X linked News and Research

RSS

Biological factors, cell behaviour drive tumour growth contributing to therapy failure and relapse

Cancer scientists led by Dr. John Dick at the Princess Margaret Cancer Centre have found a way to follow single tumour cells and observe their growth over time. By using special immune-deficient mice to propagate human colorectal cancer, they found that genetic mutations, regarded by many as the chief suspect driving cancer growth, are only one piece of the puzzle. The team discovered that biological factors and cell behaviour - not only genes - drive tumour growth, contributing to therapy failure and relapse.

14 Dec 2012

Mineral metabolism abnormalities may increase risk of kidney failure among African Americans

Abnormalities of mineral metabolism worsen with progressive chronic kidney disease (CKD) and are linked with a higher risk for kidney failure among African Americans, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

Health systems must be more ‘adherence-friendly’

Heath system strategies must be appropriately designed to help narrow persistent racial/ethnic gaps in the use of antihypertensive therapy, say researchers.

13 Dec 2012

Study focuses on nontraditional lifestyle of Retinoblastoma tumor suppressor proteins

Researchers at Michigan State University have discovered a protein that does its best work with one foot in the grave.

13 Dec 2012

Dantrolene may help combat Duchenne muscular dystrophy in boys

Drugs are currently being tested that show promise in treating patients with Duchenne muscular dystrophy (DMD), an inherited disease that affects about one in 3,600 boys and results in muscle degeneration and, eventually, death.

13 Dec 2012

Study finds many patients with family history of LINE-1 hypomethylated colorectal cancer

When people with a family history of colorectal cancer develop the disease, their tumors often carry a molecular sign that the cancer could be life-threatening and may require aggressive treatment, Dana-Farber Cancer Institute scientists report in a new study.

13 Dec 2012

Drugs that bind to specific serotonin receptors can improve and impair female sexual function

Drugs that bind to specific serotonin receptors in the brain can both improve and impair female sexual function in non-human primates.

12 Dec 2012

Later puberty onset protective against testicular cancer

Males who undergo puberty late appear to have a lower than average risk for developing testicular cancer, report scientists, who emphasize that early puberty is not associated with an increased cancer risk.

12 Dec 2012

Decreased air pollution continues to increase life expectancy in USA

Significant reductions in air pollution over the past decade have improved life expectancy across various US counties, report researchers, although they stress that optimum air quality levels have not yet been reached.

12 Dec 2012

Link between CTNNA3 gene mutations and arrhythmogenic right ventricular cardiomyopathy

Unfortunately, newspaper articles about young athletes dying suddenly on the field are not unheard of. Such reports fuel discussions about compulsory screening, for example of young footballers, for heart failure. Research by scientists from Ghent (VIB/UGent) and Italy will benefit these screening methods.

12 Dec 2012

Contact precautions reduce number of visits by healthcare workers and outside visitors

The prevention and control of healthcare-associated infections (HAIs) can help reduce patient morbidity and mortality, but a common prevention effort for patients with hard to treat infections known as contact precautions, can have positive and negative impacts on patient care.

12 Dec 2012

Cognitive impairments linked to mood episode recurrence risk

Cognitive impairments are associated with an increased risk for mood episode recurrence in euthymic patients with bipolar disorder, researchers report.

11 Dec 2012

Nature, nurture appear to be significant factors in early antisocial behaviors of adopted children

Both nature and nurture appear to be significant factors in early antisocial behaviors of adopted children, a Wayne State University researcher believes.

11 Dec 2012

Pfizer's PD0325901 experimental drug blocks untreatable NF1 tumors

Researchers conducting a preclinical study in mice successfully used targeted molecular therapy to block mostly untreatable nerve tumors that develop in people with the genetic disorder Neurofibromatosis 1 (NF1).

11 Dec 2012

Metformin therapy improves BMI and fasting glucose levels in obese children

Metformin therapy has a beneficial treatment effect over placebo in improving body mass index (BMI) and fasting glucose levels in obese children, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). The study showed reduction in BMI was sustained for six months.

11 Dec 2012

X linked News and Research

Biological factors, cell behaviour drive tumour growth contributing to therapy failure and relapse

Mineral metabolism abnormalities may increase risk of kidney failure among African Americans

Health systems must be more ‘adherence-friendly’

Study focuses on nontraditional lifestyle of Retinoblastoma tumor suppressor proteins

Dantrolene may help combat Duchenne muscular dystrophy in boys

Study finds many patients with family history of LINE-1 hypomethylated colorectal cancer

Drugs that bind to specific serotonin receptors can improve and impair female sexual function

Later puberty onset protective against testicular cancer

Decreased air pollution continues to increase life expectancy in USA

Link between CTNNA3 gene mutations and arrhythmogenic right ventricular cardiomyopathy

Contact precautions reduce number of visits by healthcare workers and outside visitors

Cognitive impairments linked to mood episode recurrence risk

Nature, nurture appear to be significant factors in early antisocial behaviors of adopted children

Pfizer's PD0325901 experimental drug blocks untreatable NF1 tumors

Metformin therapy improves BMI and fasting glucose levels in obese children

Brain scans could help scientists uncover mechanisms underlying mental fatigue

Risk factors revealed for anti-tuberculosis drug hepatotoxicity

Feature stories dealing with fitness, diet, and nutrition

MSKCC establishes new pancreatic cancer research center

Wellcome Trust researchers discover how brain assesses confidence in its decisions

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

Latest News