Therapy News and Research

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New strategy to grow and measure how tumor organoids respond to therapy

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a new method to bioprint miniature tumor organoids that are designed to mimic the function and architecture of real tumors. The improved process allows researchers to use an advanced imaging method to study and analyze individual organoids in great detail, which can help researchers identify personalized treatments for people with rare or hard-to-treat cancers.

7 Jun 2023

Oral semaglutide outperforms other medications in type 2 diabetes treatment, significantly reducing HbA1c and body weight

Orally administered semaglutide shows significant efficacy in reducing HbA1c and body weight in patients with type 2 diabetes compared to other treatments. The study includes a large number of participants from multiple trials.

7 Jun 2023

New insight from patients on what helps or hinders medication-assisted opioid use disorder treatment

Patients would be more willing to enter medication-assisted treatment for opioid use disorder if existing stigmas were reduced and more accessible payment support was readily available, a West Virginia University study finds.

6 Jun 2023

Low-carb breakfast tames glucose spikes in type 2 diabetes

Low-carbohydrate diet reduces postprandial glucose and glycemic variability in type 2 diabetics as compared to those fed a standard low-fat breakfast.

6 Jun 2023

Leucine deficient diet has antidepressant effects on chronic restraint stress-induced depression-like behaviors

Depression is a leading cause of disability around the world and contributes greatly to the global burden of disease.

6 Jun 2023

New folate-targeting magnetic microrobot system shows great potential in cancer treatment

The limited ability of microrobots to assist drugs in entering cells hinders their therapeutic efficacy. To address this, the cancer-targeting molecule folic acid (FA) was introduced to microrobots to promote drug uptake by cancer cells via receptor-ligand-mediated endocytosis.

6 Jun 2023

Single dose of anti-Müllerian hormone gene therapy can induce long-term contraception in domestic cats

Currently there are no contraceptives capable of producing permanent sterilization in companion animals. Spaying, the surgical removal of the ovaries and uterus, is the most widely used strategy to control unwanted reproduction in female cats.

6 Jun 2023

Therapeutic nanocarriers engineered from adult skin cells show promise for treating lung injury

Therapeutic nanocarriers engineered from adult skin cells can curb inflammation and tissue injury in damaged mouse lungs, new research shows, hinting at the promise of a treatment for lungs severely injured by infection or trauma.

6 Jun 2023

Two studies seek to understand the drivers of chronic and progressive phase of COVID-19

Early studies of COVID-19 focused on the acute phase of the disease. However, attention has now turned to the long-term consequences of the disease, which are also significant causes of morbidity and mortality.

6 Jun 2023

Recovery from addiction is a journey. There’s no one-and-done solution.

The atmosphere inside the Allen House is easygoing as residents circulate freely through the hallways, meet in group sessions, or gather on a large outdoor patio that features a dirt volleyball court with an oversize net.

6 Jun 2023

Is there radiographic evidence of premature brain aging in individuals with type 1 diabetes?

Researchers identified brain regions most affected in middle-aged and older adults with type I diabetes.

6 Jun 2023

How does tirzepatide stimulate insulin secretion?

Tirzepatide, a drug approved for diabetes and on the fast track for approval as a weight loss therapy, works through a unique ability to activate two different mechanisms the body uses to control insulin secretion and energy balance, Duke Health researchers report.

6 Jun 2023

Microparticle-delivered therapy likely to be the first step toward stopping autoimmune diseases

According to the federal government's National Institute of Neurological Disorders and Stroke, nearly 3 million people worldwide - with almost a third in the United States - are living with multiple sclerosis (MS), a disabling neurological disease in which the body's immune system mistakenly attacks nerves feeding information to the central nervous system (the brain and spinal cord). Although rarely fatal, MS can lead to long-term disabilities, and impair movement, muscle control, vision and cognition.

6 Jun 2023

New meta-analysis explores the link between adult alexithymia and all forms of child maltreatment

Have you ever wanted to convey a feeling but just couldn't find the right words? Millions of people struggle with a personality trait known as alexithymia, which means "no words for feelings."

5 Jun 2023

Study assesses the safety, efficacy of using immune checkpoint inhibitors in patients with advanced kidney cancer

Patients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment.

5 Jun 2023

HER2-targeted antibody drug conjugate shows encouraging responses, long-lasting clinical benefit in several tumor types

In a new study of trastuzumab deruxtecan, a HER2-targeted antibody drug conjugate, researchers observed encouraging responses and long-lasting clinical benefit in several tumor types.

5 Jun 2023

Phase III ZUMA-7 trial: Patients with high-risk large B-cell lymphoma lived longer with axi-cel

Patients with early relapsed or refractory large B-cell lymphoma had significantly improved overall survival when treated with the chimeric antigen receptor (CAR) T cell therapy axicabtagene ciloleucel (axi-cel) when compared to the current standard-of-care chemoimmunotherapy, according to results of the Phase III ZUMA-7 trial reported by researchers from The University of Texas MD Anderson Cancer Center.

5 Jun 2023

Researchers test nitroglycerin patch as treatment for menopausal women experiencing hot flashes

Women have long searched for remedies for the bothersome hot flashes that often come with menopause.

5 Jun 2023

Study provides a treasure trove of information on molecular biology of the immune system

Researchers at Sanford Burnham Prebys, collaborating with scientists from Eli Lilly and Company, have revealed the structure and function of a drug called LY3361237, which can reduce the harmful activity of the immune system to help treat autoimmune diseases.

5 Jun 2023

$3.1 million NIH grant helps study how ankle properties change after a stroke

A close look at how the ankle functions after a stroke could ultimately improve the mobility and rehabilitation outcomes for more than 40 million stroke survivors worldwide who experience persistent walking difficulties.

5 Jun 2023

Therapy News and Research

New strategy to grow and measure how tumor organoids respond to therapy

Oral semaglutide outperforms other medications in type 2 diabetes treatment, significantly reducing HbA1c and body weight

New insight from patients on what helps or hinders medication-assisted opioid use disorder treatment

Low-carb breakfast tames glucose spikes in type 2 diabetes

Leucine deficient diet has antidepressant effects on chronic restraint stress-induced depression-like behaviors

New folate-targeting magnetic microrobot system shows great potential in cancer treatment

Single dose of anti-Müllerian hormone gene therapy can induce long-term contraception in domestic cats

Therapeutic nanocarriers engineered from adult skin cells show promise for treating lung injury

Two studies seek to understand the drivers of chronic and progressive phase of COVID-19

Recovery from addiction is a journey. There’s no one-and-done solution.

Is there radiographic evidence of premature brain aging in individuals with type 1 diabetes?

How does tirzepatide stimulate insulin secretion?

Microparticle-delivered therapy likely to be the first step toward stopping autoimmune diseases

New meta-analysis explores the link between adult alexithymia and all forms of child maltreatment

Study assesses the safety, efficacy of using immune checkpoint inhibitors in patients with advanced kidney cancer

HER2-targeted antibody drug conjugate shows encouraging responses, long-lasting clinical benefit in several tumor types

Phase III ZUMA-7 trial: Patients with high-risk large B-cell lymphoma lived longer with axi-cel

Researchers test nitroglycerin patch as treatment for menopausal women experiencing hot flashes

Study provides a treasure trove of information on molecular biology of the immune system

$3.1 million NIH grant helps study how ankle properties change after a stroke

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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