the initiation of allergic asthma.

20 Jan 2015

Patients who receive lungs from heavy drinkers more likely to develop severe primary graft dysfunction

Lung transplant patients who receive lungs from heavy drinkers are nearly nine times more likely to experience a life-threatening complication called primary graft dysfunction, a Loyola University Medical Center study has found.

20 Jan 2015

Regular outdoor walking in groups boosts health, reduces life-threatening conditions

Risk of stroke, coronary heart disease, depression and other life-threatening conditions can be reduced through regular outdoor walking in groups, according to research from the University of East Anglia.

19 Jan 2015

WHO calls for urgent action to reduce premature deaths from noncommunicable diseases

Urgent government action is needed to meet global targets to reduce the burden of noncommunicable diseases (NCDs), and prevent the annual toll of 16 million people dying prematurely - before the age of 70 - from heart and lung diseases, stroke, cancer and diabetes, according to a new WHO report.

19 Jan 2015

MD Anderson honored with top science and technology award in China

The University of Texas MD Anderson Cancer Center was presented the People's Republic of China International Science and Technology Cooperation Award at a ceremony held Jan. 9 at Beijing's Great Hall of the People.

16 Jan 2015

Concentric remodelling preserves right ventricular function in PAH

Systolic function is better preserved in patients with idiopathic pulmonary arterial hypertension if they have a higher right ventricle mass-to-volume ratio, research shows.

16 Jan 2015

Peripheral muscles weakened in PAH patients

Patients with pulmonary arterial hypertension have peripheral muscle weakness that is independent of impairments in their respiratory muscles, research shows.

16 Jan 2015

CT measures can refine PAH prognosis

Structural features identifiable on computed tomography pulmonary angiography can provide prognostic information for patients with pulmonary arterial hypertension, say UK researchers.

16 Jan 2015

Early estimates indicate flu vaccine is providing little protection in US

Each year the Centers for Disease Control and Prevention (CDC) undertake flu vaccine effectiveness studies. Early estimates for the current season indicate that those people (all ages) who had the flu vaccine were only 23% less likely to have to go to the doctor because of flu (influenza).

16 Jan 2015

New research helps explain why pancreatic cancer is so lethal

New research from the University of Michigan Comprehensive Cancer Center helps explain why pancreatic cancer is so lethal, with fewer than a third of patients surviving even early stage disease.

16 Jan 2015

Leading microbiologist warns of killer fungi’s increasing threat

A leading microbiologist has warned of the increasing threat that killer fungi poses to humans and the environment.

15 Jan 2015

Changes in health limitations, chronic conditions can predict mortgage distress

The mortgage strain of American home ownership can lead to poor health but a new study finds that the inverse may also be true-- changes in health can serve as a predictor to mortgage distress.

15 Jan 2015

Scientists identify first genetic marker linked to severe neurological toxicity

Paclitaxel is a chemotherapeutic drug that has been shown to be highly effective when treating solid tumours, such as breast, ovarian and lung tumours. However, its use frequently causes peripheral neuropathies, neurological problems that affect the vast majority of patients.

15 Jan 2015