B Cell News and Research

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Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

Medical school on Cherokee reservation will soon send doctors to tribal, rural areas

Ashton Glover Gatewood decided to give medical school a second try after learning about a new campus designed for Indigenous students like herself.

1 Nov 2023

3D organization of DNA can influence glioblastoma progression, study reveals

A pioneering study at Umeå University, Sweden, has unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumor known as glioblastoma.

1 Nov 2023

From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

In this interview, Jordi Carreras delves into the fascinating world of Cell Painting, a powerful technology gaining momentum in drug discovery. He shares insights into his groundbreaking research, the unique aspects of Phenaros' drug discovery platform, and the synergy between academia and industry.

From ELRIG (UK) Ltd. 1 Nov 2023

UTA biology professor awarded NIH grant for new super-resolution microscope

UTA will soon add a new piece of cutting-edge equipment to its already impressive and growing research armamentarium - a type of super-resolution microscope (SRM) that allows biologists to see structures within a cell in even finer detail.

31 Oct 2023

Researchers harness a combination of lab-grown cells to regenerate damaged heart muscle

Researchers at the University of Wisconsin–Madison and Academia Sinica of Taiwan have harnessed a combination of lab-grown cells to regenerate damaged heart muscle.

31 Oct 2023

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

How next-gen sequencing is changing antibody drug discovery

New study outlines how next-generation sequencing (NGS) and machine-learning methods can revolutionize antibody discovery, particularly against SARS-CoV-2. The research demonstrates that NGS provides greater epitopic and paratopic diversity, enabling more effective identification and prioritization of therapeutic antibodies.

31 Oct 2023

Trastuzumab deruxtecan offers added benefit for patients with HER2-low breast cancer

The antibody-drug conjugate trastuzumab deruxtecan is approved for various therapeutic indications. Since March 2023, it can also be used as monotherapy for the treatment of adults with unresectable or metastatic HER2-low breast cancer who have received prior chemotherapy at this disease stage or developed disease recurrence early after adjuvant chemotherapy.

31 Oct 2023

New AI tool could lead to precision medicine by predicting drug response

An ideal medicine for one person may prove ineffective or harmful for someone else, and predicting who could benefit from a given drug has been difficult.

31 Oct 2023

Sickle cell disease patients willing to accept high risks for gene therapy cure

Individuals living with severe sickle cell disease (SCD) are highly interested in new, potentially curative gene therapy treatments and are willing to accept associated risks for a chance at a cure, according to a study published today in Blood Advances.

31 Oct 2023

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature."

31 Oct 2023

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

The lungs were once at the forefront of SARS-Cov-2 research, but as reports of organ failure and other serious complications poured in, scientists set out to discover how and why the respiratory virus was causing serious damage to the body's major organs, including the lungs.

31 Oct 2023

B Cell News and Research

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Medical school on Cherokee reservation will soon send doctors to tribal, rural areas

3D organization of DNA can influence glioblastoma progression, study reveals

From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

UTA biology professor awarded NIH grant for new super-resolution microscope

Researchers harness a combination of lab-grown cells to regenerate damaged heart muscle

How one gene shakes up our understanding of male infertility

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

How next-gen sequencing is changing antibody drug discovery

Trastuzumab deruxtecan offers added benefit for patients with HER2-low breast cancer

New AI tool could lead to precision medicine by predicting drug response

Sickle cell disease patients willing to accept high risks for gene therapy cure

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

Study reveals direct link between high insulin levels and pancreatic cancer

AI may help identify potential gonorrhea vaccine proteins

Osteoarthritis may be treatable and reversible, new study shows

Using synthetic biology to develop smarter cell therapies for cancer patients

Axon Biology & The Future of Drug Discovery: A Deep Dive with Dr Federico Dajas-Bailador

UniSA seeks public support for vital research on deadly brain cancers

Using single B cell screening to boost antibody discovery eBook

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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