Blood Vessels News and Research

RSS

Peregrine's selective anti-VEGF antibodies shown to be as effective as Avastin

Peregrine Pharmaceuticals has reported that preclinical data presented at the Centennial Annual Meeting of the American Association for Cancer Research (AACR) showed that its monoclonal antibody 2C3, which selectively blocks vascular endothelial growth factor (VEGF) from binding to the second of the two VEGF receptors, demonstrates potent anti-cancer efficacy in a preclinical orthotopic model of pancreatic cancer.

17 Apr 2007

High blood pressure could be a brain problem

Scientists in Britain say the cause of high blood pressure may lie within the brain, rather than with problems relating to the heart, kidneys or blood vessels.

16 Apr 2007

GlaxoSmithKline initiates study of PROMACTA in chronic idiopathic thrombocytopenic purpura

GlaxoSmithKline has announced the initiation of a global, open-label, single group trial that will assess the efficacy, safety and tolerability of PROMACTA (eltrombopag olamine) in patients previously treated for chronic idiopathic thrombocytopenic purpura (ITP).

15 Apr 2007

Genes set scene for metastasis - promote spread of breast cancer to the lungs

Biologists at Memorial Sloan-Kettering Cancer Center (MSKCC) have identified a set of genes expressed in human breast cancer cells that work together to remodel the network of blood vessels at the site of the primary tumor.

12 Apr 2007

Four genes found to drive spread of breast cancer to the lungs

Studies of human tumor cells implanted in mice have shown that the abnormal activation of four genes drives the spread of breast cancer to the lungs.

12 Apr 2007

Report reveals cost of type 2 diabetes complications

A first-of-its-kind report looking at the prevalence and cost of type 2 diabetes complications shows that an estimated three out of five people (57.9 percent) with type 2 diabetes have at least one of the other serious health problems commonly associated with the disease, and that these health problems are taking a heavy financial toll on the United States.

11 Apr 2007

Restless legs syndrome increases risk of cardiovascular disease

People with restless legs syndrome (RLS), especially the elderly, may be at an increased risk of developing cardiovascular disease, according to a study published in the April 10, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology.

10 Apr 2007

Development of magnetic cationic liposomes for targeting tumor microvasculature

A popular way to attack malignant tumors is using cationic liposomes as drug delivery systems.

10 Apr 2007

Heart study observes 20th year in Forsyth County

Because of the 4,035 Forsyth County residents who participated in a long-running study of heart disease risk factors, researchers at Wake Forest University Baptist Medical Center and colleagues have made major findings such as how being overweight is associated with becoming disabled and that passive smoking increases the risk of hardening of the arteries.

9 Apr 2007

Smoke from other people's burning tobacco kills

The debate is over, according to a 2006 surgeon general's report on secondhand smoke.

5 Apr 2007

New hope for emphysema sufferers

Researchers at the University of Pennsylvania School of Medicine are now studying an investigational treatment that may offer a significant new, minimally-invasive option for those suffering from advanced widespread emphysema.

5 Apr 2007

Use of stimulant drugs may be linked to a higher risk for stroke

The use of stimulant drugs, including cocaine and amphetamines, may be linked to a higher risk for stroke, according to a report in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

4 Apr 2007

Leg pain can mean peripheral arterial disease

David Dow thought he was having back problems, and that his legs were hurting as a result. As it turns out, that pain may have saved his life.

4 Apr 2007

TGF-beta found to be a major player in causing bronchopulmonary dysplasia

Researchers from Massachusetts General Hospital, in collaboration with scientists from the Genzyme Corporation, have identified a potential treatment for a chronic lung disease affecting premature infants.

4 Apr 2007

Severe dengue infections may go unrecognized in international travelers

Severe cases of a common travelers' infection may not be recognized if doctors rely on the World Health Organization's (WHO) guidelines for identifying it, according to a new study published in the April 15 issue of The Journal of Infectious Diseases, now available online.

3 Apr 2007

Dual renin system blocking drug combo provides additional blood pressure-lowering effects

A combination of two medicines that act against the effects of the enzyme renin are more effective in lowering blood pressure than either of the medicines alone, according to a study presented today at the American College of Cardiology's 56th Annual Scientific Session.

2 Apr 2007

$Drug that mimics HDL does not reduce risk of death for heart attack patients with refractory shock$

Drug that mimics HDL does not reduce risk of death for heart attack patients with refractory shock

Patients with acute coronary syndromes (ACS), such as heart attack and recent-onset chest pain, remain at considerable risk of experiencing further serious cardiovascular problems despite improvements in care.

2 Apr 2007

Tilarginine does not reduce risk of death after heart attack

The medication tilarginine, a drug that was believed could be beneficial for patients who develop cardiogenic shock (low blood pressure due to impaired cardiac function) after a heart attack, did not reduce the risk of death up to six months after a heart attack, according to a JAMA study published online March 26.

2 Apr 2007

Clinical trial of Ranibizumab for edema of the mAcula in diabetes

The Juvenile Diabetes Research Foundation, the world's largest charitable funder of type 1 diabetes research, announced that the Ranibizumab for Edema of the mAcula in Diabetes Phase 2 Study (READ 2) is now enrolling patients.

2 Apr 2007