Fracture News and Research

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Findings from UCB funded study suggests that osteoporosis is being under-treated

UCB today announced results from a comprehensive real world database analysis that assessed the rates of osteoporosis treatment initiation within one year following a first fracture in patients in Sweden. The data showed that only 6.6% of patients, who were treatment naive, were initiated on osteoporosis treatment. This analysis, performed by Quantify Research and funded by UCB, was presented today at the Annual European Congress of Rheumatology (EULAR) 2017 in Madrid, Spain.

14 Jun 2017

Researchers use 3D printing-inspired process to create new blood vessels in teeth

While root canals are effective in saving a tooth that has become infected or decayed, this age-old procedure may cause teeth to become brittle and susceptible to fracture over time. Now researchers at OHSU in Portland, Oregon, have developed a process by which they can engineer new blood vessels in teeth, creating better long-term outcomes for patients and clinicians.

12 Jun 2017

$Low BMI puts female runners at increased risk of developing stress fractures$

Low BMI puts female runners at increased risk of developing stress fractures

Carrying less weight may make female runners faster, but a new study from The Ohio State University Wexner Medical Center shows it may also put them at a higher risk for injuries.

12 Jun 2017

Researchers explore sea urchin protein to understand self-assembly of skeletal structures

Calcium carbonate, or CaCO3, comprises more than 4% of the earth's crust. Its most common natural forms are chalk, limestone, and marble, produced by the sedimentation of the shells of small fossilized snails, shellfish, and coral over millions of years.

8 Jun 2017

ACR’s updated guideline provides recommendations on treatment of glucocorticoid-induced osteoporosis

The American College of Rheumatology's updated clinical guideline for the prevention and treatment of glucocorticoid-induced osteoporosis is now available online.

7 Jun 2017

$Study finds higher risk of fractures among older, long-term bisphosphonate users$

Study finds higher risk of fractures among older, long-term bisphosphonate users

Osteoporosis is a disease that causes thinning of the bones, loss of bone density, and increasingly fragile bones. This puts people at higher risk for bone fractures. Risk for the disease increases as we age. In fact, 50% of women over the age of 50 will experience a bone facture due to osteoporosis.

2 Jun 2017

$CTs of core muscle may help identify optimal treatments for older patients with hip fractures$

CTs of core muscle may help identify optimal treatments for older patients with hip fractures

Using computed tomography (CT) to evaluate muscle health may help identify optimal treatments for older patients who fall and break their hips, a new study led by radiologists from UC Davis and Wake Forest Baptist medical centers has found.

2 Jun 2017

$Study finds link between type 1 diabetes and increased risk of bone fractures in men$

Study finds link between type 1 diabetes and increased risk of bone fractures in men

A Norwegian study has established that men with type 1 diabetes are more likely to suffer bone fractures because of lower bone density, poorer bone quality and a lower rate of bone growth.

23 May 2017

$Innovative technique could replace bone grafts to repair severe limb fractures$

Innovative technique could replace bone grafts to repair severe limb fractures

A Cedars-Sinai-led team of investigators has successfully repaired severe limb fractures in laboratory animals with an innovative technique that cues bone to regrow its own tissue.

17 May 2017

Untargeted vitamin D supplementation provides little clinical benefit to older adults, study finds

An international study of older adults has found that mass, untargeted provision of vitamin D supplements provides little clinical benefit to many when it comes to the common bone disease, osteoporosis. Instead, the study recommends targeting vitamin D supplements at individuals whose levels of this vitamin are markedly reduced.

16 May 2017

Yogurt intake may increase hip bone density, reduce risk of osteoporosis in older adults

The largest observational study to date of dairy intakes and bone and frailty measurements in older adults has found that increased yogurt consumption was associated with a higher hip bone density and a significantly reduced risk of osteoporosis in older women and men on the island of Ireland, after taking into account traditional risk factors.

10 May 2017

$New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds$

New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds

A team of researchers of the University of Barcelona and the Hospital del Mar Medical Research Institute have discovered a new mutation that has an impact on the bone so that it is vulnerable to the bisphosphonate, a drug used to treat osteoporosis.

4 May 2017

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

A newly released study published in the Journal of Immunity, Inflammation and Disease and conducted by the Sapienza University of Rome, Italy, found a multi-strain, high concentration, probiotic formulation that helped reconstitute the physical and immunological integrity of the gastrointestinal lining in HIV-1-positive patients on antiretroviral therapy.

3 May 2017

Study highlights risk factors for widespread vitamin D deficiency

Results from a clinical review published in The Journal of the American Osteopathic Association find nearly 1 billion people worldwide may have deficient or insufficient levels of vitamin D due to chronic disease and inadequate sun exposure related to sunscreen use.

2 May 2017

$Newly prescribed hypnotic medicines double the odds of hip fracture$

Newly prescribed hypnotic medicines double the odds of hip fracture

Older people newly prescribed sleeping pills like benzodiazepines and 'Z-drugs' have over double the odds of a hip fracture in the first two weeks compared with non-users, according to a new study by researchers at Cardiff University and King's College London.

26 Apr 2017

$Women at highest genetic risk for fracture benefit most from hormone therapy, study finds$

Women at highest genetic risk for fracture benefit most from hormone therapy, study finds

Women at the highest genetic risk for fracture benefit the most from hormone therapy, according to a first-of-its-kind study led by researchers at the University at Buffalo.

24 Apr 2017

Thyroid cancer patients with bone metastases have worse survival, study finds

When cancer metastases, bone unwittingly offers a friendly place for tumor cell growth--only to have its hospitality betrayed by pathologic fractures, spinal cord compression, the need for bone surgery or irradiation, and an increased risk of death.

17 Apr 2017

Common drugs, uncommon risks? Higher rate of serious problems after short-term steroid use

Millions of times a year, Americans get prescriptions for a week's worth of steroid pills, hoping to ease a backache or quell a nagging cough or allergy symptoms. But a new study suggests that they and their doctors might want to pay a bit more attention to the potential side effects of this medication.

14 Apr 2017

Amgen, UCB present romosozumab Phase 2 results at ENDO 2017

Amgen and UCB today announced results from the fourth year of a Phase 2 study showing the efficacy and safety of a second course of treatment with EVENITY™* (romosozumab), an investigational agent for postmenopausal women with osteoporosis.

3 Apr 2017

Researchers use mathematical modeling to raise density of bones badly degraded by osteoporosis

They may seem rigid and set in their ways, but your bones are actually under constant construction and deconstruction. They give up their nutrient treasures (calcium) to the body and then rebuild in a constant give-and-take sort of rhythm.

29 Mar 2017