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Study compares effects of two types of sugar on metabolic and vascular function

The type of sugar you eat—and not just calorie count—may determine your risk for chronic disease.

20 Jan 2017

Study examines differences in liver damage between binge drinkers and heavy drinkers

Alcoholic liver disease (ALD) occurs on a spectrum of severity. The majority of people who drink excessively develop a fatty liver, which though often symptom free, can progress to a state of inflammation, fibrosis, and cell death that can be fatal.

20 Jan 2017

MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

Use of an advanced form of the commonly used polymerase chain reaction (PCR) method to analyze circulating tumor cells (CTCs) may greatly increase the ability to diagnose early-stage cancer, increasing the likelihood of successful treatment.

20 Jan 2017

UC biologists use frog models to study how early stressors may play role in onset of adult diseases

UC biologists have turned to amphibian sources -- specifically frogs and tadpoles -- to help shed light on how early stressors in the womb and shortly after birth may play a part in the onset of adult diseases such as diabetes and cardiovascular disease.

19 Jan 2017

Endogenous peptide inhibits atherosclerosis by reducing cholesterol levels

Cells of the innate immune system that play an important role in development of atherosclerosis contain a protein that reduces levels of cholesterol in mice - and thus helps to inhibit or mitigate the disease.

19 Jan 2017

Scientists identify 'molecular barcode' in blood samples that can predict survival of Ebola patients

Scientists have identified a 'molecular barcode' in the blood of patients with Ebola virus disease that can predict whether they are likely to survive or die from the viral infection.

19 Jan 2017

Researchers uncover new pathway in the body that stimulates liver repair

A team of Michigan State University researchers, led by James Luyendyk in the College of Veterinary Medicine, has uncovered a new pathway in the body that stimulates liver repair.

19 Jan 2017

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

UT Southwestern Medical Center researchers have uncovered the mechanism by which the stress hormone FGF21 keeps digestive enzymes from damaging the pancreas.

18 Jan 2017

BetterYou magnesium can raise cellular mineral levels faster than traditional tablets

Low magnesium levels are leading to a worrying level of undissolved calcium and increased heavy metal toxicity which can severely impact on our health and wellbeing, say mineral analysis experts.

From BetterYou Ltd 18 Jan 2017

New review discusses about care for pediatric liver transplant recipients

A new review discusses important consideration when caring for children who have received liver transplants.

18 Jan 2017

Study provides insights into CPEB4 gene and fatty liver disease

This condition generally leads to chronic inflammation (non-alcoholic steatohepatitis), which can trigger fibrosis, cirrhosis and ultimately liver cancer. This study on the basic biology of the liver paves the way to examine therapeutic strategies to fight and prevent fatty liver disease.

18 Jan 2017

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

Accurate test for jaundice could lead to effective treatment in premature newborns

Seeking to improve the care of preterm infants, a new study by researchers at Rutgers Robert Wood Johnson Medical School has found a more accurate test for jaundice, a common disorder in newborns.

17 Jan 2017

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

16 Jan 2017

Novel treatment can effectively inhibit development of GVHD in mice, study shows

Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants.

12 Jan 2017

Childhood obesity starts in the womb?

There is incontrovertible evidence that some harmful drugs and toxins can affect lifelong health. For example, if women take certain drugs in pregnancy, such as thalidomide, there are well documented effects on lifelong health. These have obvious and dramatic effects on the child...

11 Jan 2017

Antioxidant may prevent development of NAFLD in offspring of obese mothers

In new research published online in The FASEB Journal, scientists show that the antioxidant pyrroloquinoline quinone may prevent the development of nonalcoholic fatty liver disease in offspring.

10 Jan 2017

Epigenetic changes favor development of fatty liver in humans and mice

Mice with a strong tendency to obesity already exhibit epigenetic changes at six weeks of age, inducing the liver to amplify its production of the enzyme DPP4 and release it into the circulation. Over the long term, this favors the development of a fatty liver.

9 Jan 2017

New report reveals 25% drop in overall cancer death rate in the U.S.

A steady decline over more than two decades has resulted in a 25% drop in the overall cancer death rate in the United States. The drop equates to 2.1 million fewer cancer deaths between 1991 and 2014.

5 Jan 2017

Natural antioxidant can protect offspring of obese mice from NAFLD, study shows

A common antioxidant found in human breast milk and foods like kiwi fruit can protect against nonalcoholic fatty liver disease in the offspring of obese mice, according to researchers at the University of Colorado Anschutz Medical Campus.

4 Jan 2017

Liver News and Research

Study compares effects of two types of sugar on metabolic and vascular function

Study examines differences in liver damage between binge drinkers and heavy drinkers

MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

UC biologists use frog models to study how early stressors may play role in onset of adult diseases

Endogenous peptide inhibits atherosclerosis by reducing cholesterol levels

Scientists identify 'molecular barcode' in blood samples that can predict survival of Ebola patients

Researchers uncover new pathway in the body that stimulates liver repair

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

BetterYou magnesium can raise cellular mineral levels faster than traditional tablets

New review discusses about care for pediatric liver transplant recipients

Study provides insights into CPEB4 gene and fatty liver disease

Epigenetic changes drive successful metastases of pancreatic cancer cells

Accurate test for jaundice could lead to effective treatment in premature newborns

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Novel treatment can effectively inhibit development of GVHD in mice, study shows

Childhood obesity starts in the womb?

Antioxidant may prevent development of NAFLD in offspring of obese mothers

Epigenetic changes favor development of fatty liver in humans and mice

New report reveals 25% drop in overall cancer death rate in the U.S.

Natural antioxidant can protect offspring of obese mice from NAFLD, study shows

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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