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Discovery of 11 new gene sites that influence cholesterol or triglyceride levels

An international research team has identified 11 novel locations in the human genome where common variations appear to influence cholesterol or triglyceride levels, bringing the total number of lipid-associated genes to 30.

8 Dec 2008

Studies examine quality of care for hospitalized sickle cell disease patients

A study assessing the quality of care for patients with sickle cell disease in a variety of hospital settings was presented Saturday, December 6 during the 50th Annual Meeting of the American Society of Hematology in San Francisco, CA.

8 Dec 2008

Hematopoietic stem cells found to reproduce more slowly than expected

Investigators from Massachusetts General Hospital (MGH) have found a subpopulation of hematopoietic stem cells, the source of all blood and immune system cells, that reproduce much more slowly than previously anticipated.

8 Dec 2008

Age has no impact on survival after bone marrow transplant

Age alone should not determine whether an older patient with acute myeloid leukemia or myelodysplastic syndrome receives a blood stem cell transplant from a matched donor, researchers of the Center for International Blood and Marrow Transplant Research reported today at the 50th annual meeting of the American Society of Hematology.

8 Dec 2008

New research reports on interventions that may alter the course of epilepsy diagnosis and management

Early diagnosis and treatment that quickly achieves seizure freedom with nominal side effects is the key goal to epilepsy management.

8 Dec 2008

Scientists find 12 new genes with potential as drug targets

Scientists have identified 12 new genes that are somewhat strange bedfellows: Some link gallstones and blood cholesterol levels, others link melatonin and sleep patterns to small increases in glucose levels and larger jumps in the risk of diabetes.

8 Dec 2008

MedImmune starts phase 2 trial of antibody targeting IL-5 receptor

MedImmune has announced that it has initiated a Phase 2 clinical trial in patients with chronic asthma to determine the safety of subcutaneous dosing of a humanized monoclonal antibody (MAb) that targets the interleukin-5 receptor (IL-5R).

8 Dec 2008

Kiadis Pharma announces positive results for ATIR in mismatched bone marrow transplantation

Biopharmaceutical company Kiadis Pharma announces that it has successfully completed treatment of the last patient on its ATIR phase I/II clinical trial.

8 Dec 2008

Dismissed leukemia drug flavopiridol helps chronic lymphocytic leukemia patients

A drug once dismissed as ineffective in patients with chronic lymphocytic leukemia (CLL) has shown promising results in two phase I and II clinical trials, according to researchers at The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.

8 Dec 2008

Biomarkers in blood could aid diagnosis of two severe and debilitating forms of malaria

Canadian researchers have identified protein biomarkers that shed new light on the development of two severe and debilitating forms of malaria.

8 Dec 2008

Allos Therapeutics announces results from phase 2 trial of Pralatrexate in peripheral T-cell lymphoma

Allos Therapeutics, Inc. has announced preliminary top line results from PROPEL, the Company's pivotal Phase 2 trial of pralatrexate (PDX) in patients with relapsed or refractory peripheral T-cell lymphoma (PTCL), at the 50th Annual Meeting of the American Society of Hematology (abstract 261).

8 Dec 2008

Calls for all pregnant women to be screened for Down syndrome

Experts say Australia needs a national screening policy for Down syndrome as research shows it could halve the number of babies born with the genetic condition.

8 Dec 2008

Daiichi Sankyo starts trial of investigational factor Xa inhibitor for atrial fibrillation

Daiichi Sankyo Company, Limited, has announced that it has initiated its pivotal Phase III trial for DU-176b, an investigational oral Factor Xa inhibitor, in patients with atrial fibrillation. DU-176b is being developed solely by Daiichi Sankyo.

7 Dec 2008

Sage tests high-tech solution for nursing shortage

One of the reasons for the shortage of nurses that continues to plague the heath care industry is too few clinical spaces where students can practice nursing care, but that's about to change with the increased use of high-tech mannequins that simulate real patient conditions including childbirth, trauma and many other real-world nursing situations.

5 Dec 2008