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Small non-coding RNAs can help predict individuals with breast cancer

Small non-coding RNAs can be used to predict if individuals have breast cancer conclude researchers who contribute to The Cancer Genome Atlas project. The results, which are published in EMBO reports, indicate that differences in the levels of specific types of non-coding RNAs can be used to distinguish between cancerous and non-cancerous tissues. These RNAs can also be used to classify cancer patients into subgroups of individuals that have different survival outcomes.

18 Feb 2014

New score ‘reliable and valid’ for neurogenic bladder dysfunction

The Neurogenic Bladder Symptom Score is both valid and reliable for assessing urinary dysfunction in people with acquired or congenital neurogenic bladder, according to a study published online in the Journal of Urology.

17 Feb 2014

New study documents frequency of EGFR mutations in lung adenocarcinoma in Asian population

Adenocarcinoma histology, female sex, never-smoking status, and Asian ethnicity have been considered the most important factors associated with EGFR mutations in non-small cell lung cancer and response to EGFR inhibitors. A recent study has found that, within the Asian population, the frequency of EGFR mutations associated with other demographic and clinical characteristics is higher than previously reported, even in patients with a history of smoking, suggesting that mutation testing should be done on a broader basis among Asian patients with advanced adenocarcinoma of the lung.

16 Feb 2014

Ario Pharma begins XEN-0501 Phase IIa study for treatment persistent cough in COPD patients

Ario Pharma Ltd, the Cambridge biopharmaceutical company developing innovative new approaches to treat respiratory disease, announced today that it has commenced a Phase IIa study of its TRPV1 antagonist, XEN-0501, for the treatment and prevention of cough in patients with chronic obstructive pulmonary disease (COPD). Persistent cough in COPD and other respiratory conditions present as a huge unmet medical need, with novel therapies urgently needed to improve the quality of life of patients.

11 Feb 2014

Researchers promote scientific and health prevention culture among national population

The Mexican enterprise "Science that breathes" is supported by the National Institutes of Respiratory Diseases and Carcinology among others.

11 Feb 2014

Researchers develop low-power wireless microsystem for hearing aids and implants

Microsystems are at the heart of portable hearing aids and implants. Now researchers are developing a miniature, low-power wireless microsystem to make these medical aids smaller, more comfortable and more efficient.

11 Feb 2014

Targacept completes patient recruitment in TC-5214 Phase 2b study for treatment of overactive bladder

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced that it has completed recruitment of patients in its Phase 2b clinical study of TC-5214 as a treatment for overactive bladder (OAB).

10 Feb 2014

Infection contributes to higher risk of stroke death among blacks

Infection is a stronger trigger of stroke death in African- Americans than in whites, a University of Michigan study shows.

9 Feb 2014

Sleep disturbances could be bipolar disorder treatment target

Both objective and subjective features of sleep differ between people with bipolar disorder who are currently euthymic and healthy controls, a case–control study has found.

7 Feb 2014

Rare and de novo mutations flesh out schizophrenia picture

Two studies in Nature show that rare disruptive and de novo mutations may contribute to the pathophysiology of schizophrenia.

6 Feb 2014

Randomized trial shows injecting anesthetic near nerve bundle reduces troublesome hot flashes

Injecting a little anesthetic near a nerve bundle in the neck cut troublesome hot flashes significantly, shows a new randomized, controlled trial published online today in Menopause, the journal of The North American Menopause Society (NAMS).

5 Feb 2014

'Invisible-risk' group has high prevalence of psychiatric symptoms

Adolescents with high media use, reduced sleep and low physical activity comprise an 'invisible-risk' group that has high prevalence of psychiatric symptoms, according to a large international study led by researchers at Karolinska Institutet. The results of the study are published in the February issue of World Psychiatry.

4 Feb 2014

Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

A team of researchers has reported a novel method for tracking CD4+ T cells in people infected with HIV. CD4+ T cells are critical for immune defense against an array of pathogens and are a primary target of HIV. In the study, researchers used a unique, replication-incompetent (defective) form of HIV identified in a patient in the early 1990s.

4 Feb 2014

New guidelines recommend screening mammography every 2 years for women ages 50 to 74

Adoption of new guidelines recommending screening mammography every two years for women ages 50 to 74 would result in breast cancer screening that is equally effective, while saving the United States $4.3 billion a year in health care costs, according to a study led by UC San Francisco.

4 Feb 2014

New article outlines different types of incontinence and treatment options

Urinary incontinence affects up to 13% of Australian men and up to 37% of Australian women. There are several types of urinary incontinence, and each has different treatment options.

3 Feb 2014

New technique helps identify shrinkage of mood-regulating brain structure in women with MS

A multicenter research team led by Cedars-Sinai neurologist Nancy Sicotte, MD, an expert in multiple sclerosis and state-of-the-art imaging techniques, used a new, automated technique to identify shrinkage of a mood-regulating brain structure in a large sample of women with MS who also have a certain type of depression.

31 Jan 2014

Psychiatrists urged to monitor metabolic changes in psychosis patients

Japanese psychiatrists are largely aware of the metabolic abnormalities that may arise from antipsychotic treatment, but most do not monitor their patients sufficiently, research shows.

30 Jan 2014

Simple hypomania checklist detects bipolar II disorder

A 15-item hypomania checklist has shown potential for differentiating bipolar disorder, particularly type II, from major depressive disorder.

30 Jan 2014

Spontaneous tumorigenic transformation of human MSCs can occur during cell culture expansion

Researchers at Erasmus University Medical Center Rotterdam, The Netherlands, led by Dr. Qiuwei Pan and Dr. Luc van der Laan, have discovered that spontaneous tumorigenic transformation of human mesenchymal stem/stromal cells (MSCs) can occur during cell culture expansion, although the frequency is relatively low and often only observed after extensive passage in culture.

30 Jan 2014

Researches analyse effectiveness of training in physical improvement of sportspeople

During his research, carried out at the NUP/UPNA-Public University of Navarre, he conducted five studies on 361 participants: four on male football players between the ages of 10 and 17, one on distance and middle-distance runners, adult men and women.

30 Jan 2014

Frequency News and Research

Small non-coding RNAs can help predict individuals with breast cancer

New score ‘reliable and valid’ for neurogenic bladder dysfunction

New study documents frequency of EGFR mutations in lung adenocarcinoma in Asian population

Ario Pharma begins XEN-0501 Phase IIa study for treatment persistent cough in COPD patients

Researchers promote scientific and health prevention culture among national population

Researchers develop low-power wireless microsystem for hearing aids and implants

Targacept completes patient recruitment in TC-5214 Phase 2b study for treatment of overactive bladder

Infection contributes to higher risk of stroke death among blacks

Sleep disturbances could be bipolar disorder treatment target

Rare and de novo mutations flesh out schizophrenia picture

Randomized trial shows injecting anesthetic near nerve bundle reduces troublesome hot flashes

'Invisible-risk' group has high prevalence of psychiatric symptoms

Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

New guidelines recommend screening mammography every 2 years for women ages 50 to 74

New article outlines different types of incontinence and treatment options

New technique helps identify shrinkage of mood-regulating brain structure in women with MS

Psychiatrists urged to monitor metabolic changes in psychosis patients

Simple hypomania checklist detects bipolar II disorder

Spontaneous tumorigenic transformation of human MSCs can occur during cell culture expansion

Researches analyse effectiveness of training in physical improvement of sportspeople

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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