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Researchers discover reason why breast cancer cells become drug resistant

Breast cancer treatments such as Herceptin that target a marker called HER2 have dramatically improved outcomes for women with this type of cancer. But nearly half of these cancers are resistant to Herceptin from the start and almost all of them will eventually become resistant.

21 Jul 2012

New WHO guidance recommends use of ARVs for HIV prevention

WHO has issued its first guidance to countries that are considering offering HIV medications, known as antiretrovirals (ARVs), to protect people who do not have the virus but who are at high risk of HIV infection.

21 Jul 2012

Marshall University faculty member receives $426,000 NIH grant for lung cancer study

A Marshall University faculty member has been awarded a three-year, $426,000 grant by the National Institutes of Health (NIH) to further her lung cancer research.

21 Jul 2012

Viewpoints: Creating an HIV-free generation; Postal Service's struggle over retiree health benefits

HIV forces us to deal with so much: sex, drugs, poverty, racism, homelessness, homophobia, sexism, illness and death. While our nation's response has been imperfect, we have gotten a lot right. And we are now at a pivotal moment where science has led us to imagine the possibility of an HIV-free generation.

21 Jul 2012

FDA grants accelerated approval to Onyx's Kyprolis for treatment of multiple myeloma

Onyx Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval of Kyprolis (carfilzomib) for Injection, a proteasome inhibitor, indicated for the treatment of patients with multiple myeloma who have received at least two prior therapies, including bortezomib and an immunomodulatory agent, and have demonstrated disease progression on or within 60 days of completion of the last therapy.

21 Jul 2012

uniQure receives positive recommendation from EMA CHMP for Glybera

uniQure announced today that the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion that recommends marketing authorization of Glybera (alipogene tiparvovec) as a treatment for lipoprotein lipase deficiency (LPLD) under exceptional circumstances.

21 Jul 2012

Vitamin D might modify damaging effects of smoking on lung function

Vitamin D deficiency is associated with worse lung function and more rapid decline in lung function over time in smokers, suggesting that vitamin D may have a protective effect against the effects of smoking on lung function, according to a new study from researchers in Boston.

21 Jul 2012

Study identifies genetic markers that influence sex hormone-binding globulin

A research study led by Boston University School of Medicine (BUSM) and the University of Exeter in the United Kingdom, in collaboration with a global consortium, has identified genetic markers that influence a protein involved in regulating estrogen and testosterone levels in the bloodstream.

21 Jul 2012

Study opens way for new approaches to slow development of AIDS in HIV-1-infected patients

A new study from Lund University in Sweden has opened the way for new approaches to slowing the development of AIDS in HIV-1-infected patients. It is hoped that this could lead to better treatment methods and preventive measures to combat HIV and AIDS.

20 Jul 2012

Placenta-derived endothelial colony-forming cells are more vasculogenic: Study

A study comparing whether endothelial colony-forming cells (ECFCs) derived from human placenta or those derived from human umbilical cord blood are more proliferative and better for forming new blood vessels has found that ECFCs derived from human placenta are more vasculogenic.

20 Jul 2012

Montefiore physician to develop tablet computer app for children with cochlear implants

Elena Willis, MD Resident Physician, Department of Otorhinolaryngology - Head and Neck Surgery, Montefiore Medical Center, has been awarded a $10,000 Resident Research Grant by The American Academy of Otolaryngology - Head and Neck Surgery, sponsored by The Oticon Foundation, to develop a tablet computer app to help improve the speech of children with cochlear implants.

20 Jul 2012

Funding must support optimism surrounding HIV prevention, treatment

The goal of an "AIDS-free generation" "requires an ambitious implementation-science agenda that improves efficiency and effectiveness and incorporates strategies for overcoming the stigma and discrimination that continue to limit the uptake and utilization of treatment, prevention and care services," AIDS 2012 Co-Chair Diane Havlir of the University of California-San Francisco School of Medicine and Chris Beyrer of the Johns Hopkins Center for AIDS Research write in a New England Journal of Medicine opinion piece.

