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FDA panel favors continued research on novel pain medicine

A panel of experts for the U.S. Food and Drugs Administration (FDA) this Monday recommended that the federal government should allow continued testing of an experimental class of pain drugs for arthritis, despite links to bone decay and joint failure.

13 Mar 2012

MRI reveals microgravity-induced intracranial hypertension in astronauts

Magnetic resonance imaging (MRI) of the eyes and brains of 27 astronauts who have spent prolonged periods of time in space revealed optical abnormalities similar to those that can occur in intracranial hypertension of unknown cause, a potentially serious condition in which pressure builds within the skull.

13 Mar 2012

JAK-STAT inhibitors reverse MS-like disease in mice

A new class of drugs completing clinical trials soon for rheumatoid arthritis should be examined as a treatment for multiple sclerosis, according to the authors of a University of Alabama at Birmingham study published today in the Proceedings of the National Academy of Sciences.

13 Mar 2012

Views on Supreme Court case: Both sides stage assault on the Constitution; Obama overreached; Law provides basic needs

As the date of the high court arguments grows nearer, news outlets have a number of editorials and opinions about the health law case.

13 Mar 2012

Level IIb nodes can be avoided during SND for laryngeal squamous cell carcinoma

Metastasis of tumors to level IIb lymph nodes is rare in patients with laryngeal squamous cell carcinoma (LSCC); this area can be ignored during selective neck dissection (SND) to avoid damaging the spinal accessory nerve (SAN), making this surgery more conservative and minimizing SAN morbidity, according to the March 2012 issue of Otolaryngology-Head and Neck Surgery.

12 Mar 2012

Unknown 'root' extension in hair cells of the inner ear

The hair cells of the inner ear have a previously unknown "root" extension that may allow them to communicate with nerve cells and the brain to regulate sensitivity to sound vibrations and head position, researchers at the University of Illinois at Chicago College of Medicine have discovered. Their finding is reported online in advance of print in the Proceedings of the National Academy of Sciences.

10 Mar 2012

Study uncovers critical process in understanding degeneration of brain cells sensitive to AD

A research group led by Dr. A. Claudio Cuello of McGill University's Faculty of Medicine, Dept. of Pharmacology and Therapeutics, has uncovered a critical process in understanding the degeneration of brain cells sensitive to Alzheimer's disease.

9 Mar 2012

PharmAthene revenue increases to $24.3M for year ended December 31, 2011

PharmAthene, Inc., a biodefense company developing medical countermeasures against biological and chemical threats, today reported its financial and operational results for the year ended December 31, 2011.

9 Mar 2012

Biologists identify how and where the brain processes FM sweeps

In both animals and humans, vocal signals used for communication contain a wide array of different sounds that are determined by the vibrational frequencies of vocal cords. For example, the pitch of someone's voice, and how it changes as they are speaking, depends on a complex series of varying frequencies. Knowing how the brain sorts out these different frequencies-which are called frequency-modulated (FM) sweeps-is believed to be essential to understanding many hearing-related behaviors, like speech.

9 Mar 2012

Heart rate lowering drug may reduce “implicit” racial prejudices: Study

It was found that volunteers given the beta-blocker, used to treat chest pains and lower heart rates, scored lower on a standard psychological test of “implicit” racist attitudes. They appeared to be less racially prejudiced at a subconscious level than another group treated with a “dummy” placebo pill.

8 Mar 2012

Deafness penetrates more rapidly and deeply into the brain than previously thought

Portions of a songbird's brain that control how it sings have been shown to decay within 24 hours of the animal losing its hearing.

8 Mar 2012

Scientists focus on genes linked with autism spectrum disorders

With the "Refrigerator Mother" notion about the cause of autism a distant and discredited memory, scientists are making remarkable progress in untangling the genetic roots of the condition, which affects millions of children and adults, according to an article in the current edition of Chemical & Engineering News. C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society.

8 Mar 2012

Some top researchers no longer think of glaucoma solely as an eye disease

A new paradigm to explain glaucoma is rapidly emerging, and it is generating brain-based treatment advances that may ultimately vanquish the disease known as the "sneak thief of sight." A review now available in Ophthalmology, the journal of the American Academy of Ophthalmology, reports that some top researchers no longer think of glaucoma solely as an eye disease.

8 Mar 2012

New minimally invasive procedure can treat resistant hypertension

A radically different approach to treating high blood pressure - using a minimally invasive procedure- is being evaluated as part of a Pivotal Phase III 90-site national trial that includes The Carl H. and Edyth Lindner Center for Research and Education at The Christ Hospital.

8 Mar 2012

Methodist, UH to improve existing surgical training processes

Measure twice and cut once is a well-known phrase among surgeons, but this is not always what happens. To better prepare new surgeons for the operating room, University of Houston (UH) computer scientists are working with medical researchers at the Methodist Institute for Technology, Innovation and Education (MITIE) to improve existing training processes.

7 Mar 2012

Scientists develop nanocombinatorics for directing stem cell differentiation

Northwestern University scientists have developed a powerful analytical method that they have used to direct stem cell differentiation. Out of millions of possibilities, they rapidly identified the chemical and physical structures that can cue stem cells to become osteocytes, cells found in mature bone.

7 Mar 2012

Scientists identify gene that causes adult-onset primary cervical dystonia

Researchers have identified a gene that causes adult-onset primary cervical dystonia, an often-painful condition in which patients' necks twist involuntarily.

5 Mar 2012

Inhalation of nitric oxide could help improve blood flow to ischemic brain

LMU researchers developed a new strategy for the treatment of stroke, which could help to improve blood flow to ischemic brain. Strokes are due to a localized reduction in the blood supply to the brain, mainly due to the blockage of a vessel by a blood clot.

5 Mar 2012

New tool to map extent of traumatic brain injury

Traumatic brain injury among soldiers, sportsmen and women and accident survivors are common but may go undetected at the time of the event and manifest later in life. Now scientists are testing a tool that lights up the breaks these injuries leave deep in the brain's wiring, much like X-rays show broken bones.

4 Mar 2012

Ion channels assembled in different combinations distinguish temperatures

The winter sun feels welcome, but not so a summer sunburn. Research over the past 20 years has shown that proteins on the surface of nerve cells enable the body to sense several different temperatures. Now scientists have discovered how just a few of these proteins, called ion channels, distinguish perhaps dozens of discrete temperatures, from mildly warm to very hot.

3 Mar 2012