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Drug combination delivered by nanoparticles may keep melanoma from becoming resistant to treatment

The first of a new class of medication that delivers a combination of drugs by nanoparticle may keep melanoma from becoming resistant to treatment, according to Penn State College of Medicine researchers.

15 Mar 2017

ASPS statistics reveal new cosmetic trends in facelifts and fat

New data released by the American Society of Plastic Surgeons reveals that Americans want to put their best face and body forward as their annual plastic surgery procedural statistics show a three percent growth in cosmetic procedures over the last year.

1 Mar 2017

Scientists develop in vitro stem cell-based bioassay for detecting biological activity of BoNTs

Scientists at the Institute for Infectious Diseases, University of Bern have developed an in vitro stem cell-based bioassay grown on multi-electrode arrays capable of detecting the biological activity of Clostridium botulinum neurotoxins.

28 Feb 2017

MIT researchers develop new machine to rapidly produce customized peptides

Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections.

27 Feb 2017

Children born of fathers exposed to nicotine inherit enhanced chemical tolerance, study shows

A father's nicotine use may have a significant impact on children's risk of some diseases. In a study published in the online biomedical sciences journal eLife, Oliver J. Rando, MD, PhD, and colleagues at UMass Medical School, demonstrate that mice born of fathers who are habitually exposed to nicotine inherit enhanced chemical tolerance and drug clearance abilities.

14 Feb 2017

Plant-based drug for hemophilia shows promise in animal models

People with hemophilia require regular infusions of clotting factor to prevent them from experiencing uncontrolled bleeding. But a significant fraction develop antibodies against the clotting factor, essentially experiencing an allergic reaction to the very treatment that can prolong their lives.

13 Feb 2017

UNC scientists confirm and clarify key molecular details of nucleotide excision repair

Day in and day out, in our bodies, the DNA in cells is damaged for a variety of reasons, and thus intercellular DNA-repair systems are fundamental to the maintenance of life.

8 Feb 2017

Body dysmorphic disorder may be ‘under-diagnosed’ by cosmetic professionals, study suggests

Plastic surgeons and other cosmetic professionals are familiar with the challenges posed by patients with body dysmorphic disorder (BDD) seeking cosmetic procedures, reports a survey study in the February issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

7 Feb 2017

Sleep may be regulated by several brain-based immune proteins, study reveals

Sleep -- one of the most basic, yet most mystifying processes of the human body -- has confounded physicians, scientists and evolutionary biologists for centuries.

2 Feb 2017

NIH researchers shed light on role of S. epidermidis toxin in bacterial sepsis

Staphylococcus epidermidis bacteria are a significant health concern for hospitalized infants, children and anyone with implanted medical devices.

2 Feb 2017

New treatment for C.diff infections reduces recurrences by 40%, study finds

A new treatment for Clostridium difficile (C.diff) infections reduces recurrent infections by nearly 40%, a large study has found.

25 Jan 2017

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

UT Southwestern Medical Center researchers have uncovered the mechanism by which the stress hormone FGF21 keeps digestive enzymes from damaging the pancreas.

18 Jan 2017

Skidmore College scientist discovers health benefits of balanced, protein-pacing, low-calorie diet

Research by Skidmore College exercise scientist Paul Arciero has found that a balanced, protein-pacing, low-calorie diet that includes intermittent fasting not only achieves long-term weight loss, but also helps release toxins in the form of PCBs from the body fat stores, in addition to enhancing heart health and reducing oxidative stress.

12 Jan 2017

S. pneumoniae uses hosts' immune defenses to spread infection, study reveals

The bacteria that cause most cases of pneumonia worldwide secrete a toxin that helps them jump from one body to the next - with help from the hosts' immune defenses. This is the finding of a study led by researchers from NYU Langone Medical Center and published online January 11 in Cell Host & Microbe.

12 Jan 2017

Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Using a mouse model, scientists from the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology and a number of other institutes have identified a sugar molecule that reduced the inflammatory response and progress of emphysema, a common component of chronic obstructive pulmonary disease (COPD).

27 Dec 2016

Genomic sequencing reveals new insights into major shigellosis outbreaks in California

In a study that could have significant impact on how disease outbreaks are managed, researchers at UC Davis and the California Department of Public Health have sequenced and analyzed genomes from Shigella sonnei (S. sonnei) bacteria associated with major shigellosis outbreaks in California in 2014 and 2015.

23 Dec 2016

Overexpression of nerve growth factor drives gastric tumorigenesis in mice

Gastric tumors are started by specialized cells in the stomach that signal nerves to make more acetylcholine, according to a study in mice.

16 Dec 2016

Common bacterium that causes gum infections may trigger rheumatoid arthritis

Investigators at Johns Hopkins report they have new evidence that a bacterium known to cause chronic inflammatory gum infections also triggers the inflammatory "autoimmune" response characteristic of chronic, joint-destroying rheumatoid arthritis (RA).

15 Dec 2016

Researchers discover first toxin antitoxin system in biofilms

Bacterial resistance does not come just through adaptation to antibiotics, sometimes the bacteria simply go to sleep.

8 Dec 2016

Queen's University expert to lead new €4m initiative for assessing impact of chemicals on health

A Queen's University Belfast expert is leading a €4m international initiative to investigate whether natural toxins and manmade chemicals are creating potentially dangerous mixtures that affect our natural hormones and cause major illnesses such as cancer, obesity, diabetes or infertility.

7 Dec 2016