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Mechanism provides beneficial characteristics of energy-burning brown fat to white fat

Columbia University Medical Center (CUMC) researchers have identified a mechanism that can give energy-storing white fat some of the beneficial characteristics of energy-burning brown fat. The findings, based on studies of mice and of human fat tissue, could lead to new strategies for treating obesity and type 2 diabetes.

3 Aug 2012

Missouri Supreme Court strikes down cap on medical malpractice damages

Missouri's Supreme Court has ruled that a 20-year-old, $350,000 cap on noneconomic medical malpractice damages -- pain and suffering -- takes away a citizen's right to trial by jury and is unconstitutional.

3 Aug 2012

Experts offer disparate views on controlling health care costs

Dueling articles in the New England Journal of Medicine Wednesday propose sharply different ways to curb medical spending. The proposals offer a glimpse of the rival approaches that could emerge in 2013, when Congress will have to tackle the budget deficit and the future of the Medicare program for the elderly and disabled.

3 Aug 2012

Sta Op Tegen Kanker International Translational Cancer Research Grant recipients announced

Stand Up To Cancer (SU2C) and the Dutch Cancer Society (KWF Kankerbestrijding), along with the American Association for Cancer Research (AACR), SU2C's Scientific Partner, announce the recipients of the Sta Op Tegen Kanker International Translational Cancer Research Grant.

3 Aug 2012

Longer looks: Mississippi learns from Iran's health care system

Sabrina Seeling seemed too young to die. ... One night she stayed up all night translating a Latin text into English for a college paper. ... During the all-nighter, Ms. Seelig took Ephedra, a stimulant diet drug that had been banned by the Food and Drug Administration three years earlier, and had a few beers. ... When she felt sick, she called Poison Control for help, and spoke very clearly, a recording of the call shows.

3 Aug 2012

Depression in kidney cancer patients associated with survival and inflammatory gene regulation

Research from The University of Texas MD Anderson Cancer Center has found that symptoms of depression in patients with newly diagnosed metastatic kidney cancer are associated with survival and inflammatory gene regulation may explain this link.

3 Aug 2012

Survey results of adoption and implementation of therapeutic hypothermia in hospitals

National guidelines recommend the use of therapeutic hypothermia to improve outcomes in patients who suffer a heart attack outside of a hospital. The results of a survey of all 73 acute care hospitals in New Jersey evaluating the adoption and implementation of this life-saving treatment from 2004-2011 is published in Therapeutic Hypothermia and Temperature Management, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

3 Aug 2012

First Edition: August 3, 2012

Today's headlines include reports on a Capitol Hill hearing during which House GOP lawmakers grilled the director of the Internal Revenue Service on his agency's health care subsidy ruling.

3 Aug 2012

Exercise benefits influenced by sRAGE levels in diabetes

Increased levels of the soluble form of the receptor for advanced glycation end products may underly the beneficial effects of exercise in patients with Type 2 diabetes, research shows.

3 Aug 2012

Potential PD biomarkers identified for sleep behavior disorder

Concomitant olfaction abnormality and increased substantia nigra echogenicity may be preclinical manifestations of parkinsonism in patients with idiopathic rapid eye movement sleep behavior disorder, research suggests.

3 Aug 2012

‘Fifth link’ improves outcomes after out-of-hospital cardiac arrest

Neurologic outcomes for survivors of out-of-hospital cardiac arrest are significantly improved after implementation of the 2010 American Heart Association's fifth link in the chain-of-survival concept for postresuscitation care, show Japanese study results.

3 Aug 2012

Mylan licenses rights to produce and market generic versions of Gilead HIV/AIDS therapies

Mylan Inc. today announced the establishment of a new agreement between its subsidiary Mylan Laboratories Limited and Gilead Sciences Inc. Under this agreement, Mylan has licensed the rights to produce and market generic versions of Gilead HIV/AIDS therapies containing Emtricitabine, including single and fixed-dose combinations.

