Genes News and Research

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Non-coding RNA plays a key role in regulating behavior of chromosome loops and gene expression

An important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes, according to a new study by researchers at Massachusetts General Hospital.

2 Dec 2021

Men with inherited gene mutation have high risk of aggressive prostate cancer

Men who inherit mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found.

2 Dec 2021

Study explores the emergence and spread of SARS-CoV-2 Delta variant across Brazil

Brazilian researchers aim to determine the emergence and spread of the Delta VOC in different regions in Brazil.

2 Dec 2021

Advancing our understanding of T cells to improve cancer therapies

In this interview, News-Medical talks to Dr. Brendan Horton about his latest research which has shed new light on cancer and T cells.

2 Dec 2021

Systematic survey of human SARS-CoV-2 monoclonal antibodies

Scientists have mined information from several research publications and patents to create a dataset of approximately 8000 human antibodies to the SARS-CoV-2 spike from more than 200 donors.

2 Dec 2021

Role of interferon type I-driven responses associated with disease control in COVID-19

New research suggests that treatment with type I interferons in the early stage of COVID-19 may supress disease progression by limiting SARS-CoV-2 in hosts.

1 Dec 2021

Scientists identify new genes associated with familial Meniere's disease

A team of scientists from the University of Granada (UGR) and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research—led by Pablo Roman-Naranjo and Jose Antonio López-Escámez, researcher in charge of the Biohealth Research Institute in Granada (ibs.GRANADA)—has identified new genes associated with familial Meniere's disease.

1 Dec 2021

Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

30 Nov 2021

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

Immunotherapies have shown striking clinical benefit in the treatment of many cancers, especially when used in combination with chemotherapy.

30 Nov 2021

Researchers genetically map cell types that make up the mouse iris

Johns Hopkins Medicine researchers report they have genetically mapped the cell types that make up the mouse iris — the thin disc of pigmented tissue that, in humans, gives eyes their distinct colors.

30 Nov 2021

'Biosensor barcodes' can identify and track how cancer cells 'talk' to each other

Ever since the first barcode appeared on a pack of chewing gum in 1974, the now-ubiquitous system has enabled manufacturers, retailers and consumers to quickly and effectively identify, characterize, locate and track products and materials.

30 Nov 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

New combination treatment enables complete tumor regression in mice with high-risk neuroblastoma

In mice with high-risk neuroblastoma, tumors disappeared in response to a new combination treatment with precision medicines, a recent study from University of Gothenburg researchers shows.

30 Nov 2021

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

In the largest genetic study of suicide attempts to date, researchers have identified a region of the genome on chromosome 7 containing DNA variations that increase the risk that a person will attempt suicide.

30 Nov 2021

Microbiome research opens up new perspectives for healthy and climate-resilient crops

Agriculture is facing enormous challenges worldwide due to global changes caused by human activities. Drought, severe weather events, record temperatures and emerging pathogens threaten the world's food supply.

30 Nov 2021

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

In a recent study, published on the bioRxiv* preprint server, researchers identified human LRRC15 as an inhibitory receptor for SARS-CoV-2 entry, which directly binds to the receptor-binding domain (RBD) of the spike protein with a moderate affinity and inhibits spike-mediated entry.

29 Nov 2021

New phenotype of LRP6 mutation reported for the first time in patients with tooth agenesis

A group led by Prof. Han Dong of Peking University School of Stomatology reported for the first time hand preaxial polydactyly in patients with tooth agenesis carrying a previously unknown mutation of low-density lipoprotein receptor-related protein 6 (LRP6).

29 Nov 2021

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that rare variants in the ANK2 gene, consistently found in individuals with autism spectrum disorder (ASD), can alter architecture and organization of neurons, potentially contributing to autism and neurodevelopmental comorbidities.

29 Nov 2021

Genes News and Research

Non-coding RNA plays a key role in regulating behavior of chromosome loops and gene expression

Men with inherited gene mutation have high risk of aggressive prostate cancer

Study explores the emergence and spread of SARS-CoV-2 Delta variant across Brazil

Advancing our understanding of T cells to improve cancer therapies

Systematic survey of human SARS-CoV-2 monoclonal antibodies

Role of interferon type I-driven responses associated with disease control in COVID-19

Scientists identify new genes associated with familial Meniere's disease

Novel anti-inflammatory drug target identified by CRISPR

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

Researchers genetically map cell types that make up the mouse iris

'Biosensor barcodes' can identify and track how cancer cells 'talk' to each other

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

New combination treatment enables complete tumor regression in mice with high-risk neuroblastoma

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

Microbiome research opens up new perspectives for healthy and climate-resilient crops

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

New phenotype of LRP6 mutation reported for the first time in patients with tooth agenesis

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

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