Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Ology Bioservices wins $8.4 million worth agreement to manufacture anti-Ebola monoclonal antibody

Ology Bioservices, Inc., a biologics contract development and manufacturing organization, announced today that it was awarded an Other Transaction Agreement to support the Joint Project Manager Medical Countermeasure Systems, a component of the Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense for advanced biologics manufacturing services—specifically, to manufacture an anti-Ebola monoclonal antibody.

17 Aug 2018

New project to combat DMD-related fibrosis receives major funding boost

Duchenne muscular dystrophy is one of the most common congenital diseases in the world, affecting one in 3,500 Canadian males. DMD is caused by mutations in the dystrophin gene that results in progressive muscle degeneration and there are currently no effective treatments for DMD.

17 Aug 2018

New technique detects, measures, analyzes unevenly charged biomolecules

In clinical diagnostics, it is critical to monitor biomolecules in a simple, rapid and sensitive way. Clinicians most often monitor antibodies because these small proteins attach to antigens, or foreign substances, we face every day.

17 Aug 2018

New HIV therapy suppresses viral replication and increases immune cells in drug-resistant patients

In a study, a new HIV drug reduced viral replication and increased immune cells in individuals with advanced, drug-resistant HIV infection. Used in combination with existing HIV medications, the drug is a promising strategy for patients who have run out of effective treatment options, the researchers said.

16 Aug 2018

New polyclonal immunotherapy successfully neutralizes Ebola virus

SAB Biotherapeutics, Inc., a clinical-stage biopharmaceutical company, today announced that its anti-Ebola immunotherapy (SAB-139) provided "100% protection against a lethal dose of the Ebola virus" in a recent animal study published in The Journal of Infectious Diseases.

15 Aug 2018

New model of genetically engineered immune cells may help fight solid tumors

Scientists at Memorial Sloan Kettering Cancer Center announced that they have built a new model of genetically engineered immune cells in mice that may allow them to fight solid tumors.

15 Aug 2018

Scripps Research scientists uncover new approach for treating thrombocytopenia

Blood platelets are like the sand bags of the body. Got a cut? Platelets pile in to clog the hole and stop the bleeding.

15 Aug 2018

Ebola outbreak in Congo spreads to active combat zone

The outbreak of the deadly Ebola in the Democratic Republic of Congo has spread outside the province of North Kivu according to a statement made by the country’s health ministry yesterday. With this the viral infection has reached an active conflict zone and this may mean that it could spread wider now.

14 Aug 2018

Study: IgG3 antibody stops B cells from fighting pathogens in HIV patients

For the first time, scientists have shown that in certain people living with HIV, a type of antibody called immunoglobulin G3 stops the immune system's B cells from doing their normal job of fighting pathogens.

14 Aug 2018

One-two punch of powerful antibodies may be best way to stop Ebola virus

A one-two punch of powerful antibodies may be the best way to stop Ebola virus, reports an international team of scientists in the journal Cell.

10 Aug 2018

Researchers describe new class of potent inhibitors against amyloid plaques

Effective therapeutics to counteract the formation of amyloid plaques in Alzheimer's disease and type 2 diabetes are not yet available.

9 Aug 2018

Researchers find faster way to analyze outcome of experimental vaccines

A team at Scripps Research has come up with a faster way to analyze the outcome of experimental vaccines against HIV and other pathogens.

9 Aug 2018

Researchers study whether chemotherapy could be encased in milk particles

You can't eat chemotherapy. That's because your digestive system breaks down the molecules you eat into smaller pieces that can be absorbed through the gut into the bloodstream.

9 Aug 2018

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

The U.S. Food and Drug Administration today approved Poteligeo (mogamulizumab-kpkc) injection for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides or Sézary syndrome after at least one prior systemic therapy.

8 Aug 2018

New CAR T-cell immunotherapy trial targets solid tumors

Seattle Children's has opened a chimeric antigen receptor (CAR) T-cell immunotherapy trial for children and young adults with relapsed or refractory non-central nervous system EGFR-expressing solid tumors. In the phase 1 trial, STRIvE-01, cancer-fighting CAR T cells will target the EGFR protein expressed in many childhood sarcoma, kidney and neuroblastoma tumors.

7 Aug 2018

New study finds key factors behind differences in immune responses

Age, sex, and specific human genetic variants are the key factors behind differences between immune responses among healthy humans, finds a study of 1,000 individuals carried out by EPFL and the Pasteur Institute.

6 Aug 2018

Mice study shows mother's dengue immunity protects unborn from ZIKA infection

Dengue and Zika viruses are closely related and carried by mosquitos. In infested subtropical and tropical areas, dengue transmission often precedes Zika virus infection, suggesting that women who previously acquired dengue immunity may be bitten by ZIKV-carrying mosquitoes during pregnancy.

2 Aug 2018

Researchers characterize production process for standardized monoclonal antibody

Researchers have taken the first step towards developing a method for the production of a standardized monoclonal antibody (mAb).

1 Aug 2018

Researchers engineer three cell lines to produce nonproprietary versions of NISTmAb

When the National Institute of Standards and Technology issued the world's first standardized monoclonal antibody in July 2016, the exhaustively analyzed protein known as NISTmAb was intended as a valuable tool for biopharmaceutical companies.

1 Aug 2018

European Commission approves Pfizer’s first oncology biosimilar

Pfizer Inc. today announced the European Commission has approved TRAZIMERA, a biosimilar to Herceptin (trastuzumab), for the treatment of human epidermal growth factor overexpressing breast cancer and HER2 overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.

31 Jul 2018