Genetic News and Research

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Obesity driven by genetic factors linked to lower risk of cardiovascular disease

The risk of developing cardiovascular disease is lower in people with obesity who have a genetic predisposition for high BMI than people with obesity influenced mainly by environmental factors such as lifestyle, researchers from Karolinska Institutet report in eClinical Medicine.

6 Apr 2023

Study examines the causal role of insomnia symptoms on 11,409 health related-symptoms

Researchers performed Mendelian randomization phenome-wide association study of insomnia symptoms using 11,409 outcome variables.

6 Apr 2023

Using brain organoids to test gene therapies for a rare disease in children

Brain tissue grown in a laboratory by University of Queensland researchers will be used to test a treatment for a rare disease in children and help unlock therapies for a range of neurological disorders.

5 Apr 2023

IU study sheds new light on the development and treatment of rare form of muscular dystrophy

A study by Indiana University School of Medicine researchers sheds new light on the development and treatment of a rare form of muscular dystrophy.

5 Apr 2023

Understanding how surface factors influence or inhibit biofilm formation in the presence of antibiotics

Similar to how cells within human tissues communicate and function together as a whole, bacteria are also able to communicate with each other through chemical signals, a behavior known as quorum signaling (QS).

5 Apr 2023

Promising new combination of drugs identified to treat juvenile myelomonocytic leukemia

Indiana University School of Medicine researchers have identified a promising new combination of drugs to treat juvenile myelomonocytic leukemia (JMML), a rare form of blood cancer that affects children.

5 Apr 2023

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

The scientific foundation needed to work on curing a class of cancer-causing mutations is here, in the form of a tool from St. Jude Children's Research Hospital.

5 Apr 2023

IU researchers focus on tackling binge and "high-intensity" drinking

A multi-disciplinary team of Indiana University researchers is focusing their efforts on a growing public health concern: binge and "high-intensity" drinking - extreme drinking behaviors that are increasingly prevalent among college-age adults.

5 Apr 2023

New method for lower respiratory tract infection diagnosis in critically ill children

Lower respiratory tract infection (LRTI), which includes conditions such as pneumonia, has long been the leading cause of death from communicable agents and a leading cause of death in children worldwide.

5 Apr 2023

Scientists secure funding for cutting-edge research on age-related macular degeneration

A team of scientists led by a Northumbria University academic has won funding to research an eye disease suffered by over 190 million people worldwide.

5 Apr 2023

Biological underpinnings of a reproductive disorder caused by mutation of autism gene

A University of California, Riverside, study has identified the biological underpinnings of a reproductive disorder caused by the mutation of a gene.

5 Apr 2023

Antioxidant supplementation shows potential to improve male fertility

A new study discusses the benefits of antioxidant supplementation on male fertility.

4 Apr 2023

The interaction between white adipose tissue mitochondria and gut microbiota in obesity

Researchers explored the interaction of white adipose tissue mitochondria with gut microbiota in obesity.

4 Apr 2023

CRISPR screens reveal genetic determinants of PARP inhibition in prostate cancer

Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive.

4 Apr 2023

Healthy sleep pattern may help offset asthma risk regardless of genetic susceptibility

Poor quality sleep may bolster a person's genetic susceptibility to asthma, potentially doubling their risk of being diagnosed with the condition, suggests a large UK Biobank study, published in the open access journal BMJ Open Respiratory Research.

4 Apr 2023

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targeted therapy lorlatinib is safe and effective in treating high-risk neuroblastoma.

4 Apr 2023

Genetic News and Research

Obesity driven by genetic factors linked to lower risk of cardiovascular disease

Study examines the causal role of insomnia symptoms on 11,409 health related-symptoms

Using brain organoids to test gene therapies for a rare disease in children

IU study sheds new light on the development and treatment of rare form of muscular dystrophy

Understanding how surface factors influence or inhibit biofilm formation in the presence of antibiotics

Promising new combination of drugs identified to treat juvenile myelomonocytic leukemia

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

IU researchers focus on tackling binge and "high-intensity" drinking

New method for lower respiratory tract infection diagnosis in critically ill children

Scientists secure funding for cutting-edge research on age-related macular degeneration

Biological underpinnings of a reproductive disorder caused by mutation of autism gene

Antioxidant supplementation shows potential to improve male fertility

The interaction between white adipose tissue mitochondria and gut microbiota in obesity

CRISPR screens reveal genetic determinants of PARP inhibition in prostate cancer

Healthy sleep pattern may help offset asthma risk regardless of genetic susceptibility

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

New software tool uses genetic data to improve cancer modeling technology

Unique brain proteins may be critical regulators of body weight

Innovative approach to customize treatments for colorectal cancer

Live attenuated nasal vaccine elicits superior immunity to SARS-CoV-2 variants in hamsters

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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