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Data show that HCV genotype-1 infected patients may benefit from faldaprevir

Data show that Boehringer Ingelheim’s second-generation protease inhibitor faldaprevir, when used in combination with pegylated interferon and ribavirin, was effective even with the presence of naturally-occurring mutant variants of the hepatitis C virus, such as the NS3 Q80K polymorphism

16 Dec 2013

Research roundup: Long-term care use varies dramatically by state; health spending slowdown explained

In 2012, about 58,500 paid, regulated long-term care services providers served about 8 million people in the United States. Long-term care services were provided by 4,800 adult day services centers, 12,200 home health agencies, 3,700 hospices, 15,700 nursing homes, and 22,200 assisted living and similar residential care communities. Each day in 2012, there were 273,200 participants enrolled in adult day services centers, 1,383,700 residents in nursing homes, and 713,300 residents in residential care communities; in 2011, about 4,742,500 patients received services from home health agencies, and 1,244,500 patients received services from hospices. Provider sectors differed in ownership, and average size and supply varied by region (Harris-Kojetin et al., 12/12).

16 Dec 2013

Gilead Sciences gets FDA approval for once-daily single tablet HIV-1 regimen Complera

Gilead Sciences, Inc. today announced that the U.S. Food and Drug Administration has approved the single tablet HIV-1 regimen Complera (emtricitabine/rilpivirine/tenofovir disoproxil fumarate) for use in certain virologically-suppressed (HIV RNA <50 copies/mL) adult patients on a stable antiretroviral regimen in order to replace their current antiretroviral treatment regimen. Complera was first approved in 2011 for patients new to therapy and is now one of the most widely-prescribed HIV regimens in the United States.

13 Dec 2013

Indegene’s MCM division launches Brand-Focused Solutions for brand marketing teams

Indegene, a leading provider of R&D, commercial, and marketing solutions to top global pharmaceutical and healthcare organizations, today announced that its Multi-channel Marketing (MCM) division has launched a suite of Brand-Focused Solutions for the brand marketing teams.

13 Dec 2013

Cardiac patients can benefit from home-based high intensity training

Cardiac patients can benefit from home-based high intensity training, even without the support of fancy training equipment or a clinic, new research from the Norwegian University of Science and Technology has shown.

13 Dec 2013

NeuroPace- Responsive Neurostimulation System treatment to be offered at Spectrum Health

Spectrum Health will be the first health system in West Michigan and among the first in the nation to offer treatment with a newly FDA-approved device that uses electric stimulation of the brain for adult epilepsy patients whose seizures have not responded to medication.

13 Dec 2013

Bioethics Commission releases ethical recommendations to manage incidental and secondary findings

Researchers conduct a memory study, scan a participant's brain, and find more than they bargain for: a tumor. What do the researchers owe the participant? What does the participant want to know?

13 Dec 2013

Airway alterations present even in young smokers without COPD

A study has found functional and inflammatory changes in the nasal and lower airways of young, healthy smokers in the absence of pulmonary function decline.

12 Dec 2013

Climate differences drive gene changes, find Virginia Bioinformatics Institute researchers

Interplay between genes and the environment has been pondered at least since the phrase "nature versus nurture" was coined in the mid-1800s.

12 Dec 2013

New algorithm separates signals into individual frequencies using minimal number of samples

The fast Fourier transform, one of the most important algorithms of the 20th century, revolutionized signal processing. The algorithm allowed computers to quickly perform Fourier transforms - fundamental operations that separate signals into their individual frequencies - leading to developments in audio and video engineering and digital data compression.

12 Dec 2013

Study: Girls in single-sex schools feel more pressure to act like "typical girls"

Newspaper headlines worldwide tout the benefits of single-sex schools: Girls 75% more likely to take math if they go to a single-sex private school, Will boys learn better if girls aren't allowed? Single-sex education is best for girls in stereotypically male subjects.

12 Dec 2013

First patient enrolled in Otonomy's pivotal Phase 2b study of OTO-104 for Meniere's disease

Otonomy, Inc., a clinical stage biopharmaceutical company developing innovative therapeutics for diseases and disorders of the inner and middle ear, today announced enrollment of the first patient in its pivotal Phase 2b study of OTO-104 for the reduction of vertigo in patients with unilateral Meniere's disease.

