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Study reveals how lipids control SH2 domain-mediated cellular protein interactions

Prof. You-Me Kim and her student Dajung Jung at Pohang University of Science and Technology, in collaboration with Prof. Wonhwa Cho's group at the University of Illinois at Chicago, have identified that the majority of human Src homology 2 (SH2) domains not only bind to proteins, but also interact with membrane lipids with high affinity and specificity.

29 Mar 2016

ONR researcher explores how explosive shock waves contribute to traumatic brain injury

Today's warfighters are outfitted with body armor strong enough to withstand shrapnel from a bomb or other explosive device. One debilitating threat from a blast, however, is a force they can't see--the explosive shock wave itself.

24 Feb 2016

Research proposes new contract scheme for flu vaccine distribution

Research co-authored by Fuqiang Zhang, professor of operations and manufacturing management at Washington University in St. Louis' Olin Business School, proposes a new contract scheme for the vaccine supply chain that could reduce patient wait time.

19 Feb 2016

A more effective method for detecting metastatic prostate cancer

Conventional imaging methods have limited sensitivity for detecting metastatic prostate cancer. With appropriate, timely treatment vital to survival and quality of life, better imaging has been an ongoing goal.

28 Jan 2016

Collaborative team to determine mechanisms that cause traumatic brain injuries due to shockwaves

Nearly 300,000 soldiers have returned from service in Iraq and Afghanistan with symptoms of traumatic brain injuries due to blast shockwaves. Such injuries often go untreated because they are undetected by brain scans despite the symptoms' presence.

24 Dec 2015

Complix signs agreement with Selexis to advance production of autoimmune drug candidate CMX-02

Complix NV, a biopharmaceutical company developing a pipeline of transformative protein therapeutics, called Alphabodies, for the treatment of cancer and severe autoimmune diseases, announces that it is advancing the development of CMX-02, a potential treatment of severe autoimmune disease.

14 Dec 2015

Simple self-rating of health accurately predicts susceptibility to common cold

New research from Carnegie Mellon University psychologists shows that a simple self-rating of health accurately predicts susceptibility to the common cold in healthy adults aged 18-55 years. Published in Psychosomatic Medicine, the study - led by CMU's Sheldon Cohen - indicates that low self-rated-health is associated with poorer immune system competence.

10 Nov 2015

Nucala (mepolizumab) approved for treatment of asthma patients

The U.S. Food and Drug Administration today approved Nucala (mepolizumab) for use with other asthma medicines for the maintenance treatment of asthma in patients age 12 years and older. Nucala is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines.

5 Nov 2015

PSMA PET imaging more precise than MR imaging for detection of high-grade prostate cancer lesions

A molecular imaging biomarker is able to detect fast-growing primary prostate cancer and distinguish it from benign prostate lesions, addressing an unmet clinical need. The new research, published in the July 2015 issue of The Journal of Nuclear Medicine, is significant for patients with suspected prostate cancer that has not been confirmed by standard biopsy.

21 Aug 2015

CrystalGenomics signs agreement with Dong-A ST for commercialization of Acelex (polmacoxib) in Korea

CrystalGenomics, Inc. has announced that it has signed a Sales and Marketing Agreement with Dong-A ST Co., Ltd. for the commercialization of Acelex (polmacoxib) in Korea.

13 Aug 2015

Elsevier, NCI implement two-way linking between research articles on ScienceDirect and datasets in caNanoLab

Elsevier, a world-leading provider of scientific, technical and medical information products and services, and the US National Cancer Institute, a world-leading institute for cancer research, today announced that they have implemented two-way linking between research articles on ScienceDirect and datasets stored in NCI's cancer Nanotechnology Laboratory (caNanoLab) data portal.

9 Jul 2015

Researchers develop new implantable drug-delivery system using nanowire

A team of researchers has created a new implantable drug-delivery system using nanowires that can be wirelessly controlled.

24 Jun 2015

Merus and Selexis receive a € 2.1 million grant for single cell line manufacturing of a bispecific antibody combination to treat colorectal cancer

Merus and Selexis will combine their unique and proprietary Oligoclonics® and SUREtechnology™ platforms respectively to develop a product combining two bispecific full length IgG antibodies that simultaneously targets and potently inhibits three receptor tyrosine kinases...

20 May 2015

Risk factors predict geographic atrophy after anti-VEGF treatment of RAP

Researchers have found three factors that could identify which patients with retinal angiomatous proliferation receiving anti-vascular endothelial growth factor treatment are likely to develop geographic atrophy.

19 May 2015

Austrian Centre of Industrial Biotechnology develops method to reduce production costs of valuable drugs

Imagine a loved relative suffering from cancer - and you could not afford a treatment because the drugs are too expensive. The Austrian Centre of Industrial Biotechnology (acib) developed a method with the power to reduce production costs of highly valued drugs significantly.

19 Mar 2015

BeiGene chooses SAFC's CHOZN Platform to support oncology drug development

Sigma-Aldrich Corporation today announced that SAFC Commercial, its custom manufacturing services business unit, has entered a commercial sales and service contract with leading biopharmaceutical company, BeiGene.

11 Mar 2015

Possible therapies to address cognitive symptoms in individuals with schizophrenia

By studying specially bred mice with specific developmental and cognitive traits resembling those seen in schizophrenia, UC San Francisco researchers have provided new evidence that abnormal rhythmic activity in particular brain cells contributes to problems with learning, attention, and decision-making in individuals with that disorder.

6 Mar 2015

Three hospitals jointly accredited as FIFA Medical Centre of Excellence

Three hospitals--Kobe University Hospital, Hyogo Prefectural Rehabilitation Central Hospital, and Meiwa Hospital--were jointly accredited as a Federation Internationale de Football Association Medical Centre of Excellence.

2 Mar 2015

Lintec to commercialize carbon nanotubes developed at UTD

Lintec of America recently announced an exclusive license to commercialize novel fabrication methods for carbon nanotube (CNT) macrostructures, including sheets, yarns and ribbons, developed at the University of Texas at Dallas.

9 Feb 2015

New studies aim to help doctors, patients, and policymakers understand cancer prognosis, survival

Three papers in the survival monograph published by the Journal of the National Cancer Institute, co-authored by Dartmouth's Norris Cotton Cancer Center investigators Steven Woloshin, MD, MS, and Lisa Schwartz, MD, MS, aim to help doctors, patients, and policymakers better understand cancer prognosis and survival.