Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New insights into how miR-30d can promote healthy insulin production

Work by Michigan Technological University biologist Xiaoqing Tang is yielding new insights into how a tiny snippet of genetic material can promote healthy insulin production in mice.

13 Oct 2012

Perception test could predict mild cognitive impairment

Psychologists at the University of Toronto and the Georgia Institute of Technology - commonly known as Georgia Tech - have shown that an individual's inability to recognize once-familiar faces and objects may have as much to do with difficulty perceiving their distinct features as it does with the capacity to recall from memory.

12 Oct 2012

Investigators provide overview of role of dopamine in modulating the immune system

Dopamine is a neurotransmitter that is associated with emotions, movement, and the brain's pleasure and reward system. In the current issue of Advances in Neuroimmune Biology, investigators provide a broad overview of the direct and indirect role of dopamine in modulating the immune system and discuss how recent research has opened up new possibilities for treating diseases such as Parkinson's and Alzheimer's disease, schizophrenia, multiple sclerosis or even the autoimmune disorders.

11 Oct 2012

Amarantus acquires option to license LymPro Alzheimer's diagnostic blood test from MDx

Amarantus BioSciences, Inc., a biotechnology company developing new treatments and diagnostics for Parkinson's disease and Traumatic Brain Injury centred on its proprietary anti-apoptotis therapeutic protein MANF, today announced that it has acquired an exclusive option to license the LymPro Alzheimer's Diagnostic Blood Test from Memory Dx, LLC (MDx), formerly known as Provista Life Sciences, LLC.

11 Oct 2012

Researchers create mouse model that reproduces brain chemical changes associated with AD

Researchers at Western University have created a mouse model that reproduces some of the chemical changes in the brain that occur with Alzheimer's, shedding new light on this devastating disease.

11 Oct 2012

Stroke on the rise among young people

New research reveals that stroke may be affecting people at a younger age. The study is published in the October 10, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

11 Oct 2012

Leading scientists select first drugs to be evaluated in Alzheimer's clinical study

Leading scientists have selected the first drugs to be evaluated in a worldwide clinical study to determine whether they can prevent Alzheimer's disease.

11 Oct 2012

New drug candidate improves cognitive function of rats with Alzheimer's-like mental impairment

Washington State University researchers have developed a new drug candidate that dramatically improves the cognitive function of rats with Alzheimer's-like mental impairment.

11 Oct 2012

Researchers identify astrocytes as new target for Alzheimer's

Alzheimer's disease is a severe neurodegenerative disease that affects 45% of people over 85 years of age. The research teams of Prof. Jin-Moo Lee at Washington University in Saint Louis, USA, and Prof. Milos Pekny at Sahlgrenska Academy in Gothenburg, Sweden, have identified astrocytes as a novel target for the development of future treatment strategies. The results have just been published in the FASEB Journal.

10 Oct 2012

Study compares gene expression levels in two key hippocampal regions affected by Alzheimer's

Researchers from the Computational Intelligence Group based at the Universidad Politécnica de Madrid's Facultad de Informática have used machine learning and data mining techniques to compare gene expresssion levels in Alzheimer's disease (AD) patients in two key regions of the hippocampus: the dentate gyrus, where the disease appears to have little or no effect, and the entorhinal cortex, where Alzheimer's disease produces major neuronal damage.

10 Oct 2012

Grp94 chaperone protein can interfere with clearance of myocilin from cells

The chaperone protein Grp94 can interfere with the clearance of another protein known to cause the glaucoma when mutated, a new study led by researchers at the University of South Florida has found. Using a cell model, the researchers also demonstrated that a new specific inhibitor of Grp94 facilitates clearance of the genetically-defective protein, called myocilin, from cells.

10 Oct 2012

RMND1 gene mutations responsible for severe neurodegenerative disorders

Scientists at the Montreal Neurological Institute and Hospital - The Neuro, McGill University working with a team at Oxford University have uncovered the genetic defect underlying a group of rare genetic disorders.

