Anesthetics News and Research

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Study illuminates the link between cholesterol and Alzheimer's-associated toxic protein clumps

A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer's-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.

13 Aug 2021

Effort to decipher hospital prices yields key finding: don’t try it at home

A federal price transparency rule that took effect this year was supposed to give patients, employers and insurers a clearer picture of the true cost of hospital care.

9 Jul 2021

Local anesthetic procaine inhibits SARS-CoV-2 in vitro

Research has shown that procaine and procaine-hydrochloride can reduce replication of SARS-CoV-2 and influenza A viruses in infected cells and reduce the production of cytokines by the viruses, making them potentially useful for treating COVID-19.

10 Jun 2021

New system can measure propofol concentration in patient's blood during surgery

Anesthesia may be an exact science, but it's not yet fully personalized. Anesthesiologists use a variety of methods to calculate the right dose for a given patient: clinical studies, medical databases and laboratory measurements, for example. However, every individual responds to anesthetics in a different way, and there's no way of knowing what that response will be until the anesthetic is administered.

29 May 2021

Researchers use anesthetics to study reemerging consciousness, cognitive function after anesthesia

Millions of surgical procedures performed each year would not be possible without the aid of general anesthesia, the miraculous medical ability to turn off consciousness in a reversible and controllable way.

27 May 2021

Research provides new insight into anesthesia-associated tau spreading in the brain

During the development and progression of Alzheimer's disease, a protein called tau accumulates and spreads in the brain.

12 May 2021

Research provides deep and detailed look at how common anesthetic causes unconsciousness

In a uniquely deep and detailed look at how the commonly used anesthetic propofol causes unconsciousness, a collaboration of labs at The Picower Institute for Learning and Memory at MIT shows that as the drug takes hold in the brain, a wide swath of regions become coordinated by very slow rhythms that maintain a commensurately languid pace of neural activity.

27 Apr 2021

Breath Analysis: How Could it Improve Healthcare and Diagnosis?

In this interview, News-Medical talks to Santi Dominguez (SD) and Michael Graz (MG), CEOs at Imspex Diagnostics and Imspex Medical respectively, about the role breath analysis has to play in healthcare and diagnosis.

From Imspex Medical 8 Apr 2021

AGA’s new clinical guidelines recommend the use of IGB for obese patients

Obesity is a global pandemic, affecting about 40% of adults in the United States. There is an enormous unmet need for an effective weight-loss solution.

7 Apr 2021

Mice study finds altered brain connectivity after prolonged anesthesia

Prolonged anesthesia, also known as medically induced coma, is a life-saving procedure carried out across the globe on millions of patients in intensive medical care units every year.

17 Feb 2021

Polymer patch provides controlled release of drugs for post-operative pain management

A Duke-led team of scientists has developed a bio-compatible surgical patch that releases non-opioid painkillers directly to the site of a wound for days and then dissolves away.

11 Jan 2021

Epidural analgesia during childbirth does not increase infant's risk of developing autism

The Society for Obstetric Anesthesia and Perinatology,the American Society of Anesthesiologists, the Society for Pediatric Anesthesia the American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine aim to clearly reassure pregnant women that the article "Association Between Epidural Analgesia During Labor and Risk of Autism Spectrum Disorders in Offspring," a new retrospective database study published in JAMA Pediatrics on October 12th, 2020 does not provide credible scientific evidence that labor epidurals for pain relief cause autism.

13 Oct 2020

Researchers study placebo effect in nausea treatment at the molecular level

The molecular bases of the placebo effect are poorly understood. A team led by Ludwig-Maximilians-Universitaet in Munich researcher Karin Meissner has now studied the phenomenon in the context of nausea, and identified specific proteins that correlate with its favorable impact.

28 Sep 2020

Researchers investigate molecular mechanism responsible for hypnotic effects of thalidomide

Thalidomide is a medication with several different effects, one of which is promoting sleep in the context of insomnia.

24 Sep 2020

Novel liver cancer treatment could shrink tumors in a mouse model

Hepatocellular carcinoma is a common liver cancer with poor prognosis. With symptoms not discovered until later stages, it is considered the most fatal malignant liver cancer worldwide.

10 Sep 2020

Combination of gas embolization and chemotherapy can lead to complete tumor regression

Hepatocellular carcinoma is a particularly stubborn form of cancer with few treatments and a high mortality rate.

8 Sep 2020

Study shows how general anesthetic drugs act on the brain receptors

As you drift into unconsciousness before a surgery, general anesthetic drugs flowing through your blood are putting you to sleep by binding mainly to a protein in the brain called the ɣ-aminobutyric acid type A (GABAA) receptor.

3 Sep 2020

Thermo Fisher Scientific launches two breakthrough imaging filters that take cryo-EM to a new level

Thermo Fisher Scientific, the world leader in serving science, today introduced two breakthrough imaging filters, the Thermo Scientific Selectris Imaging Filter and the Thermo Scientific Selectris X Imaging Filter, taking cryo-electron microscopy to a new level, making it possible to view proteins at true atomic resolution.

From Thermo Fisher Scientific Inc. 13 Aug 2020

Updated clinical practice guidelines for managing mucositis published

Updated clinical practice guidelines for managing mucositis, a very common and often debilitating complication of cancer therapy, was recently published in the journal Cancer.

11 Aug 2020

Study solves the longstanding mystery of anesthesia

Surgery would be inconceivable without general anesthesia, so it may come as a surprise that despite its 175-year history of medical use, doctors and scientists have been unable to explain how anesthetics temporarily render patients unconscious.

30 May 2020