Fatigue News and Research

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FDA recommends approval of the investigational anti-HIV drug tipranavir

Boehringer Ingelheim today announced that the U.S. Food and Drug Administration's (FDA) Antiviral Drugs Advisory Committee recommended the approval of the investigational anti-HIV drug tipranavir (11-3). Tipranavir is a non-peptidic protease inhibitor that requires boosting with low-dose ritonavir and must be used in combination with other antiretroviral agents.

20 May 2005

Metabolic syndrome linked to testosterone deficiency

Among men studied, those with a history of diabetes, hypertension or hyperlipidemia have a higher prevalence of hypogonadism, according to new research issued today at the American Association of Clinical Endocrinologists (AACE) Fourteenth Annual Meeting and Clinical Congress.

18 May 2005

Testosterone appears to benefit, not harm, cardiovascular health of middle-aged men

Although men suffer more coronary heart disease than women, the blame should not be placed on testosterone, according to a new study in the May 17, 2005, issue of the Journal of the American College of Cardiology.

18 May 2005

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

A unique, targeted anti-cancer drug appears to show promise against neuroendocrine tumors-stubborn cancers that have traditionally responded poorly to chemotherapy, according to research findings announced at the 2005 Annual Meeting of the American Society of Clinical Oncology (ASCO).

17 May 2005

Bevacizumab (Avastin) combined with low-dose chemotherapy slows ovarian cancer

A targeted cancer drug given with low-dose chemotherapy shrank ovarian tumors and slowed progression of ovarian cancer in patients with recurrent disease, according to research findings presented by Agustin Garcia, M.D., principal investigator of the study and Director of Breast Cancer Research at the Women's Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center.

16 May 2005

Disabling gene defuses rheumatoid arthritis in mice

Scientists studying mice have identified a gene that allows immune cells known as neutrophils to protect themselves from the inflammatory chemicals they secrete.

16 May 2005

Social anxiety disorder patients may be avoiding their doctor

Patients with social anxiety disorder are less likely to visit their primary care doctors than people with other psychiatric disorders like depression, or patients without mental health disorders, according to new research in the journal General Hospital Psychiatry.

16 May 2005

New anticancer drug SU11248 shows continued response for patients with late-stage kidney cancer

Recent studies of a new anticancer drug show continued response for patients with late-stage kidney cancer. Robert Motzer, MD, attending physician at Memorial Sloan-Kettering Cancer Center (MSKCC), reported a response rate of 40 percent in patients with metastatic (advanced) renal cell (kidney) cancer who received SU11248 in second-line therapy.

15 May 2005

Work fatigue and working overtime are associated with weight gain

Based on a recent study, work fatigue, working overtime, job demands and dissatisfaction in combining paid work and family life are associated with weight gain.

12 May 2005

Call for "ring-fenced" funds for research into Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (ME/CFS)

The medical research charity, MERGE (ME Research Group) is calling for the ring fencing of resources for biomedical research into ME/CFS.

11 May 2005

Adolescents who don't get enough sleep might be jeopardizing their athletic performance,

"Young people live in nearly a constant state of chronic insufficient sleep," says Carskadon, "and adolescents who don't get enough sleep on a regular basis are extremely impaired in the morning."

10 May 2005

Doctors challenged to speed up diagnosis of M.E./Chronic Fatigue Syndrome

A new report launched to mark the start of M.E. Awareness Week 2005 calls on doctors to speed up the diagnosis of M.E./Chronic Fatigue Syndrome and so reduce the number of patients declining into long term ill health and disability. M.E. Diagnosis: Delay Harms Health is backed by an alliance of six national charities frustrated that delays in diagnosis are continuing to impair improvement or recovery in people with M.E.

8 May 2005

Physician assisted suicide and why patients are motivated to seek death

Patients motivated to seek a doctor for their death wish did so after a deliberative and thoughtful process rather than on impulse, according to a research study published in the Journal of General Internal Medicine .

5 May 2005

Polio alert after Indonesian child is stricken

After an 18-month-old boy was diagnosed with polio, Australian parents planning holidays in Indonesia have been warned to ensure babies and toddlers have been vaccinated for polio.

3 May 2005

Whooping cough makes a comeback

The latest comeback in the health arena is whooping cough and experts are sufficiently concerned for the US government to approve the first whooping cough booster shot meant just for adolescents. The shot will be added to a booster shot against two other diseases, tetanus and diphtheria, that children already get sometime between ages 10 and 18.

3 May 2005

Promising results from study of Pirfenidone in idiopathic pulmonary fibrosis (IPF) patients

InterMune today announced that the American Journal of Respiratory and Critical Care Medicine (AJRCCM) published results from a double-blind, randomized, placebo-controlled Phase II trial evaluating pirfenidone for the treatment of patients with idiopathic pulmonary fibrosis (IPF).

2 May 2005

Use of agricultural insecticides linked to lasting neurological problems for farmers

New research shows that farmers who used agricultural insecticides experienced increased neurological symptoms, even when they were no longer using the products. Data from18,782 North Carolina and Iowa farmers linked use of insecticides, including organophosphates and organochlorines, to reports of reoccurring headaches, fatigue, insomnia, dizziness, nausea, hand tremors, numbness and other neurological symptoms. Some of the insecticides addressed by the study are still on the market, but some, including DDT, have been banned or restricted.

1 May 2005

Schistosomiasis has a greater effect than previosly thought

Schistosomiasis, an infection caused by a parasitic worm, affects more than 200 million worldwide, most of them in Africa and many health workers believe the disabling effects of schistosomiasis have never been adequately quantified.

1 May 2005

Ginkgo beneficial for multiple sclerosis symptoms

When it comes to her health, Janice Winfield of Portland, Ore., does her research. That's why the stay-at-home mom, who was diagnosed with multiple sclerosis in July 2000, was willing to turn to popular, over-the-counter herbal supplements like ginkgo biloba to deal with memory problems, fatigue and occasional muscle pain.

27 Apr 2005

Brits fed up with eating advice

In a study of 988 adults, by consumer analyst Mintel, it was found that almost half of Britons are tired of healthy eating campaigners telling them how to change their diet

27 Apr 2005

Fatigue News and Research

FDA recommends approval of the investigational anti-HIV drug tipranavir

Metabolic syndrome linked to testosterone deficiency

Testosterone appears to benefit, not harm, cardiovascular health of middle-aged men

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

Bevacizumab (Avastin) combined with low-dose chemotherapy slows ovarian cancer

Disabling gene defuses rheumatoid arthritis in mice

Social anxiety disorder patients may be avoiding their doctor

New anticancer drug SU11248 shows continued response for patients with late-stage kidney cancer

Work fatigue and working overtime are associated with weight gain

Call for "ring-fenced" funds for research into Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (ME/CFS)

Adolescents who don't get enough sleep might be jeopardizing their athletic performance,

Doctors challenged to speed up diagnosis of M.E./Chronic Fatigue Syndrome

Physician assisted suicide and why patients are motivated to seek death

Polio alert after Indonesian child is stricken

Whooping cough makes a comeback

Promising results from study of Pirfenidone in idiopathic pulmonary fibrosis (IPF) patients

Use of agricultural insecticides linked to lasting neurological problems for farmers

Schistosomiasis has a greater effect than previosly thought

Ginkgo beneficial for multiple sclerosis symptoms

Brits fed up with eating advice

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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