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Next generation sequencing in malignant pleural mesothelioma tumors reveals complex mutational setting

Next generation sequencing in malignant pleural mesothelioma (MPM) tumors shows a complex mutational setting with a high number of genetic alterations in genes involved in DNA repair, cell survival and cell proliferation pathways. Increased accumulation of mutations correlates with early progression of the tumor and decreased survival.

23 Dec 2014

Mirati begins dosage in MGCD265 Phase 1b clinical trial for NSCLC

Mirati Therapeutics, Inc. today announced that the first patient with Non-Small Cell Lung Cancer (NSCLC) has been dosed in a Phase 1b clinical trial of MGCD265 in selected patients exhibiting genetic alterations of MET or Axl.

23 Dec 2014

Multicenter, clinical trial to address long-term complications in CKD patients

in collaboration with Parkland Health and Hospital System, Texas Health Resources, VA North Texas Health Care System, and ProHealth Physicians, Inc. of Connecticut - will lead the first National Institutes of Health-funded, multicenter, clinical trial to address interventions for patients with multiple chronic conditions centered around kidney disease.

23 Dec 2014

Higher doses of vancomycin linked to increased risk of kidney damage in children, shows study

Results of a small Johns Hopkins Children’s Center study show that hospitalized children given high-dose IV infusions of the antibiotic vancomycin to treat drug-resistant bacterial infections face an increased risk for kidney damage — an often reversible but sometimes serious complication.

23 Dec 2014

Researchers identify new genetic anomalies in smoking-related lung cancers

Developing effective treatments for lung cancer has been challenging, in part because so many genetic mutations play a role in the disease.

22 Dec 2014

Ganciclovir drug resistance may occur more frequently in cystic fibrosis patients

A drug called ganciclovir is given to lung transplant patients to protect against a life-threatening virus that is common after transplantation.

22 Dec 2014

UT Southwestern researchers find new potential target for halting tumor growth

UT Southwestern Medical Center researchers have discovered that brain tumors are capable of burning acetate for fuel, providing a new potential target for halting tumor growth.

19 Dec 2014

Gene variations predispose mestizo Mexican population to develop severe form of COPD

A study by Ramcés Falfán-Valencia, researcher at the National Institute of Respiratory Diseases, found that the mestizo Mexican population has a number of variations in certain genes that predispose them to develop the most severe form of chronic obstructive pulmonary disease (COPD).

19 Dec 2014

Single biopsy site may reveal all lung adenocarcinoma genetic mutations

Genetic sequencing of a single tumour site sample may be adequate for identifying cancer gene mutations in patients with lung andenocarcinoma, research published in Science suggests.

18 Dec 2014

CF patients require close monitoring for resistance to ganciclovir after lung transplantation

A drug called ganciclovir is given to lung transplant patients to protect against a life-threatening virus that is common after transplantation.

18 Dec 2014

U-M researchers devise reliable way to grow tumor cells

In a development that could lead to a deeper understanding of cancer and better early-stage treatment of the disease, University of Michigan researchers have devised a reliable way to grow a certain type of cancer cells from patients outside the body for study.

18 Dec 2014

Elekta's Flexitron brachytherapy afterloading platform approved in China

Elekta announces that the China Food and Drug Administration has approved Elekta's Flexitron brachytherapy afterloading platform for sale and marketing in China.

From Elekta 18 Dec 2014

UAH forms new Learning and Technology Resource Center to train student nurses

The University of Alabama in Huntsville College of Nursing has formed a new Learning and Technology Resource Center (LTRC) to consolidate its use of technology and lifelike patient simulators to train students and to further research in healthcare simulation education.

18 Dec 2014

Inovio begins hTERT DNA immunotherapy trial in adults with breast, lung and pancreatic cancer

Inovio Pharmaceuticals, Inc. announced it has initiated a phase I trial of its hTERT DNA immunotherapy (INO-1400) alone or in combination with Inovio's IL-12 immune activator (INO-9012) in adults with breast, lung, or pancreatic cancer at high risk of relapse after surgery and other cancer treatments.

18 Dec 2014

Survey highlights need for increased public education on benefits of lung cancer screening in France

A prospective nationwide survey on perceptions of lung cancer in the general population of France highlights a need for increased public education on the benefits of lung cancer screening, the good survival rates of early-stage disease and the improved outcomes with new therapeutic strategies, including targeted-therapies.

18 Dec 2014

University Hospital Bonn to validate accuracy of VolitionRx’s Nucleosomics technology in lung cancer

VolitionRx Limited, a life sciences company focused on developing diagnostic tests for cancer and other conditions, today announced that the University Hospital Bonn in Germany will initiate a clinical confirmatory study to assess VolitionRx’s proprietary Nucleosomics platform technology for the diagnosis of lung cancer through a blood test in individuals.

18 Dec 2014

More open discussions needed when referring patients for cancer investigation, study says

GPs should consider a more overt discussion with patients when referring them for further investigation of symptoms which may indicate cancer, according to a paper published in the British Journal of General Practice.

18 Dec 2014

Diabetes drug can boost efficacy of TB medication without causing drug resistance

A more effective treatment for tuberculosis (TB) could soon be available as scientists have discovered that Metformin (MET), a drug for treating diabetes, can also be used to boost the efficacy of TB medication without inducing drug resistance.

17 Dec 2014

Researchers find new 'sliding scale' model to rule out blood clots in lungs

Researchers from Intermountain Medical Center in Salt Lake City have identified a new "sliding scale" model used to rule out potentially deadly blood clots in the lungs, known as pulmonary embolisms, that is more accurate than current diagnostic methods.

17 Dec 2014

Postop chemotherapy supported for stage III NSCLC

Study findings challenge the belief that preoperative chemotherapy is superior to postoperative chemotherapy for patients with clinical stage III non-small-cell lung cancer.

17 Dec 2014

Lungs News and Research

Next generation sequencing in malignant pleural mesothelioma tumors reveals complex mutational setting

Mirati begins dosage in MGCD265 Phase 1b clinical trial for NSCLC

Multicenter, clinical trial to address long-term complications in CKD patients

Higher doses of vancomycin linked to increased risk of kidney damage in children, shows study

Researchers identify new genetic anomalies in smoking-related lung cancers

Ganciclovir drug resistance may occur more frequently in cystic fibrosis patients

UT Southwestern researchers find new potential target for halting tumor growth

Gene variations predispose mestizo Mexican population to develop severe form of COPD

Single biopsy site may reveal all lung adenocarcinoma genetic mutations

CF patients require close monitoring for resistance to ganciclovir after lung transplantation

U-M researchers devise reliable way to grow tumor cells

Elekta's Flexitron brachytherapy afterloading platform approved in China

UAH forms new Learning and Technology Resource Center to train student nurses

Inovio begins hTERT DNA immunotherapy trial in adults with breast, lung and pancreatic cancer

Survey highlights need for increased public education on benefits of lung cancer screening in France

University Hospital Bonn to validate accuracy of VolitionRx’s Nucleosomics technology in lung cancer

More open discussions needed when referring patients for cancer investigation, study says

Diabetes drug can boost efficacy of TB medication without causing drug resistance

Researchers find new 'sliding scale' model to rule out blood clots in lungs

Postop chemotherapy supported for stage III NSCLC

The ultimate guide to lung research tools and protocols eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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