Aging News and Research

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As life expectancy rises, healthy aging is more important than ever

Global disease burden is shifting toward aging-related conditions as people live longer, with these diseases now representing the largest expected lifetime health burden for newborns across all income groups. Modeling suggests that reducing aging-related disease could produce unusually large and progressively greater gains in both longevity and healthy life expectancy because improvements in survival and health reinforce one another.

3 Sep 2026

Semaglutide extended lifespan in older female mice, but that was not the only finding

Late-life semaglutide treatment slowed age-related physiological decline, attenuated multiple molecular hallmarks of aging, and extended median lifespan from 742 to 834 days in aged female mice. The drug reproduced many effects of calorie restriction while providing additional benefits in exploratory behavior, spatial memory, and glucose control, suggesting that some effects extend beyond reduced calorie intake alone.

3 Sep 2026

Cancer-fighting T cells need small amounts of ROS to attack tumors, study finds

New research reveals a promising new target for treating cancer by harnessing a type of molecule previously thought to do more harm than good.

3 Sep 2026

Eight-year study reveals how molecular aging scripts differ individually

Aging does not appear to follow the same molecular script for everyone, according to an eight-year study of 335 women.

3 Sep 2026

Brain-protecting immune cells may actually drive Alzheimer's disease

Immune cells that normally protect the body from damage by attacking foreign or infected cells are found in the brains of patients with Alzheimer's disease and related disorders at much higher levels than in healthy brains.

3 Sep 2026

Menopause may start changing the gut years before periods stop

A longitudinal study of 964 women found that blood markers of gut epithelial barrier dysfunction and microbial product translocation began to rise around 2 to 2.5 years before the final menstrual period and remained elevated after menopause. The findings suggest that changes in gut barrier integrity may form part of the biological transition through menopause and could help explain links between menopause, inflammation, and later health outcomes.

2 Sep 2026

Scientists develop lab-grown heart tissue model for heart failure

Scientists study the underlying causes of a disease or test new potential drugs in animal models or cells obtained from human biopsy specimens before clinical trials.

2 Sep 2026

Insilico Medicine releases frontier AI models for drug discovery

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced the release of a series of frontier specialist models for chemistry and biology, trained through its MMAI Gym for Science framework.

2 Sep 2026

Semaglutide extends lifespan and slows physiological aging in healthy mice

A National Institutes of Health (NIH)-funded study has shown that the GLP-1 drug semaglutide extended lifespan in older, healthy mice by tempering the detrimental effects of aging.

2 Sep 2026

Study identifes genetic variants that shape human personality traits

An international consortium of researchers found that more than 1,200 different genetic variants are associated with the Big Five personality traits - and surprisingly, these personality genetics are linked to dozens of life outcomes.

2 Sep 2026

Inconsistent health records limit care and research for menopausal women

More attention than ever is being paid today to midlife women's health, including the menopause transition.

2 Sep 2026

New research visualizes how aerobic exercise alters brain activity patterns

Researchers at AIST, in collaboration with the University of Texas Southwestern Medical Center in the United States, examined changes in brain activity during cognitive tasks before and after acute aerobic exercise in young and older healthy adults.

2 Sep 2026

Radiologist supply fails to keep pace with rising imaging demand

Demand for medical imaging in the U.S. keeps rising, but the number of radiologists available to read those images has barely budged relative to the population, according to a new research study published in the JACR.

2 Sep 2026

Bacterial protein fragment corisin found to drive pulmonary fibrosis

A bacterial protein fragment called corisin drives the process of pulmonary fibrosis by infiltrating and disrupting the cell's quality-control system, researchers at the University of Illinois Urbana-Champaign and Mie University in Japan found in a new study.

2 Sep 2026