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Expert explains why onions bring tears to your eyes

According to the National Onion Association (yes, that's a thing), approximately 170 countries grow onions, and it's estimated that 9.2 million acres of onions are harvested annually around the world.

21 Jun 2017

Animal model of Gulf War illness hints at possible ways to mitigate symptoms

When hundreds of thousands of American troops deployed to the Persian Gulf in 1990 and 1991 in what is now called the First Gulf War, they were exposed to a variety of chemicals.

20 Jun 2017

Penn study points to novel therapeutic strategy for preventing severe tooth decay in toddlers

Though most tooth decay can be blamed on bacteria, such as Streptococcus mutans, the fungus Candida albicans may be a joint culprit in an alarmingly common form of severe tooth decay affecting toddlers known as early childhood caries.

20 Jun 2017

Study finds vaccine to lower cholesterol levels could also immunize against heart disease

In people with high cholesterol levels, the fat that is built up in the artery walls narrows the arteries causing a condition called atherosclerosis. A study published on 19th June in the European Heart Journal has found the likelihood of a vaccine that can immunize humans having atherosclerosis, subsequent to successful outcomes in a mouse model study. At present, phase I clinical trial has begun in patients to see the possibility of translating the study findings to humans.

20 Jun 2017

IDT introduces novel rhAmp technology for accurate, cost-effective SNP analysis

Reflecting its mission to provide innovative solutions to the genomics community, Integrated DNA Technologies introduces its unique rhAmp™ SNP Genotyping System, enabling researchers to make accurate and confident SNP calls both quickly and cost-effectively.

19 Jun 2017

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Domainex Ltd. expands its partnership with Imperial College London, to discover novel therapies that reduce heart muscle damage during heart attacks. The aim is to discover a drug that inhibits the enzyme MAP4K4, which plays a key role in triggering cell death following a heart attack.

19 Jun 2017

Researchers show effective oral treatment option for patients with rheumatoid arthritis

Patients suffering from rheumatoid arthritis are treated for around six months with the standard anti-rheumatic agent methotrexate, to which many patients respond very well.

19 Jun 2017

Researchers discover broad role for DNA-cutting enzyme in driving abnormal genetic rearrangements

Researchers studying a DNA-cutting enzyme with a crucial role in regulating the structure of genes have discovered a broad role for its cutting activity in driving abnormal genetic rearrangements called translocations that cause cancer, including leukemias and solid tumors.

16 Jun 2017

IU study may explain how Wolbachia bacterium prevents mosquitoes from transmitting deadly diseases

A new study from Indiana University may explain how a bacterium called Wolbachia prevents mosquitoes from transmitting deadly diseases such as dengue fever, West Nile virus and Zika.

16 Jun 2017

Penn/CHOP research helps to better understand cause of pediatric and treatment-related leukemias

Certain pediatric leukemias share a common underlying cause with treatment-related secondary leukemias.

16 Jun 2017

New position paper recommends sex-specific cardiovascular drug dosages for better treatment

Sex-specific cardiovascular drug dosages are needed to reduce adverse reactions in women, according to a position paper from the European Society of Cardiology published today in the June issue of European Heart Journal - Cardiovascular Pharmacotherapy.

15 Jun 2017

Plant compound found to be effective against drug-resistant HIV

A plant found throughout Southeast Asia traditionally used to treat arthritis and rheumatism contains a potent anti-HIV compound more powerful than the drug AZT, according to a new paper published in the Journal of Natural Compounds.

15 Jun 2017

Researchers find molecule that darkens skin without UV exposure and may protect against skin cancer

A study published in the journal Cell on June 13 has found that a class of small molecules can successfully penetrate and darken human skin samples. The drug developed in the laboratory by researchers in Boston also generates protective tans in red-haired mice.

14 Jun 2017

UNC study uncovers crucial function of key enzyme found in virtually all organisms

UNC School of Medicine researchers have cracked a long-standing mystery about an important enzyme found in virtually all organisms other than bacteria.

13 Jun 2017

Scientists create method for mapping genome-wide DNA damage caused by chemical carcinogen

Scientists have known for decades that smoking cigarettes causes DNA damage, which leads to lung cancer. Now, for the first time, UNC School of Medicine scientists created a method for effectively mapping that DNA damage at high resolution across the genome.

13 Jun 2017

Researchers pinpoint sugar modification in cells that spurs spread of skin cancer

A team of researchers has pinpointed a sugar modification in cells that spurs the spread of skin cancer. Its findings, which appear in the latest issue of the journal Cancer Cell, spotlight a target in the battle against melanoma.

13 Jun 2017

Scientists find way to recover protein structure after chemical denaturation

Scientists from ITMO University in Saint Petersburg and Hebrew University in Jerusalem have found a way to recover a protein structure after its chemical denaturation.

9 Jun 2017

Insecticides and chemicals used to combat Zika linked to reduced motor function in infants

A chemical currently being used to ward off mosquitoes carrying the Zika virus and a commonly used insecticide that was threatened with a ban in the United States have been associated with reduced motor function in Chinese infants, a University of Michigan study found.

9 Jun 2017

Researchers define action profile of experimental drug intended to treat chronic pain

At high doses, drug candidate BIA 10-2474 binds not only to the protein that it targets, but to other proteins as well. It thus deactivates proteins that are involved in the metabolism of nerve cells.

9 Jun 2017

Southern Research aims to develop new radiosensitizers that may greatly benefit cancer patients

Two out of three cancer patients are treated with radiation, but the therapy often fails to wipe out the tumor or slow its growth. Southern Research is working to develop a new class of drugs that will help the radiation deliver a more powerful punch to the disease.

9 Jun 2017

Enzyme News and Research

Expert explains why onions bring tears to your eyes

Animal model of Gulf War illness hints at possible ways to mitigate symptoms

Penn study points to novel therapeutic strategy for preventing severe tooth decay in toddlers

Study finds vaccine to lower cholesterol levels could also immunize against heart disease

IDT introduces novel rhAmp technology for accurate, cost-effective SNP analysis

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Researchers show effective oral treatment option for patients with rheumatoid arthritis

Researchers discover broad role for DNA-cutting enzyme in driving abnormal genetic rearrangements

IU study may explain how Wolbachia bacterium prevents mosquitoes from transmitting deadly diseases

Penn/CHOP research helps to better understand cause of pediatric and treatment-related leukemias

New position paper recommends sex-specific cardiovascular drug dosages for better treatment

Plant compound found to be effective against drug-resistant HIV

Researchers find molecule that darkens skin without UV exposure and may protect against skin cancer

UNC study uncovers crucial function of key enzyme found in virtually all organisms

Scientists create method for mapping genome-wide DNA damage caused by chemical carcinogen

Researchers pinpoint sugar modification in cells that spurs spread of skin cancer

Scientists find way to recover protein structure after chemical denaturation

Insecticides and chemicals used to combat Zika linked to reduced motor function in infants

Researchers define action profile of experimental drug intended to treat chronic pain

Southern Research aims to develop new radiosensitizers that may greatly benefit cancer patients

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Advancing degrader and proximity-based drug development

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Evaluating new approaches for rare disease genomics

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