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High-throughput sequencing can detect early signs of leukemia relapse

A study led by researchers at Fred Hutchinson Cancer Research Center has found that a next-generation, high-speed DNA-decoding technology called high-throughput sequencing can detect the earliest signs of potential relapse in nearly twice the number of leukemia patients as compared to flow cytometry, the current gold standard for detecting minimal residual disease.

17 May 2012

Smartphones can improve QOL for people with poor vision

iPhones and other smartphones can be a huge help to the visually impaired, but few vision doctors are recommending them to patients, according to a study co-authored by a Loyola University Chicago Stritch School of Medicine ophthalmologist.

17 May 2012

Treating prenatal maternal infections could improve birth outcomes, study suggests

Clinical trials are underway to test an azithromycin-based combination treatment for pregnant women, "which could tackle some of the leading preventable causes of death for babies in sub-Saharan Africa," according to researchers from the London School of Hygiene & Tropical Medicine (LSHTM), who published a report on Wednesday in the Journal of the American Medical Association.

17 May 2012

Head impacts may worsen contact sport athletes’ ability to acquire new information

A new study suggests that head impacts experienced during contact sports such as football and hockey may worsen some college athletes' ability to acquire new information. The research is published in the May 16, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

17 May 2012

DSM needs radical change from current ‘field guide’ form

The Diagnostic and Statistical Manual of Mental Disorders (DSM), long the master reference work in psychiatry, is seriously flawed and needs radical change from its current "field guide" form, according to an essay by two Johns Hopkins psychiatrists published in the May 17 issue of the New England Journal of Medicine.

17 May 2012

ACE2 molecule now protects major organs in diabetic patients

ACE2, a molecule that has been shown to prevent damage in the heart, is now proving to be protective of the major organs that are often damaged in diabetic patients.

17 May 2012

Updated results from Amgen’s blinatumomab Phase 2 study on ALL

Amgen today announced updated results from a Phase 2 study that showed treatment with blinatumomab (AMG 103) helped achieve a high-rate of complete response (CR) in 72 percent of adult patients with relapsed or refractory B-precursor acute lymphoblastic leukemia (ALL) treated in the study.

17 May 2012

U.S. HIV assistance through PEPFAR prevented 740,000 deaths between 2004-2008, study shows

"The lives of more than 740,000 people in nine African countries were saved between 2004 and 2008 by the U.S. President's Emergency Plan for AIDS Relief [PEPFAR]," according to a study conducted by Stanford University School of Medicine researchers and published in the Journal of the American Medical Association (JAMA) on Wednesday, HealthDay News reports.

17 May 2012

Viewpoints: Sen. Alexander proposes a Medicaid-school funding swap; Doctors' voices missing in abortion debates

When I was governor of Tennessee in the early 1980s, I traveled to meet with President Ronald Reagan in the Oval Office and offer that Grand Swap: Medicaid for K-12 education. The federal government would take over 100% of Medicaid, the federal health-care program mainly for low-income Americans, and states would assume all responsibility for the nation's 100,000 public schools. Reagan liked the idea, but it went nowhere.

17 May 2012

TJU researchers to investigate Cu-64 imaging agent for prostate cancer

Jefferson's Kimmel Cancer Center and the Department of Radiology at Thomas Jefferson University received a five-year, $2.6 million grant from the National Institutes of Health (NIH) to investigate a potentially revolutionary method that can stage prostate cancers and detect recurrent disease so accurately, it would significantly reduce the number of confirmation biopsies. Such biopsies can be invasive, costly, and often lead to false-positive readings.

17 May 2012

Reformulated anti-HIV gel may be safe for use in both vagina, rectum

A change in the formulation of tenofovir gel, an anti-HIV gel developed for vaginal use, may make it safer to use in the rectum, suggests a study published online this week in the Journal of Antimicrobial Chemotherapy. In laboratory tests of rectal tissue, researchers from the Microbicide Trials Network (MTN) found that the reformulated gel was less harmful to the lining of the rectum than the original vaginal formulation, and just as effective in protecting cells against HIV.

