Protein C News and Research

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Urine-diverting toilets can reduce a person’s exposure to virus particles

Parents often give their children useful advice: Wash your hands, cover your cough and put the toilet lid down before flushing.

6 Feb 2023

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Researchers determine the association between diet, microbe-derived metabolites, and cytokine levels with anxiety and depression among obese adults.

6 Feb 2023

Study examines clinical risk factors for kidney function decline in children with CKD

Chronic kidney disease (CKD) in children is rare, which makes it difficult to study and leaves major gaps in the quantity and quality of evidence that informs the care of pediatric patients with the condition.

6 Feb 2023

Cryo-EM provides new insights into the structure of the centromeric region

The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle microtubules when cells divide and grow.

6 Feb 2023

New method for ultra-fast detection of coronavirus using nanosensors

The ability of gold particles to reflect light in different colors is used in applications from stained glass to pregnancy tests.

6 Feb 2023

Changes in the cerebral neural network could function as a biomarker for neurocognitive disorders

In many neurodegenerative conditions, brain changes occur before symptoms emerge. But now, researchers from Japan have found a new way to distinguish these conditions in the early stages according to changes in brain activity patterns.

6 Feb 2023

Recent therapeutic strategies for renal cell carcinoma and the effects of the tumor microenvironment on systemic therapy

Researchers explored the association between the human microbiome and improved renal cell carcinoma outcomes.

6 Feb 2023

New type of immunotherapy effective in mice with ovarian cancer

CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ImmunoTherapy of Cancer.

6 Feb 2023

Researchers discover how a protein deficiency can prepare the brain to minimize damage after stress

Astrocytes, small star-shaped cells, play an important role in signal transmission in the brain. Since the protein Ezrin is found abundantly in astrocyte tendrils, it is presumed to play a role in brain function.

3 Feb 2023

Penn scientists discover a cellular pathway that keeps Ebola virus from exiting human cells

In their evolutionary battle for survival, viruses have developed strategies to spark and perpetuate infection. Once inside a host cell, the Ebola virus, for example, hijacks molecular pathways to replicate itself and eventually make its way back out of the cell into the bloodstream, where it can spread further.

3 Feb 2023

Experimental vaccine completely protects cynomolgus macaques against lethal Sudan virus

A National Institutes of Health research group with extensive experience studying ebolavirus countermeasures has successfully developed a vaccine against Sudan virus (SUDV) based on the licensed Ebola virus (EBOV) vaccine.

3 Feb 2023

UT Southwestern research could lead to new ways of controlling gene regulation

UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery.

3 Feb 2023

Targeting a single enzyme can kill prostate cancer cells

For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme, called PI5P4Kα.

3 Feb 2023

Study identifies a drug candidate for the treatment of fatty liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases.

3 Feb 2023

The effectiveness of intranasal COVID-19 vaccination in healthy adults

A recent study discusses the safety profiles and immunogenicity of the nasal BBV154 COVID-19 vaccine in healthy adults.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein.

3 Feb 2023

Researchers discover a new hexameric structure of the RepB protein and how it binds to DNA

In all living organisms, DNA replication is essential to ensure the genetic fidelity of the next generation. However, bacteria can also transfer genetic information horizontally to other bacteria.

3 Feb 2023

Are plasma levels of axonal damage and neuronal degeneration makers altered in COVID-19 patients without major neurological manifestations?

A recent study evaluated whether plasma levels of NfL, T-tau, and GFAP changed in SARS-CoV-2-infected patients with or without major neurological manifestations.

3 Feb 2023

The human body develops strategies to prevent the immune response from overshooting its mark

The signaling molecules of the immune system should trigger a response only where necessary. To prevent a life-threatening spread to the rest of the body, connective tissue can absorb these molecules like a sponge.

3 Feb 2023

Protein C News and Research

Urine-diverting toilets can reduce a person’s exposure to virus particles

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Study examines clinical risk factors for kidney function decline in children with CKD

Cryo-EM provides new insights into the structure of the centromeric region

New method for ultra-fast detection of coronavirus using nanosensors

Changes in the cerebral neural network could function as a biomarker for neurocognitive disorders

Recent therapeutic strategies for renal cell carcinoma and the effects of the tumor microenvironment on systemic therapy

New type of immunotherapy effective in mice with ovarian cancer

Researchers discover how a protein deficiency can prepare the brain to minimize damage after stress

Penn scientists discover a cellular pathway that keeps Ebola virus from exiting human cells

Experimental vaccine completely protects cynomolgus macaques against lethal Sudan virus

UT Southwestern research could lead to new ways of controlling gene regulation

Targeting a single enzyme can kill prostate cancer cells

Study identifies a drug candidate for the treatment of fatty liver disease

The effectiveness of intranasal COVID-19 vaccination in healthy adults

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Researchers discover a new hexameric structure of the RepB protein and how it binds to DNA

Are plasma levels of axonal damage and neuronal degeneration makers altered in COVID-19 patients without major neurological manifestations?

The human body develops strategies to prevent the immune response from overshooting its mark

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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