3 Aug 2012

Mammography oversold by breast cancer charity

The world’s largest breast cancer charity comes under fire from experts today for using misleading statistics to persuade women to undergo mammography.

3 Aug 2012

Researchers identify how telomerase is recruited to chromosome ends

Stem cells are special. Nestled in muscle and skin, organ and bone, they bide their time over years or decades until called to replace damaged or lost tissue. One secret to their longevity is an enzyme called telomerase, which stills the relentless ticking of the molecular clock that limits the life span of other cells.

3 Aug 2012

Researchers discover surprising and unexpected plasticity in the embryonic endothelium

UCLA stem cell researchers have found for the first time a surprising and unexpected plasticity in the embryonic endothelium, the place where blood stem cells are made in early development.

3 Aug 2012

Researchers uncover 9 new genes associated with bone health

Researchers have uncovered 9 new genes associated with bone health. This collaborative study found clues to the cause of bone disorders such as osteoporosis, osteogenesis imperfecta, and high bone density syndromes by investigating the bone mineral content, strength and flexibility.

3 Aug 2012

Affymetrix announces availability of SensationPlus FFPE Amplification and 3' IVT Labeling Kit

Affymetrix, Inc. announced today the availability of SensationPlus FFPE Amplification and 3' IVT Labeling Kit (SensationPlus FFPE Reagent Kit), consisting of RNA amplification and labeling modules, to enable gene expression profiling of formalin-fixed, paraffin-embedded (FFPE) samples on GeneChip 3' IVT arrays and Almac XcelTM Array for disease clinical research and retrospective studies.

3 Aug 2012

SAGE Labs, Autism Speaks expand partnership to create first rat models for translational research

Autism Speaks, the world's leading autism science and advocacy organization, today announced its expanded collaboration with Sigma Advanced Genetic Engineering (SAGE) Labs, an initiative of Sigma- Life, to develop the first rat models with modified autism associated genes, intended to accelerate discovery and translational autism research.

3 Aug 2012

Anacardic acid can rescue some ALS phenotypes in vitro

A research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has successfully recapitulated amyotrophic lateral sclerosis (ALS)-associated abnormalities in motor neurons differentiated from induced pluripotent stem cells (iPSCs) obtained from patients with familial ALS, a late-onset, fatal disorder which is also known for Lou Gehrig's disease. In a drug screening assay using the disease model, the team further found that the chemical compound anacardic acid can rescue some ALS phenotypes in vitro.

3 Aug 2012

Fatty acid synthase provides new target for treatment of obesity and diabetes

Researchers at Washington University School of Medicine in St. Louis have identified a potential target for treating diabetes and obesity.

3 Aug 2012

Medicine News and Research

Mechanism provides beneficial characteristics of energy-burning brown fat to white fat

Missouri Supreme Court strikes down cap on medical malpractice damages

Experts offer disparate views on controlling health care costs

Sta Op Tegen Kanker International Translational Cancer Research Grant recipients announced

Longer looks: Mississippi learns from Iran's health care system

Depression in kidney cancer patients associated with survival and inflammatory gene regulation

Survey results of adoption and implementation of therapeutic hypothermia in hospitals

First Edition: August 3, 2012

Exercise benefits influenced by sRAGE levels in diabetes

Potential PD biomarkers identified for sleep behavior disorder

‘Fifth link’ improves outcomes after out-of-hospital cardiac arrest

Mylan licenses rights to produce and market generic versions of Gilead HIV/AIDS therapies

Mammography oversold by breast cancer charity

Researchers identify how telomerase is recruited to chromosome ends

Researchers discover surprising and unexpected plasticity in the embryonic endothelium

Researchers uncover 9 new genes associated with bone health

Affymetrix announces availability of SensationPlus FFPE Amplification and 3' IVT Labeling Kit

SAGE Labs, Autism Speaks expand partnership to create first rat models for translational research

Anacardic acid can rescue some ALS phenotypes in vitro

Fatty acid synthase provides new target for treatment of obesity and diabetes

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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