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Olfactory tissue regeneration requires inflammatory processes that create loss of smell

In a mouse study designed to understand how chronic inflammation in sinusitis damages the sense of smell, scientists at Johns Hopkins say they were surprised to learn that the regeneration of olfactory tissue requires some of the same inflammatory processes and chemicals that create injury and loss of smell in the first place.

30 Aug 2017

UIC researchers identify enzyme that triggers corneal inflammation

One of the symptoms of herpes simplex virus-1 infection of the eye is lingering inflammation of the cornea – the clear outer layer of the eyeball.

11 Jul 2017

Quantum dots may someday provide relief for eye infections

Quantum dots are transforming electronic displays on TVs and tablets. But now, one group reports in ACS Nano that these tiny structures may someday provide relief for eye infections resulting from contact lens wear, trauma or some types of surgeries.

5 Jul 2017

Study opens the lid on overprescribing of antibiotics for acute conjunctivitis

A new study suggests that most people with acute conjunctivitis, or pinkeye, are getting the wrong treatment.

29 Jun 2017

New lab-on-a chip predicts preterm birth risk

Preterm birth is the leading cause of neonatal morbidity and mortality. Among the many underlying causes of pregnancy-associated complications, it is known that infection and inflammation are highly significant risk factors.

29 Jun 2017

Study finds link between upper GI infections and protein implicated in Parkinson’s disease

Acute and chronic infections in a person's upper gastrointestinal tract appear to be linked to Parkinson's disease, say scientists at Georgetown University Medical Center and their collaborators at the National Institutes of Health and other institutions.

28 Jun 2017

Drug cocktail may be effective in preventing progressive organ dysfunction, deaths from sepsis

Sepsis presents a major challenge for health care providers, especially in low-income countries where the mortality rate can exceed 60 percent.

27 Jun 2017

Most people with acute conjunctivitis get wrong treatment, study suggests

A new study suggests that most people with acute conjunctivitis, or pink eye, are getting the wrong treatment. About 60 percent of patients are prescribed antibiotic eyedrops, even though antibiotics are rarely necessary to treat this common eye infection.

19 Jun 2017

New guidelines for anti-rheumatic drug management in patients having joint replacement surgery

In the first such collaboration of its kind, an expert panel of rheumatologists and orthopedic surgeons has developed guidelines for the perioperative management of anti-rheumatic medication in patients undergoing total hip or knee replacement.

16 Jun 2017

New study finds lower levels of estrogen in women with stress urinary incontinence

Sex steroid levels change markedly during menopause, and estrogen deficiency after menopause causes changes within the urogenital tract.

7 Jun 2017

Trial shows promising results for new medicine in treating severe asthma patients

A trial led by a McMaster University respirology professor shows promising results for a new medicine for severe asthma patients.

25 May 2017

Body fat can help treat bone joint injuries and osteoarthritis

Body fat now can help treat bone joint conditions, including injuries and osteoarthritis – the type of arthritis caused by wear and tear in tissue between joints, which affects 27 million people.

19 May 2017

FDA-approved drug improves clinical outcomes among patients with rare immunologic disease

Adding the injectable drug mepolizumab to standard treatment for eosinophilic granulomatosis with polyangiitis (EGPA), a rare immunologic disease, significantly improved clinical outcomes among participants in an advanced clinical trial, scientists report.

18 May 2017

Exercising burns fat in bone marrow to improve bone health, study shows

It's a fat-burning secret anyone interested in bone health should know. For the first time, UNC School of Medicine researchers show that exercising burns the fat found within bone marrow and offers evidence that this process improves bone quality and the amount of bone in a matter of weeks.

18 May 2017

Weekly doses of steroids help hasten recovery in muscle injuries

Weekly doses of glucocorticoid steroids, such as prednisone, help speed recovery in muscle injuries, reports a new Northwestern Medicine study. The weekly steroids also repaired muscles damaged by muscular dystrophy.

17 May 2017

Discovery of steroid hormone in fruit flies may shed new light on maternal hypothyroidism

University of Oregon researchers using Drosophila have identified a steroid hormone that triggers a vital transition in early brain development in which neural stem cells properly change gears to produce different kinds of neurons.

15 May 2017

New findings pinpoint key feature of rare childhood disease that could help fast-track diagnosis

Australian scientists have shown, for the first time, that a family of untethered proteins builds up in the cells of children with a rare and serious genetic condition, known as mevalonate kinase deficiency (MKD).

10 May 2017

Study: Systemic therapy preserves vision of uveitis patients better than intraocular implant

Systemic therapy consisting of corticosteroids and immunosuppressants preserved vision of uveitis patients better - and had fewer adverse outcomes - than a long-lasting corticosteroid intraocular implant, according to a clinical trial funded by the National Eye Institute.

9 May 2017

Study finds effective treatment approach for preserving long-term vision in patients with severe uveitis

Researchers comparing leading treatment approaches for patients with severe uveitis have discovered that systemic therapy with oral corticosteroids and immunosuppression can preserve or improve vision in the long term better than regional implant therapy can.

8 May 2017

Steroids offer no additional relief to emergency patients suffering from hives

Despite standard use for the itching associated with urticaria (commonly known as hives), prednisone (a steroid) offered no additional relief to emergency patients suffering from hives than a placebo did, according to a randomized, placebo-controlled, double-blind, parallel-group study published online yesterday in Annals of Emergency Medicine.

4 May 2017