Drug Delivery News and Research

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Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.

New approach to tame botulinum toxin for drug delivery

While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum -- the most potent toxins known.

8 Jan 2021

CytoDel successfully delivers neuronal antibody in animal models of botulism

CytoDel, Inc., a privately-held corporation, today announces the publication of preclinical data on the Company's lead product, Cyto-111, in the peer-reviewed journal, Science Translational Medicine. The complete text of the article titled, "Neuronal Delivery of Antibodies has Therapeutic Effects in Animal Models of Botulism," can be found here.

7 Jan 2021

Non-toxic versions of botulism toxins can deliver therapeutic antibodies to treat botulism

Taking advantage of the chemical properties of botulism toxins, two teams of researchers have fashioned non-toxic versions of these compounds that can deliver therapeutic antibodies to treat botulism, a potentially fatal disease with few approved treatments.

6 Jan 2021

Researchers receive £230,000 to develop world's first smart vaccine device

Researchers at Swansea University have received £230,000 to develop the world's first smart vaccine device that will both deliver the COVID-19 vaccine and measure its efficacy through monitoring the body's associated response.

6 Jan 2021

A paper-based sensor for detecting COVID-19

News-Medical talks to Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes.

5 Jan 2021

Researchers create new polymer to deliver DNA and RNA-based therapies for diseases

University of Minnesota Twin Cities researchers in the Department of Chemistry have created a new polymer to deliver DNA and RNA-based therapies for diseases.

21 Dec 2020

Low-intensity pulsed ultrasound combined with microbubbles might enhance chemotherapy delivery

Application of low-intensity pulsed ultrasound in combination with microbubbles might enhance the delivery of chemotherapy medication used for treating cancers.

17 Dec 2020

Researchers use new method to deliver anti-cancer drug to suppress tumor growth

Targeting drugs to cancer tissues is a major challenge in cancer treatment. Mesenchymal stem cells (MSCs) are known for their ability to find and target tumor cells in the body, but using MSCs for drug delivery has been tricky, because upon loading with drugs, MSCs lose their viability and migratory ability.

17 Dec 2020

Head injuries and long sleep deprivation can affect neurogenerative processes

Scientists from the School of Biomedicine of Far Eastern Federal University (FEFU) with colleagues from Italy, Spain, Romania, and Sweden suggest a way to protect the brain and minimize neurodegenerative processes after concussion head injuries in the presence of extensive previous sleep deprivation.

9 Dec 2020

Research shows how targeted microbubbles can carry powerful cancer drugs

New research has shown how microbubbles carrying powerful cancer drugs can be guided to the site of a tumor using antibodies.

8 Dec 2020

Penn study opens the door to let CAR T cells reach the tumor microenvironment

The labyrinth of jumbled blood vessels in the tumor microenvironment remains one of the toughest blockades for cellular therapies to penetrate and treat solid tumors.

30 Nov 2020

Study shows how high frequency sound waves could revolutionize ultrasound-driven chemistry

Researchers have revealed how high-frequency sound waves can be used to build new materials, make smart nanoparticles and even deliver drugs to the lungs for painless, needle-free vaccinations.

25 Nov 2020

Cerebrospinal fluid may play underappreciated role in both good health and response to injury

Swelling is one of the most dangerous and immediate consequences of a brain injury or stroke. Doctors have long known about the dangers of swelling, which has traditionally been blamed on ruptured blood vessels.

24 Nov 2020

Researchers conduct aerosol characterization experiments to protect healthcare workers from COVID-19

The rapid spread of COVID-19 overwhelmed hospitals that were unable to contend with the increasing number of patients, many requiring ventilators and other critical care. Such conditions can put medical workers at risk. Now researchers are studying methods to increase hospital safety and efficacy during the pandemic.

24 Nov 2020

KHN’s ‘What the Health?’: Transition troubles mount as COVID spreads

President-elect Joe Biden is still being blocked from launching his official transition while President Donald Trump contests the outcome of the election. That could be particularly dangerous for public health as COVID-19 spreads around the country at an alarming rate.

20 Nov 2020

Study demonstrates 24-hour rat liver viability in a normothermic machine perfusion system

In a paper published in TECHNOLOGY, a team of researchers from Massachusetts General Hospital (MGH) has demonstrated 24-hour rat liver viability in a normothermic machine perfusion (NMP) system.

18 Nov 2020

Novel protein imaging method could lead to the development of new biomaterials

Scientists have established a new method to image proteins that could lead to new discoveries in disease through biological tissue and cell analysis and the development of new biomaterials that can be used for the next generation of drug delivery systems and medical devices.

17 Nov 2020