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EKF Diagnostics highlighting cancer molecular diagnostics products at ASCO 2015

EKF subsidiary, Selah Genomics’ newly introduced PrecisionPath™ next generation sequencing (NGS) technology cancer test will be a key focus on Booth #19141...

From EKF Diagnostics 28 May 2015

Progression of different types of breast cancer influenced differently by tumor microenvironment

Our environment can have a major impact on how we develop, and it turns out it's no different for cancer cells. In work published today in Neoplasia, a team of researchers led by Associate Professor Mikala Egeblad at Cold Spring Harbor Laboratory found that two different mouse models of breast cancer progressed differently based on characteristics of the tumor microenvironment - the area of tissue in which the tumor is embedded.

28 May 2015

Aldosterone/renin ratio reliable diagnostic tool in infant primary hypoaldosteronism

The ratio of aldosterone to renin in plasma is a reliable indicator of primary hypoaldosteronism in newborns and infants, say researchers.

27 May 2015

Researchers use animal models to study how dysfunction of genes contributes to ASD risk

Autism Spectrum Disorder (ASD) is a neurological condition that affects approximately two percent of people around the world. Although several genes have been linked to multiple concurring conditions of ASD, the process that explains how specific genetic variants lead to behaviors characteristic of the disorder remains elusive.

27 May 2015

Not feeling pain due to genetic mutation may not be a blessing

A rare congenital genetic mutation means that those affected do not feel pain. However, what seems, at first sight, to be a blessing, can have serious consequences. It means that injuries or diseases can go undetected for a long time. The affected gene was identified by an international research team from MedUni Vienna, the University of Munich and the University of Cambridge.

27 May 2015

Clinical utility data for Guardant360 platform to be presented at ASCO 2015

Guardant Health today announced that five abstracts submitted by the University of California, San Francisco; University of California, San Diego; and MD Anderson highlighting the performance and clinical utility of Guardant360 have been accepted for oral and poster presentations at the 2015 American Society of Clinical Oncology Annual Meeting in Chicago, May 29-June 2.

27 May 2015

UC San Diego Health System designated as Center of Excellence for Huntington's disease

The Huntington's Disease Clinical Research Center at UC San Diego Health System has been designated a Center of Excellence by the Huntington's Disease Society of America. UC San Diego was one of only 29 centers nationwide to receive this prestigious designation, which recognizes centers for their elite multidisciplinary approach to Huntington's disease care and research.

27 May 2015

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

An international team including scientists from Albert Einstein College of Medicine of Yeshiva University and the U.S. Army Medical Research Institute of Infectious Diseases has identified the molecular "lock" that the deadly Ebola virus must pick to gain entry to cells.

27 May 2015

Removing accumulated mutant p53 protein regresses tumors, increases cancer survival

Removing accumulated mutant p53 protein from a cancer model showed that tumors regress significantly and survival increases. This finding, by an international team of cancer researchers led by Ute Moll, MD, Professor of Pathology at Stony Brook University School of Medicine, is reported in a paper published advanced online May 25 in Nature.

26 May 2015

Researchers identify six mRNA isoforms that could be used to diagnose early-stage ovarian cancer

Ovarian cancer is notoriously difficult to diagnose and treat, making it an especially fatal disease. Researchers at University of California, San Diego School of Medicine and Moores Cancer Center have now identified six mRNA isoforms (bits of genetic material) produced by ovarian cancer cells but not normal cells, opening up the possibility that they could be used to diagnose early-stage ovarian cancer.

26 May 2015

Researchers discover new gene subgroup that drives prostate cancer

Prostate cancer researchers have drawn a molecular portrait that provides the first complete picture of localized, multi-focal disease within the prostate and also unveils a new gene subgroup driving it.

26 May 2015

Essential fatty acids play crucial role in human brain growth and function

New research conducted in a rural community in Pakistan highlights the crucial role that essential fatty acids play in human brain growth and function.

26 May 2015

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that exhibits the symptoms and neurodegeneration associated with the most common genetic forms of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), both of which are caused by a mutation in the a gene called C9ORF72.

24 May 2015

Scientists uncover role of HTRA3 protease in Cockayne syndrome

Scientists from the Institut Pasteur and CNRS, in collaboration with scientists from the Institut Gustave Roussy and CEA, have succeeded in restoring normal activity in cells isolated from patients with the premature aging disease Cockayne syndrome. They have uncovered the role played in these cells by an enzyme, the HTRA3 protease.

22 May 2015

Clinical genomic sequencing could impact treatment decisions in advanced prostate cancer patients

An international collaboration of researchers are advancing precision medicine to men with advanced prostate cancer.

22 May 2015

DF/BWCC introduces new website to provide information about precision cancer medicine

Precision cancer medicine - diagnosis and treatment based on the genetic abnormalities of a specific tumor - is playing an ever-larger role in cancer care. The field got a boost earlier this year when President Barack Obama proposed a $215 million federal Precision Medicine Initiative with cancer as one of its priorities.

21 May 2015

Available research does not support link between chronic traumatic encephalopathy and sports

Available research does not support the contention that athletes are uniquely at risk of chronic traumatic encephalopathy (CTE) or other neurodegenerative disorders, according to a review in the June issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

21 May 2015

New research points to potential therapeutic target for treating multiple sclerosis

New research into the causes of the excessive inflammation that drives multiple sclerosis has identified a faulty "brake" within immune cells, a brake that should be controlling the inflammation. This points to a potential target for developing new therapies to treat multiple sclerosis and could have important implications for other autoimmune diseases, such as the colon disease colitis and the chronic skin condition atopic dermatitis.

20 May 2015

University of Missouri researchers identify key protein component that causes cystic fibrosis

Nearly 70,000 people worldwide are living with cystic fibrosis, a life-threatening genetic disease. There currently is no cure for the condition, but researchers from the University of Missouri have identified a key component in the protein that causes the disease. It is a finding that may lay the foundation for the development of new medications and improved therapies.

19 May 2015

Two-drug combination improves lung function in some cystic fibrosis patients

The combination of two drugs — an investigational drug used in conjunction with an already FDA-approved medication — improved lung function in patients with one form of cystic fibrosis, according to two new studies.

19 May 2015

Mutation News and Research

EKF Diagnostics highlighting cancer molecular diagnostics products at ASCO 2015

Progression of different types of breast cancer influenced differently by tumor microenvironment

Aldosterone/renin ratio reliable diagnostic tool in infant primary hypoaldosteronism

Researchers use animal models to study how dysfunction of genes contributes to ASD risk

Not feeling pain due to genetic mutation may not be a blessing

Clinical utility data for Guardant360 platform to be presented at ASCO 2015

UC San Diego Health System designated as Center of Excellence for Huntington's disease

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

Removing accumulated mutant p53 protein regresses tumors, increases cancer survival

Researchers identify six mRNA isoforms that could be used to diagnose early-stage ovarian cancer

Researchers discover new gene subgroup that drives prostate cancer

Essential fatty acids play crucial role in human brain growth and function

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Scientists uncover role of HTRA3 protease in Cockayne syndrome

Clinical genomic sequencing could impact treatment decisions in advanced prostate cancer patients

DF/BWCC introduces new website to provide information about precision cancer medicine

Available research does not support link between chronic traumatic encephalopathy and sports

New research points to potential therapeutic target for treating multiple sclerosis

University of Missouri researchers identify key protein component that causes cystic fibrosis

Two-drug combination improves lung function in some cystic fibrosis patients

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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