Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Stem cells with heart bypass surgery trial to begin

The University of Pittsburgh Medical Center (UPMC) has been granted approval by the U.S. Food and Drug Administration (FDA) to conduct a clinical trial to determine the safety and feasibility of injecting a patient's own bone marrow-derived stem cells directly into the heart during conventional heart bypass surgery.

25 Aug 2005

FDA Approves Aceon to reduce risk of cardiovascular mortality in patients with stable coronary artery disease

Solvay Pharmaceuticals and CV Therapeutics have announced that the U.S. Food and Drug Administration (FDA) has approved Aceon (perindopril erbumine) Tablets for the treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or non-fatal myocardial infarction (MI).

24 Aug 2005

MRI helps map smallest deformations inside hearts

Using magnetic resonance imaging technology, or MRI, to tag the work of millions of individual strands of heart muscle fibers, researchers at Johns Hopkins have successfully mapped the smallest deformations inside the beating hearts of 441 middle-aged and elderly men and women who have either silently developed heart disease or remained healthy.

22 Aug 2005

Enzyme in the blood that could be a potential marker for heart failure

A team of scientists led by Walter Koch, Ph.D., director of the Center for Translational Medicine in the Department of Medicine in Jefferson Medical College of Thomas Jefferson University in Philadelphia, previously showed that an enzyme called GRK2 or beta-adrenergic kinase (ßARK1) is critically important in heart function.

22 Aug 2005

New guidelines to battle heart failure

Early diagnosis and new treatments can help battle heart failure -- a growing national problem that causes 1 million hospital admissions each year, according to new guidelines released by the American College of Cardiology (ACC) and the American Heart Association (AHA).

22 Aug 2005

Low hemoglobin levels are a predictor of increased risk of death among heart failure patients

Hemoglobin (Hgb) is the major substance in red blood cells, and its level indicates the blood's ability to carry oxygen throughout the body. Studies have shown that low hemoglobin, which may result in anemia, is more common among patients with heart failure than it is among people in the general population.

17 Aug 2005

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.

16 Aug 2005

Mission to teach patients about modern treatments for sinusitis

Coughing, headaches, fatigue, post-nasal drip and intense pressure throughout the face. For millions of Americans, these aren't just the side effects of a short bout with the flu, but what they experience every day living with sinusitis.

16 Aug 2005

New study shows even non-prescription painkillers raise blood pressure in women

According to a new U.S. study women who take higher doses of common, over-the-counter painkillers, such as Ibuprofen and even Tylenol, have higher blood pressure than women who do not.

16 Aug 2005

Chronic use of nitroglycerin for chest pain could lead to mitochondrial damage

Definitive evidence to explain how the drug nitroglycerin relieves chest pain has resulted from a new study by Howard Hughes Medical Institute investigators at Duke University Medical Center. Nitroglycerin relaxes blood vessels to boost blood flow, yet the mechanism by which the drug works has remained a matter of scientific controversy.

16 Aug 2005

Men and women receive remarkably similar outpatient care at the Department of Veterans Affairs (VA),

The study looked at nine measures of quality care that are equally appropriate for women and men, including pneumonia and influenza vaccinations; colorectal cancer screenings; and eye examinations for diabetics, to determine what percentage of VA patients received appropriate care for their gender.

11 Aug 2005

Current clinical practice guidelines are not written with older adults with multiple illnesses in mind

The aging of the population and the increasing prevalence of chronic diseases pose challenges to the development and application of clinical practice guidelines (CPGs), according to background information in the article. In 1999, 48 percent of Medicare beneficiaries aged 65 years or older had at least 3 chronic medical conditions and 21 percent had 5 or more.

10 Aug 2005

New theory as to why some people die during sleep

According to scientists the reason why some people stop breathing fatally in their sleep, is because a cumulative loss of cells in the area of the brain that controls breathing triggers a condition called central sleep apnoea.

9 Aug 2005

Nighttime dying linked to sleep apnea from brain cell loss

Aim to grow old and die peacefully in your sleep? Be careful what you wish for. A new UCLA study suggests that some people die in their sleep because they stop breathing due to a cumulative loss of cells in the brain's breathing command-post. The online edition of Nature Neuroscience reports the findings.

7 Aug 2005

FDA approval for Diovan (Valsartan)

Novartis Pharmaceuticals Corporation announced today that the US Food and Drug Administration (FDA) approved Diovan (valsartan), the most prescribed ARB (angiotensin receptor blocker) in the US and worldwide, for a new indication to reduce cardiovascular death in patients at high risk (with left ventricular failure or left ventricular dysfunction) following a heart attack.

4 Aug 2005

Guidant receives FDA approval to re-enter heart failure market

Guidant Corporation has announced U.S. Food and Drug Administration (FDA) approval to re-launch its CONTAK RENEWAL 3 family of cardiac resynchronization therapy (CRT) defibrillators in the United States.

2 Aug 2005

Possible early warning system for heart problems

By using sound waves Mayo Clinic researchers have described subtle changes in the motion of the heart that are measurable by ultrasound and may improve understanding of heart function, and possibly be a noninvasive aid in predicting impending heart damage including heart attacks.

31 Jul 2005

Controlling high blood pressure in individuals age 80 years and older has become a major national health problem

The study found that almost three fourths of those 80 years and older have hypertension -- blood pressure greater than 140 systolic over greater than 90 diastolic. Fewer than 10 percent have "normal" blood pressure levels -- less than 120 systolic over less than 80 diastolic.

26 Jul 2005

Guidant prepared to launch heart failure devices outside the United States

Guidant Corporation has received Conformité Européenne (CE) Mark approval to launch its CONTAK RENEWAL 4 cardiac resynchronization therapy defibrillators for use outside the United States.

26 Jul 2005

Eplerenone shows benefit for patients with damaged hearts

In the first thirty days following a heart attack, one in three deaths among patients with signs of heart failure may be preventable by early treatment with a drug called eplerenone (Inspra, Pfizer Ltd), according to new data published in the Journal of the American College of Cardiology (JACC).

26 Jul 2005