20 Jul 2012

CPAP benefits extend to mild OSA patients

The use of continuous positive airway pressure treatment, an effective option for severe obstructive sleep apnea, should be extended to sleepy patients with milder OSA, say US researchers.

20 Jul 2012

Breast-conserving surgery carries high reoperation risk

Women who undergo breast-conserving surgery for breast cancer may be at an increased risk for reoperation, research suggests.

20 Jul 2012

Low serum albumin associated with higher risk of graft failure in pediatric kidney transplants

For children receiving kidney transplants, a potentially correctable blood condition present in about one in four recipients is associated with a moderately increased risk of the graft's later failure, suggesting that clinicians should weigh whether transplant is advisable when the condition is present, according to UC Davis research presented today at the 24th International Congress of the Transplantation Society in Berlin.

20 Jul 2012

Silymarin does not offer significant improvements for patients with HCV

Silymarin, an extract of milk thistle commonly used to treat chronic liver disease by millions of people around the World, does not offer significant improvements for patients, according to a new study conducted by a nationwide group of researchers including faculty at the Perelman School of Medicine at the University of Pennsylvania.

20 Jul 2012

Scientists develop simple assay to diagnose 'superparasites'

Belgian scientists of the Institute of Tropical Medicine (ITM) in Antwerp, Belgium made a breakthrough in bridging high tech molecular biology research on microbial pathogens and the needs of the poorest of the poor. After sequencing the complete genome of Leishmania donovani (a parasite causing one of the most important tropical diseases after malaria) in hundreds of clinical isolates, they identified a series of mutations specific of 'superparasites' and developed a simple assay that should allow tracking them anywhere.

20 Jul 2012

Treating complex spinal pathologies: an interview with Eric Major

In the approximate $8 billion global spine market, the most specialized and demanding $1 billion complex spine segment includes deformity, trauma, and tumor pathologies.

20 Jul 2012

Short-term infection with intestinal worms may provide long-term protection against TID

Short-term infection with intestinal worms may provide long-term protection against type I diabetes (TID), suggests a study conducted by William Gause, PhD, and colleagues at the University of Medicine and Dentistry of New Jersey-New Jersey Medical School.

20 Jul 2012

Studies report on therapeutic efficacy of stem cell transplantation in animal models of ALS, SCI

Two studies published in a recent issue of Cell Medicine report on the therapeutic efficacy of stem cell transplantation in animal models of amyotrophic lateral sclerosis (ALS) and spinal cord injury (SCI).

20 Jul 2012

Medicine News and Research

Researchers discover reason why breast cancer cells become drug resistant

New WHO guidance recommends use of ARVs for HIV prevention

Marshall University faculty member receives $426,000 NIH grant for lung cancer study

Viewpoints: Creating an HIV-free generation; Postal Service's struggle over retiree health benefits

FDA grants accelerated approval to Onyx's Kyprolis for treatment of multiple myeloma

uniQure receives positive recommendation from EMA CHMP for Glybera

Vitamin D might modify damaging effects of smoking on lung function

Study identifies genetic markers that influence sex hormone-binding globulin

Study opens way for new approaches to slow development of AIDS in HIV-1-infected patients

Placenta-derived endothelial colony-forming cells are more vasculogenic: Study

Montefiore physician to develop tablet computer app for children with cochlear implants

Funding must support optimism surrounding HIV prevention, treatment

CPAP benefits extend to mild OSA patients

Breast-conserving surgery carries high reoperation risk

Low serum albumin associated with higher risk of graft failure in pediatric kidney transplants

Silymarin does not offer significant improvements for patients with HCV

Scientists develop simple assay to diagnose 'superparasites'

Treating complex spinal pathologies: an interview with Eric Major

Short-term infection with intestinal worms may provide long-term protection against TID

Studies report on therapeutic efficacy of stem cell transplantation in animal models of ALS, SCI

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