10 Oct 2012

Lilly announces detailed results from solanezumab Phase 3 trials on Alzheimer's

Eli Lilly and Company today announced its detailed results for the Phase 3, double-blind, placebo-controlled EXPEDITION studies in patients with mild-to-moderate Alzheimer's disease.

9 Oct 2012

Navigating the Labyrinth of Traumatic Brain Injury to Discover a Secondary Neurological Condition

Working with individuals with traumatic brain injury (TBI) every day, I see the debilitating effects and long-term struggles firsthand.

9 Oct 2012

Eating tomatoes associated with reduced risk of stroke

Eating tomatoes and tomato-based foods is associated with a lower risk of stroke, according to new research published in the October 9, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology. Tomatoes are high in the antioxidant lycopene.

9 Oct 2012

Scientists discover how protein deficiency may be linked to frontotemporal dementia

Using animal models, scientists at the Gladstone Institutes have discovered how a protein deficiency may be linked to frontotemporal dementia (FTD)-a form of early-onset dementia that is similar to Alzheimer's disease. These results lay the foundation for therapies that one day may benefit those who suffer from this and related diseases that wreak havoc on the brain.

9 Oct 2012

Alzheimer's disease diagnosis within minutes using a simple brain scan

Groundbreaking research taking place at the University of York could lead to Alzheimer's disease being diagnosed in minutes using a simple brain scan.

8 Oct 2012

Study provides direct evidence for persistent activity in medial entorhinal cortex layer neurons

UCLA researchers have for the first time measured the activity of a brain region known to be involved in learning, memory and Alzheimer's disease during sleep. They discovered that this part of the brain behaves as if it's remembering something, even under anesthesia, a finding that counters conventional theories about memory consolidation during sleep.

8 Oct 2012

Rember revamped for Phase 3 testing in behavioral-variant frontotemporal dementia

Rember—the blue dye that created a stir in 2008 when Phase 2 clinical trial data claimed that it slowed decline in people with Alzheimer's disease—has now been revamped for Phase 3 testing in another disease, behavioral-variant frontotemporal dementia (bvFTD).

6 Oct 2012

Researchers from three trials join to collaborate under European Dementia Prevention Initiative

Worldwide, the number of people with Alzheimer's disease will hit 115 million by 2050, according to the World Health Organization. Scientists, health officials, policymakers, and the public are asking if anything can slow down the disease.

6 Oct 2012

Alzheimer's Disease News and Research

Further Reading

New insights into how miR-30d can promote healthy insulin production

Perception test could predict mild cognitive impairment

Investigators provide overview of role of dopamine in modulating the immune system

Amarantus acquires option to license LymPro Alzheimer's diagnostic blood test from MDx

Researchers create mouse model that reproduces brain chemical changes associated with AD

Stroke on the rise among young people

Leading scientists select first drugs to be evaluated in Alzheimer's clinical study

New drug candidate improves cognitive function of rats with Alzheimer's-like mental impairment

Researchers identify astrocytes as new target for Alzheimer's

Study compares gene expression levels in two key hippocampal regions affected by Alzheimer's

Grp94 chaperone protein can interfere with clearance of myocilin from cells

RMND1 gene mutations responsible for severe neurodegenerative disorders

Lilly announces detailed results from solanezumab Phase 3 trials on Alzheimer's

Navigating the Labyrinth of Traumatic Brain Injury to Discover a Secondary Neurological Condition

Eating tomatoes associated with reduced risk of stroke

Scientists discover how protein deficiency may be linked to frontotemporal dementia

Alzheimer's disease diagnosis within minutes using a simple brain scan

Study provides direct evidence for persistent activity in medial entorhinal cortex layer neurons

Rember revamped for Phase 3 testing in behavioral-variant frontotemporal dementia

Researchers from three trials join to collaborate under European Dementia Prevention Initiative

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