Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Moderate levels of exercise may not be enough to control mild hypertension

Moderate levels of exercise may not be enough to control mild hypertension in men and women over age 55, the age group most at risk of later developing potentially fatal heart failure, a new four-year study reports. The findings by researchers at Johns Hopkins, to be published in the journal Archives of Internal Medicine online April 11, call into question the effectiveness of national guidelines on exercise for lowering blood pressure in older people.

11 Apr 2005

Why different tissues in the human body vary in their susceptibility to "amyloid" diseases

Researchers at The Scripps Research Institute are reporting the results of a recent study that addresses why different tissues in the human body vary in their susceptibility to "amyloid" diseases, which include Alzheimer's disease and a cluster of ailments called the familial amyloidoses.

7 Apr 2005

Kidney transplant can reverse systolic heart failure

Doctors at the University of Maryland Medical Center say that contrary to conventional thinking, a kidney transplant can significantly improve the heart function of people on dialysis with a serious form of heart failure.

6 Apr 2005

New technology to help heart and lung patients awaiting transplants

Promising new technology may extend the life of a failing organ for patients suffering from heart or lung disease while they wait for a donor organ. The use of stem cells may eliminate the need for a transplant and even eradicate heart disease in patients.

6 Apr 2005

Diuretics work better for high blood pressure

Study results by faculty members of the University of Texas School of Public Health at Houston suggests that the older, cheaper diuretics remain the drug of choice for both black and non-black patients in treating high blood pressure and reducing risk of heart disease, and confirms earlier findings that diuretics rather than newer, more expensive drugs such as ACE inhibitors, calcium channel blockers, or beta blockers should be preferred as a first therapy for most patients.

5 Apr 2005

Gene therapy shows effect in heart patients

The first double-blind, placebo-controlled randomized trial of VEGF gene injections into the heart muscle of patients with coronary artery disease with the intention of spurring growth of new blood vessels showed significant effects on heart wall motion, although blood flow was not significantly better in treated patients, according to a new study in the April 5, 2005, issue of the Journal of the American College of Cardiology.

5 Apr 2005

Sildenafil prevents anti-cancer drug induced heart damage

Virginia Commonwealth University researchers have found that the popular impotence drug Viagra prevents damage to the heart from a potent chemotherapeutic agent frequently used in the treatment of breast cancer, leukemia and sarcomas.

5 Apr 2005

U.S. website allows consumers to shop around

The US government launched a new Web site on Friday designed to help consumers shop around when it comes to comparing their local hospitals.

4 Apr 2005

Statins, other cholesterol-depleting agents, may disrupt hypertension from developing

Cholesterol-lowering agents, such as the widely-prescribed statin drugs, and cholesterol-blocking agents may prove to be “novel therapeutic agents to modify cellular calcium that contributes to the development of pulmonary hypertension,” according Hemal H. Patel who lead a multidisciplinary team of researchers at the University of California, San Diego (UCSD).

3 Apr 2005

Discovery could lead to new drug targets for heart disease

Mice with glowing green hearts have yielded the latest clue in the search for molecules involved in structural heart disease. Vanderbilt University Medical Center investigators found that blocking the activity of a single protein, called CaM kinase, in the mouse heart protects against the damaging effects of a heart attack.

30 Mar 2005

Important link between kidney damage and cardiac problems

Scientists have identified an important link between kidney damage and cardiac problems, creating new possibilities for treating the primary cause of death in kidney disease patients.

29 Mar 2005

Herceptin - more powerful treatment for patients with HER-2-positive breast cancer

A new use of the drug Herceptin appears to offer a much more powerful treatment advantage than expected for patients with HER-2-positive breast cancer, say researchers at The University of Texas M. D. Anderson Cancer Center.

29 Mar 2005

Doctors raise concern about heart drug Nesiritide

Doctors raise concern about heart drug. The heart drug Nesiritide (Natrecor) is an FDA-approved drug for the treatment of decompensated heart failure, the most common reason for hospitalization for those over 65 years of age.

22 Mar 2005

Ongoing specialist care can improve heart attack survival

When a good network of care involving access to specialists and family physicians is established, it can significantly improve the number of lives saved from heart disease, especially in rural areas, according to a University of Alberta two-year study.

16 Mar 2005

Questions about validity of HOPE TOO vitamin E study

A study published in the March 16 issue of Journal of the American Medical Association (JAMA) suggesting that a "daily-dose" of vitamin E (400 international units) among high-risk (chronically ill) cardiovascular patient populations is associated with a greater risk of heart failure is being challenged by leading health researchers around the country who claim the study lacks the adequate research and controlled sampling audience to justify this conclusion.

16 Mar 2005

More research on Vitamin E surprises scientists

50 years of research into the supposed benefits of taking vitamin E has extolled its antioxidant potential to offer a variety of potential health benefits, including reducing the risk of Alzheimer's, cancer and heart disease.

15 Mar 2005

Vitamin E may increase heart attack risk - does not prevent cancer

A study by Canadian researchers Eva Lonn, M.D., of the Population Health Research Institute and McMaster University, Hamilton Health Sciences Corporation, Hamilton, Ontario, Canada, and colleagues, has found from examining experimental and epidemiological data, that patients who took vitamin E supplements for 7 years did not significantly reduce their risk of cancer or cardiovascular events and some in fact had an increased risk of heart failure.

15 Mar 2005

Study indicates that vitamin E does not prevent cancer

Patients who took vitamin E supplements for about 7 years did not have their risk of cancer or cardiovascular events significantly reduced, and in fact some had an increased risk of heart failure, according to a study in the March 16 issue of JAMA.

15 Mar 2005

Vasogen granted European patent in chronic heart failure

Vasogen today announced that it has been granted a European patent covering the use of its Celacade technology for the treatment of chronic heart failure, and has completed the registration procedure to bring it fully into force in all the major countries of Europe including the U.K., France, Germany, Spain, Italy, and Sweden.

15 Mar 2005

Only one-third of cardiologists believe racial and ethnic disparities in care occur often in the United States

Only one-third of cardiologists surveyed believe racial and ethnic disparities in care occur often in the United States despite extensive documentation of the problem, according to a survey published in a special disparities issue of Circulation: Journal of the American Heart Association.

15 Mar 2005