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Three alternative diabetes markers found

Experts have identified three alternative biomarkers that may be useful for picking up on diabetes risk.

13 Aug 2012

Playing away stops bugs being kept at bay

Elite athletes who travel to compete in countries with a time zone difference of over 5 hours are more than twice as likely to fall ill as are athletes who remain in their home country, write researchers in the British Journal of Sports Medicine.

13 Aug 2012

Novel Cornelia de Lange syndrome gene discovered

Scientists have discovered that mutations in the histone deacetylase 8 gene can cause the rare genetic disorder known as Cornelia de Lange syndrome, which is characterized by intellectual disability, limb deformity, and other disabilities resulting from problems in early development.

13 Aug 2012

High-cost imaging increasingly used for stage IV cancer patients

High-cost diagnostic imaging was increasingly used for elderly patients with stage IV cancer of the breast, lung, and prostate, and colorectal cancer in the USA, research demonstrates.

13 Aug 2012

Tofacitinib efficacy suggested for rheumatoid arthritis

The novel oral Janus kinase inhibitor tofacitinib significantly reduces signs and symptoms of rheumatoid arthritis, report two phase III trials published in TheNew England Journal of Medicine.

13 Aug 2012

Quintiles acquires premier provider of genomics testing and analysis

To help biopharmaceutical companies dramatically improve drug development productivity and deliver greater value, Quintiles today announced the acquisition of Expression Analysis, Inc. (EA), a premier provider of genomics testing and analysis to biopharma, academic, government and non-profit customers.

13 Aug 2012

Researchers identify new gene in Cornelia deLange syndrome

Genetics researchers have identified a key gene that, when mutated, causes the rare multisystem disorder Cornelia deLange syndrome (CdLS). By revealing how mutations in the HDAC8 gene disrupt the biology of proteins that control both gene expression and cell division, the research sheds light on this disease, which causes intellectual disability, limb deformations and other disabilities resulting from impairments in early development.

13 Aug 2012

Twelve states currently have adult obesity rate above 30%

Twelve states currently have an adult obesity rate above 30 percent, according to a new analysis released today by the Trust for America's Health (TFAH) and the Robert Wood Johnson Foundation (RWJF).

13 Aug 2012

Researchers discover gene mutations linked to spinocerebellar ataxia

A global hunt for the cause of a crippling inherited nerve disorder has found its target. The discovery opens the door for better diagnosis and treatment of this particular disease - but also for better understanding of why nerves in the brain's movement-controlling center die, and how new DNA-mapping techniques can find the causes of other diseases that run in families.

13 Aug 2012

NYU Langone offers chance to participate in lung cancer early detection study

NYU Langone Medical Center is a pioneer in lung cancer screening and offers comprehensive screening for individuals at risk for lung cancer. The NYU Langone Lung Cancer Screening Center is distinguished by its multidisciplinary approach and wealth of experience and is under the direction of the Divisions of Pulmonary Medicine, Thoracic Radiology and Thoracic Surgery.

13 Aug 2012

Latrepirdine demonstrates new potential against neurodegenerative conditions

The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative conditions. An international team led by Mount Sinai School of Medicine scientists found that latrepiridine, known commercially as Dimebon, reduced the level of at least two neurodegeneration-related proteins in mice.

13 Aug 2012

Epigenetic factors involved in treatment-resistance to schizophrenia drugs

Researchers at Mount Sinai School of Medicine may have discovered why certain drugs to treat schizophrenia are ineffective in some patients. Published online in Nature Neuroscience, the research will pave the way for a new class of drugs to help treat this devastating mental illness, which impacts one percent of the world's population, 30 percent of whom do not respond to currently available treatments.

13 Aug 2012

Popular class of diabetes drugs increase risk for bladder cancer

A popular class of diabetes drugs increases patients' risk of bladder cancer, according to a new study published online this month in the Journal of the National Cancer Institute.

13 Aug 2012

Biosense Webster launches new CARTO 3 Multi-Electrode Mapping Version

Biosense Webster, Inc., a worldwide leader in the diagnosis and treatment of cardiac arrhythmias, announced the launch of the new CARTO 3 MEM (Multi-Electrode Mapping) Version in the United States.

13 Aug 2012

UTSW reports successful delivery of quintuplets

Three boys and two girls were born Thursday, Aug. 9, to missionaries Carrie and Gavin Jones at UT Southwestern Medical Center, among the first sets of quintuplets delivered nationally so far this year.

13 Aug 2012

Medical ethics: an interview with Anita Silvers

Medical ethics assists healthcare professionals to make decisions respectful of persons who happen to be their patients.

13 Aug 2012

Leukoaraiosis modifies brain function in the elderly

Researchers at the Mayo Clinic say a common condition called leukoaraiosis, made up of tiny areas in the brain that have been deprived of oxygen and appear as bright white dots on MRI scans, is not a harmless part of the aging process, but rather a disease that alters brain function in the elderly.

13 Aug 2012

HDAC8 gene mutations cause Cornelia deLange syndrome

13 Aug 2012

Johns Hopkins CIDR receives NIH contract to study genetic diseases

The Johns Hopkins Center for Inherited Disease Research (CIDR) program contract, which provides up to $101 million in research funding from the National Institutes of Health (NIH) to study the genetic contribution to human diseases, has been renewed for another five years.

13 Aug 2012

Scientists discover why major depression or chronic stress can cause loss of brain mass

Major depression or chronic stress can cause the loss of brain volume, a condition that contributes to both emotional and cognitive impairment. Now a team of researchers led by Yale scientists has discovered one reason why this occurs - a single genetic switch that triggers loss of brain connections in humans and depression in animal models.

13 Aug 2012