11 Dec 2013

Antibody-toxin compound shows compelling antitumor activity in non-Hodgkin lymphomas patients

A toxin linked to a targeted monoclonal antibody has shown "compelling" antitumor activity in patients with non-Hodgkin lymphomas who were no longer responding to treatment, according to a report from Dana-Farber Cancer Institute.

11 Dec 2013

Endocrinologist suggests parents to check their child's blood sugar more often during holidays

Indulgences abound during the holidays—from family gatherings to parties with friends and even stockings stuffed with goodies from Santa. For children with diabetes, overindulging on the delicacies of the season could result in more than a stomach ache, it could mean a trip to the emergency room.

10 Dec 2013

Biosimulation and epilepsy treatments: an interview with Dr. Serge Bischoff, CEO of Rhenovia and RHENEPI program director

The need for biosimulation is primarily to do with the very high attrition rate in drug development and especially in the development of drugs for the central nervous system.

10 Dec 2013

FoundationOne Heme identifies clinically actionable genomic alterations in multiple myeloma cases

Foundation Medicine today announced new data from a pilot study demonstrating that its fully informative genomic profile for hematologic malignancies, FoundationOne Heme, identified both novel and previously reported clinically actionable genomic alterations in multiple myeloma cases. These data were presented in an oral presentation titled Pilot Study To Evaluate The Prevalence Of Actionable Oncogenic Mutations In Patients With Relapsed Refractory Multiple Myeloma (abstract number 755) by Alexander Lesokhin, M.D., medical oncologist, Memorial Sloan-Kettering Cancer Center, at the 55th American Society of Hematology Annual Meeting in New Orleans.

10 Dec 2013

Researchers use popular music to help severely brain-injured patients recall personal memories

In the first study of its kind, two researchers have used popular music to help severely brain-injured patients recall personal memories. Amee Baird and Séverine Samson outline the results and conclusions of their pioneering research in the recent issue of the journal Neuropsychological Rehabilitation.

10 Dec 2013

Orthogonal design to sift optimal parameter of Neiguan acupuncture

The individual difference and non-repeatability in acupuncture have not only restricted the development of acupuncture, but have also affected the specificity of acupoints.

10 Dec 2013

New findings on effects of epilepsy on mother and child

New research pertaining to the latest findings on the effects of epilepsy on both the mother and child were presented at the American Epilepsy Society's 67th Annual Meeting in Washington DC. These studies explore folic acid use, the effect of surgery with intractable focal epilepsy, and antiepileptic drug exposure during breastfeeding.

10 Dec 2013

Exercise program improves symptoms of depression in patients with Parkinson's disease

A new study by a movement disorder neurologist at The Ohio State University Wexner Medical Center found that depression improved among patients with Parkinson's disease who participated in a long-term group exercise program.

10 Dec 2013

Frequency News and Research

Data show that HCV genotype-1 infected patients may benefit from faldaprevir

Research roundup: Long-term care use varies dramatically by state; health spending slowdown explained

Gilead Sciences gets FDA approval for once-daily single tablet HIV-1 regimen Complera

Indegene’s MCM division launches Brand-Focused Solutions for brand marketing teams

Cardiac patients can benefit from home-based high intensity training

NeuroPace- Responsive Neurostimulation System treatment to be offered at Spectrum Health

Bioethics Commission releases ethical recommendations to manage incidental and secondary findings

Airway alterations present even in young smokers without COPD

Climate differences drive gene changes, find Virginia Bioinformatics Institute researchers

New algorithm separates signals into individual frequencies using minimal number of samples

Study: Girls in single-sex schools feel more pressure to act like "typical girls"

First patient enrolled in Otonomy's pivotal Phase 2b study of OTO-104 for Meniere's disease

Antibody-toxin compound shows compelling antitumor activity in non-Hodgkin lymphomas patients

Endocrinologist suggests parents to check their child's blood sugar more often during holidays

Biosimulation and epilepsy treatments: an interview with Dr. Serge Bischoff, CEO of Rhenovia and RHENEPI program director

FoundationOne Heme identifies clinically actionable genomic alterations in multiple myeloma cases

Researchers use popular music to help severely brain-injured patients recall personal memories

Orthogonal design to sift optimal parameter of Neiguan acupuncture

New findings on effects of epilepsy on mother and child

Exercise program improves symptoms of depression in patients with Parkinson's disease

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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