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An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021

Researchers discover biomarker that could aid in early detection of high risk COVID-19 patients

Led by computational researchers from WEHI, in collaboration with The University of Queensland, Queensland University of Technology and Hospital Marcelino Champagnat in Brazil, the study used advanced spatial transcriptomic techniques to screen for genes associated with excessive inflammation in the lungs, a key indicator of severe COVID-19.

7 Dec 2021

Scientists find new way to reverse aggressive breast cancer into a less dangerous kind

Scientists at KAIST believe they may have found a way to reverse an aggressive, treatment-resistant type of breast cancer into a less dangerous kind that responds well to treatment.

7 Dec 2021

New research reveals how Europeans evolved greater resistance against anthrax

New research from the Cornell College of Veterinary Medicine has revealed how humans evolved greater resistance against anthrax multiple times during history: when they developed a diet of more ruminants, and when agricultural practices took hold.

7 Dec 2021

‘Moving molecule’ therapy for severe spinal cord injury

In this interview, News-Medical speaks to Dr. Stupp about his recent research into a therapy involving dancing molecules for the treatment of severe spinal cord injury.

7 Dec 2021

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

In a recent study conducted at Yale University, USA, scientists have investigated the immunogenicity of mRNA-based coronavirus disease 2019 (COVID-19) vaccine candidates encoding the spike proteins of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. The findings reveal that the vaccines induce robust immune responses against SARS-CoV-2 variants. The study is currently available on the bioRxiv* preprint server.

6 Dec 2021

COVID-19 severity is correlated with T cell receptor repertoire signatures

In a new study published in the bioRxiv* preprint server, researchers found that specific TCR sequences predicted the severity of coronavirus disease 2019 (COVID-19) infection. Additionally, there was evidence of increased CDR3 sequences and changes in k-mer motifs for patients with severe illness.

6 Dec 2021

Scientists find infection of sustentacular cells in the olfactory epithelium of COVID-19 patients

It is now widely known that COVID-19 is associated with the transient or long-term loss of olfaction (the sense of smell) but the mechanisms remain obscure.

6 Dec 2021

Announcing the Winners of The Scientist’s Top 10 Innovations of 2021

Each year The Scientist seeks to highlight the latest and greatest tools, technologies, and techniques to hit the life science landscape.

From Resolve Biosciences 6 Dec 2021

New therapeutic targets for the treatment and prevention of hypertension, cardiovascular diseases

Cardiovascular diseases are the leading cause of death worldwide. Although the development of these disorders is most commonly associated with lifestyle factors like obesity, increasing evidence suggests that events much earlier in one's life can also play a role.

6 Dec 2021

Gene expression related to liver metabolism altered by spaceflight

The latest findings of a series of studies on mice that examined harmful effects caused by spending time in space show that gene expression related to liver metabolism is altered in response to the space environment.

6 Dec 2021

Meth use and intimate partner violence drive exhaustion of immune cells in HIV patients

A study of HIV-positive black and Latino men who have sex with men finds the use of methamphetamine combined with intimate partner violence boosted the activity of genes that regulate the body's inflammatory and antiviral functions

6 Dec 2021

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

A novel mechanism by which SARS-CoV-2 inhibits the innate immune response; that is, ORF10 induces mitophagy-mediated MAVS degradation by binding to NIX.

5 Dec 2021

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

A new study supports the hypothesis that heterologous vaccination can provide an increased immune response against virus infection, supporting several other studies that have indicated similar events.

5 Dec 2021

New approach to COVID-19 immune profiling using blood-based machine learning

A new study discusses the application of a novel deconvolution model AImmune to predict moderate and severe cases of COVID-19.

5 Dec 2021

Systematic review: The involvement of bitter taste receptors in cancer

Humans have 25 different types of functional bitter taste receptors. These are found on our tongue, where they facilitate the taste perception of bitter tasting compounds. In addition, there are increasing findings that cells of extra-oral organs also have such receptors.

4 Dec 2021

Genes News and Research

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

Researchers discover biomarker that could aid in early detection of high risk COVID-19 patients

Scientists find new way to reverse aggressive breast cancer into a less dangerous kind

New research reveals how Europeans evolved greater resistance against anthrax

‘Moving molecule’ therapy for severe spinal cord injury

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

COVID-19 severity is correlated with T cell receptor repertoire signatures

Scientists find infection of sustentacular cells in the olfactory epithelium of COVID-19 patients

Announcing the Winners of The Scientist’s Top 10 Innovations of 2021

New therapeutic targets for the treatment and prevention of hypertension, cardiovascular diseases

Gene expression related to liver metabolism altered by spaceflight

Meth use and intimate partner violence drive exhaustion of immune cells in HIV patients

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

New approach to COVID-19 immune profiling using blood-based machine learning

Systematic review: The involvement of bitter taste receptors in cancer

New genetic technology for gene expression analysis of cancer cells

Penn researchers illuminate key molecular details of T-cell exhaustion process

Study sheds new light on how certain neurons regulate the number of heart muscle cells

Study documents and visualizes hearing loss-associated genes in the inner ear

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo