Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Discovery provides new mechanism that could be exploited to create malaria vaccine

Scientists have revealed that immune cells called natural killer (NK) cells may play a key role in ridding the body of malaria-infected blood cells, a study in eLife reports.

27 Jun 2018

Study reveals new way to inhibit capillary leakage in sepsis

Leakage from the blood capillaries is a key mechanism leading to septic shock and multiorgan failure, which affect millions of patients annually worldwide. However, there is no effective way to inhibit the vessel leakiness. A new study by scientists at the University of Helsinki and Wihuri Research Institute demonstrates that vascular leakage can be inhibited by targeting vascular integrins.

25 Jun 2018

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

AbbVie , a research-based global biopharmaceutical company, and Calibr, a nonprofit drug discovery division of Scripps Research, today announced a collaboration to develop T-cell therapies aimed primarily at cancer, including solid tumors.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Minakem's new high-class production facility extends capacity to develop and manufacture HPAPI compounds

Minakem, the CDMO division of Minafin, specialized in custom development and manufacturing of building blocks, GMP intermediates and Active Pharmaceutical Ingredients, today announces it is in the final qualification run to open a new closed-controlled environment high containment production facility in August.

22 Jun 2018

UT Southwestern scientists identify gene mutation linked with perplexing brain condition

Scientists conducting one of the largest full DNA analyses of a rare disease have identified a gene mutation associated with a perplexing brain condition that blinds and paralyzes patients.

20 Jun 2018

Scientists create universal assembly method to enhance cancer therapy and diagnostics

Biophysicists have developed a method for modifying the surface of micro- and nanoparticles — tiny structures measuring between a thousandth and a millionth of a millimeter — by covering them with biological molecules. Engineered in this way, the particles can serve as both therapeutic and diagnostic agents, delivering drugs to cancer cells.

19 Jun 2018

Researchers use droplet-sized 'miniecosystems' to test therapeutic potential of molecules

Scripps Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'miniecosystems' to quickly see if a molecule can function as a potential therapeutic.

19 Jun 2018

Study finds increased risk of mortality in people with cold agglutinin disease in five years after diagnosis

Bioverativ Inc., a Sanofi company dedicated to transforming the lives of people with rare blood disorders, today announced results from a new, population-based retrospective study that found a greater than twofold increased risk of mortality in people with cold agglutinin disease within the first five years after diagnosis.

18 Jun 2018

Innovative drugs and new European treatment guidelines refine, improve MS therapy

MS is the most common neurological disease in young adults. There are about 2.3 million people worldwide who face a high risk of ever worsening disabilities from this disease.

18 Jun 2018

Studies provide insight into molecular changes prior to onset of arthritis

The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) provide insight into molecular changes prior to the onset of arthritis which could inform future novel diagnostics and early therapeutic interventions.

18 Jun 2018

Sleep disorders appear to be first sign of serious neurological diseases

Sleep disorders are often the first sign of serious neurological diseases. Neurologists should inquire extensively about the quality of their patients' sleep.

18 Jun 2018

Zika Virus: What Does the Future Hold?

Following the Zika virus epidemic that swept across Brazil between 2015-2016, Dr. Julia Clarke and her team begun working to establish the long-term effects of Zika, and recently discovered that TNF-a inhibitors can be used to prevent microencephaly.

18 Jun 2018

Study demonstrates increased levels of gum disease in people at risk of rheumatoid arthritis

The results of a study presented at the Annual European Congress of Rheumatology demonstrates increased levels of gum disease, and disease-causing bacteria, in individuals at risk of rheumatoid arthritis.

18 Jun 2018

Canakinumab reduces gout rate by more than half in atherosclerosis patients, study shows

The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate that canakinumab significantly reduced the rate of gout by more than half compared to placebo, regardless of baseline serum urate level.

18 Jun 2018

Study: Allergen in red meat linked to plaque buildup in arteries of the heart

A team of researchers says it has linked sensitivity to an allergen in red meat to the buildup of plaque in the arteries of the heart.

14 Jun 2018

Study finds higher response to anti-PD1 immunotherapy in older melanoma patients

With each decade of life, the likelihood of progression of melanoma after treatment with anti-PD1 immunotherapy decreased by 13 percent.

13 Jun 2018

Older melanoma patients fare better on immune checkpoint blockade therapy

Patient age correlates with response to immunotherapy in melanoma and depleting regulatory T cells in young patients may have a therapeutic potential to enhance response in younger patients, according to research from The Wistar Institute. Study results were published online in Clinical Cancer Research.

13 Jun 2018

Scientists discover protective mechanism against atherosclerosis

Atherosclerosis, the pathological narrowing of blood vessels, is the underlying cause for the majority of strokes and heart attacks, the major causes of mortality worldwide according to the WHO.

12 Jun 2018

AbCellera and Denali collaborate to discover new antibodies to fight neurodegenerative diseases

AbCellera Biologics Inc. today announced the successful completion of the first phase of its collaboration with Denali Therapeutics Inc.

12 Jun 2018

Antibody News and Research

Further Reading

Discovery provides new mechanism that could be exploited to create malaria vaccine

Study reveals new way to inhibit capillary leakage in sepsis

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Minakem's new high-class production facility extends capacity to develop and manufacture HPAPI compounds

UT Southwestern scientists identify gene mutation linked with perplexing brain condition

Scientists create universal assembly method to enhance cancer therapy and diagnostics

Researchers use droplet-sized 'miniecosystems' to test therapeutic potential of molecules

Study finds increased risk of mortality in people with cold agglutinin disease in five years after diagnosis

Innovative drugs and new European treatment guidelines refine, improve MS therapy

Studies provide insight into molecular changes prior to onset of arthritis

Sleep disorders appear to be first sign of serious neurological diseases

Zika Virus: What Does the Future Hold?

Study demonstrates increased levels of gum disease in people at risk of rheumatoid arthritis

Canakinumab reduces gout rate by more than half in atherosclerosis patients, study shows

Study: Allergen in red meat linked to plaque buildup in arteries of the heart

Study finds higher response to anti-PD1 immunotherapy in older melanoma patients

Older melanoma patients fare better on immune checkpoint blockade therapy

Scientists discover protective mechanism against atherosclerosis

AbCellera and Denali collaborate to discover new antibodies to fight neurodegenerative diseases

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