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Study finds higher risk of mortality among women than men after heart attack

Women are more than twice as likely to die after a heart attack than men, according to research presented today at Heart Failure 2023, a scientific congress of the European Society of Cardiology.

22 May 2023

Targeting mucus plugs could help prevent deaths from COPD, study suggests

A retrospective analysis of patient data from the COPDGene study suggests that targeting mucus plugs could help prevent deaths from chronic obstructive pulmonary disease - the fourth leading cause of death in the United States.

22 May 2023

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

In this interview, we spoke to Adrian Krainer, a Professor at Cold Spring Harbor Laboratory, about his latest research into the role of RNA splicing in one of the deadliest forms of pancreatic cancer.

22 May 2023

Amyloid-removing drug shows promise for the treatment of stiff-heart syndrome

Transthyretin-related cardiac amyloidosis is a progressive disease characterized by the deposition of amyloid protein fibrils in the heart. Amyloid fibril deposition thickens and stiffens the heart walls, and the disease is also known as stiff-heart syndrome.

22 May 2023

Toddler’s gut bacteria highly predictive of body mass index at age 5

The make-up and volume of gut bacteria in toddlers at 3.5 years old is predictive of body mass index (BMI) at age 5, irrespective of whether they are born prematurely or not, according to new research, being presented at this year's European Congress on Obesity (ECO) in Dublin, Ireland (17-20 May).

22 May 2023

Genetic insights unveil promising therapeutic targets for critical COVID-19

Critical COVID-19 illness reveals genetic associations with immunomodulatory therapies, as identified in a comprehensive analysis of 24,202 cases. This study uncovers novel genome-wide significant associations, highlighting potential druggable targets for inflammatory signaling, immunometabolism, and viral replication, offering insights into therapeutic implications.

21 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Unraveling the origins of humanity: New research challenges single-origin theory

Researchers explore the complex demographic history of Homo sapiens in Africa, revealing a reticulated population structure dating back to Marine Isotope Stage 5. The study challenges previous assumptions about archaic hominin contributions and emphasizes the significance of employing diverse models for robust inferences about ancient human history.

21 May 2023

MGH researchers identify a potential method for treating fragile X syndrome

New research has identified a potential method for treating fragile X syndrome, a leading cause of autism spectrum disorders that is characterized by an inherited repeat of certain nucleotides within the DNA sequence of the FMR1 gene.

19 May 2023

Genomes of modern humans shaped by admixture events

The course of human history has been marked by complex patterns of migration, isolation, and admixture, the latter a term that refers to gene flow between individuals from different populations.

19 May 2023

Researchers discover sex-specific genes, molecular pathways that contribute to Alzheimer's disease progression

Alzheimer's Disease (AD) is a complex neurodegenerative illness with genetic and environmental origins.

19 May 2023

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

19 May 2023

Study reports a shared genetic basis for cannabis use and psychiatric disorders

A new study from the University of Oslo published in the Lancet Psychiatry, reported a shared genetic basis for cannabis use and psychiatric disorders, including schizophrenia and bipolar disorder.

19 May 2023

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

19 May 2023

What are the genetic associations between modifiable risk factors and Alzheimer's disease?

Researchers assessed associations between genetic risk factors and Alzheimer's.

19 May 2023

Study hints at potential risk between unhealthy low-fat diets and postmenopausal breast cancer

Research explores the relationship between low-fat dietary patterns and breast cancer risk, emphasizing the significance of overall dietary choices beyond individual foods or nutrients. The study highlights the role of macronutrient source quality in influencing health outcomes.

19 May 2023

Going nuts for heart health: Mixed nuts consumption shows promising effects on cardiovascular risk factors

Researchers investigated the effect of daily consumption of mixed nuts on cardiovascular disease biomarkers in overweight and obese adults.

18 May 2023

MSU researchers create the first annotated Montmorency tart cherry genome

Since Michigan is the nation's leading producer of tart cherries, Michigan State University researchers were searching for the genes associated with tart cherry trees that bloom later in the season to meet the needs of a changing climate.

18 May 2023

Researchers uncover a new model of human evolution

In testing the genetic material of current populations in Africa and comparing against existing fossil evidence of early Homo sapiens populations there, researchers have uncovered a new model of human evolution - overturning previous beliefs that a single African population gave rise to all humans.

18 May 2023

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

The gene ECHS1 encodes for enoyl-CoA hydratase short-chain 1, a mitochondrial enzyme involved in branched-chain amino acid and fatty acid metabolism.

18 May 2023

Genetic News and Research

Study finds higher risk of mortality among women than men after heart attack

Targeting mucus plugs could help prevent deaths from COPD, study suggests

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

Amyloid-removing drug shows promise for the treatment of stiff-heart syndrome

Toddler’s gut bacteria highly predictive of body mass index at age 5

Genetic insights unveil promising therapeutic targets for critical COVID-19

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Unraveling the origins of humanity: New research challenges single-origin theory

MGH researchers identify a potential method for treating fragile X syndrome

Genomes of modern humans shaped by admixture events

Researchers discover sex-specific genes, molecular pathways that contribute to Alzheimer's disease progression

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Study reports a shared genetic basis for cannabis use and psychiatric disorders

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

What are the genetic associations between modifiable risk factors and Alzheimer's disease?

Study hints at potential risk between unhealthy low-fat diets and postmenopausal breast cancer

Going nuts for heart health: Mixed nuts consumption shows promising effects on cardiovascular risk factors

MSU researchers create the first annotated Montmorency tart cherry genome

Researchers uncover a new model of human evolution

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

Event guide: 2nd World RNA-Based Therapeutics & Vaccines Summit Korea eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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