17 May 2012

Biologists engineer algae to produce potential candidates for malarial vaccine

Biologists at the University of California, San Diego have succeeded in engineering algae to produce potential candidates for a vaccine that would prevent transmission of the parasite that causes malaria, an achievement that could pave the way for the development of an inexpensive way to protect billions of people from one of the world's most prevalent and debilitating diseases. Initial proof-of-principle experiments suggest that such a vaccine could prevent malaria transmission.

17 May 2012

No significant differences in absorption between tablet and softgel capsule forms of folic acid

The bioavailability of folic acid does not significantly differ between delivery in standard tablet or softgel capsule forms, according to research published in this month's Journal of the Academy of Nutrition and Dietetics. Folic Acid helps support a women's pregnancy and development of a healthy newborn.

17 May 2012

Early drug and alcohol use associated with lower levels of educational attainment

Researchers have found evidence that early drug and alcohol use is associated with lower levels of educational attainment.

17 May 2012

Combination of daclizumab and vaccine improves survival of breast cancer patients

A team from the Perelman School of Medicine and the Abramson Family Cancer Research Institute at the University of Pennsylvania found that the FDA-approved drug daclizumab improved the survival of breast cancer patients taking a cancer vaccine by 30 percent, compared to those patients not taking daclizumab.

17 May 2012

Stroke survivors from King County to share their stories during EMS Week

Hours, or even minutes, can mean the difference between life and death when someone is having a stroke. As part of Emergency Medical Services (EMS) Week from May 20-26, stroke survivors from King County will share their stories about how quick recognition of stroke symptoms and timely response and treatment through King County EMS helps patients survive and return to full health.

17 May 2012

Lecture discusses how negative emotions fuel cancer formation and metastasis

When it comes to cancer, there are obvious mind-body links. Stress, pessimism and other emotional factors have been proven to play a role, increasing the risk of cancer, metastasis and early mortality. This is a double-whammy for cancer patients, who must overcome anxiety from the moment they are diagnosed. In particular, stress has been shown to depress the immune system, increase inflammation and affect our bodies on the molecular level, even damaging DNA.

17 May 2012

Treatment in hospitals with medical fellowships improves outcome for prostate cancer radical surgery

Patients who undergo radical surgery for prostate cancer may expect better results, on average, if they're treated in accredited teaching hospitals with residency programs, and better still if the hospitals also have medical fellowships, according to a new study by Henry Ford Hospital.

16 May 2012

Some hand function restored in quadriplegic patient with spinal cord injury

Surgeons at Washington University School of Medicine in St. Louis have restored some hand function in a quadriplegic patient with a spinal cord injury at the C7 vertebra, the lowest bone in the neck. Instead of operating on the spine itself, the surgeons rerouted working nerves in the upper arms. These nerves still "talk" to the brain because they attach to the spine above the injury.

16 May 2012

Social networks influence beliefs regarding safety of influenza vaccines

College students' social networks influence their beliefs regarding the safety of influenza vaccines and decisions about vaccination, according to a new study in the Journal of Adolescent Health.

16 May 2012

Medicine News and Research

High-throughput sequencing can detect early signs of leukemia relapse

Smartphones can improve QOL for people with poor vision

Treating prenatal maternal infections could improve birth outcomes, study suggests

Head impacts may worsen contact sport athletes’ ability to acquire new information

DSM needs radical change from current ‘field guide’ form

ACE2 molecule now protects major organs in diabetic patients

Updated results from Amgen’s blinatumomab Phase 2 study on ALL

U.S. HIV assistance through PEPFAR prevented 740,000 deaths between 2004-2008, study shows

Viewpoints: Sen. Alexander proposes a Medicaid-school funding swap; Doctors' voices missing in abortion debates

TJU researchers to investigate Cu-64 imaging agent for prostate cancer

Reformulated anti-HIV gel may be safe for use in both vagina, rectum

Biologists engineer algae to produce potential candidates for malarial vaccine

No significant differences in absorption between tablet and softgel capsule forms of folic acid

Early drug and alcohol use associated with lower levels of educational attainment

Combination of daclizumab and vaccine improves survival of breast cancer patients

Stroke survivors from King County to share their stories during EMS Week

Lecture discusses how negative emotions fuel cancer formation and metastasis

Treatment in hospitals with medical fellowships improves outcome for prostate cancer radical surgery

Some hand function restored in quadriplegic patient with spinal cord injury

Social networks influence beliefs regarding safety of influenza vaccines

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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