Eukaryotes News and Research

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Molecular switch regulates autophagy in plants

Autophagy, or "self-eating", is an essential cellular quality control mechanism that clears the cell of protein aggregates and damaged organelles. This mechanism is inactive under normal conditions and only triggered upon persistent cellular stress.

10 Feb 2023

Transcriptomics analysis identifies thousands of viroid-like circular RNA molecules

Metatranscriptomics analysis reveals the existence of over ten thousand viroids and viroid-like RNAs.

1 Feb 2023

Researchers explore the mechanism involved in the living world’s fastest cell movements

Raphidocystis contractilis belongs to Heliozoa, a group of eukaryotes commonly found in fresh, brackish, and sea water.

18 Jan 2023

Researchers identify inhibitors of the SARS-CoV-2 Nsp14 N7-methyltransferase

A recent study identified inhibitors for SARS-CoV-2 non-structural protein 14 (Nsp14).

17 Jan 2023

The loss of epigenetic information accelerates the aging process

A new study in the journal Cell aimed to determine whether epigenetic changes are a cause of mammalian aging.

15 Jan 2023

Study offers novel insights into the elongation dynamics of eukaryotic cells

Life depends on the precise functioning of several proteins synthesized in cells by ribosomes. This diverse set of proteins, known as a proteome, is maintained by the robust translation elongation of amino acid sequences taking place in the ribosomes.

5 Jan 2023

Current research on gut microbial modulation with culinary herbs and spices

An article published in Food Chemistry elaborated on the health benefits of culinary herbs and spices.

5 Jan 2023

Bioinformatics approach for the design of siRNAs against SARS-CoV-2

Scientists have developed a set of siRNAs against SARS-CoV-2 using computational approaches.

14 Dec 2022

The effect of ubiquitination on SARS-CoV-2 infection and patient prognosis

A recent Clinical and Translational Medicine study utilized several published public datasets to evaluate the biological characteristics associated with the ubiquitination of patients infected with SARS-CoV-2.

2 Dec 2022

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

A new study aimed to analyze the molecular interactions between the hCypA protein and the SARS-CoV-2 variants to determine the impact of variants on the blocking and binding potential of the hCypA–S protein complex with the ACE2 receptor.

2 Nov 2022

New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

Researchers uncover a new way the immune system detects coronavirus infection

In a recent study posted to bioRxiv*, researchers in the United States demonstrated that the main protease (Mpro) of coronaviruses (CoVs) activates host inflammasome responses.

27 Sep 2022

Researchers identify universal features shaping organelle gene retention

Mitochondria are compartments – so-called "organelles" -- in our cells that provide the chemical energy supply we need to move, think, and live.

16 Sep 2022

Understanding what happens when two gut microbiomes clash together

Fecal microbiota transplantation (FMT) – the transfer of lower intestinal fluids and microbes from one individual to another – is sometimes used to treat inflammatory gut diseases, including ulcerative colitis and bacterial infections.

15 Sep 2022

Biosynthetic proteins show promise as SARS-CoV-2 antivirals targeting spike protein

Researchers developed an αRep series specific to the RBD of the SARS-CoV-2 S, which could easily adapt to work stably against SARS-CoV-2 variants at a low cost.

8 Sep 2022

NRL fungal experiment to launch as part of NASA's scheduled Artemis I mission

An experiment prepared by the U.S. Naval Research Laboratory (NRL) will launch as part of NASA's scheduled Artemis I mission to orbit the moon Aug. 29.

26 Aug 2022

Discovery may lead to the development of new systems of antifungal drugs

Mycosis is an infectious disease caused by parasitic mold or yeast and treated with an antifungal, a subgroup of antibiotics.

26 Aug 2022

Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

In the beginning, there was boredom. Following the emergence of cellular life on earth, some 3.5 billion years ago, simple cells lacking a nucleus and other detailed internal structure dominated the planet. Matters would remain largely unchanged in terms of evolutionary development in these so-called prokaryotic cells - the bacteria and archaea - for another billion and a half years.

8 Aug 2022

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

5 Aug 2022

Using CRISPR to Lift the Lid on Probiotics

In this interview, we speak to Echo Pan, a Ph.D. student from North Carolina State University about her latest research that used CRISPR to uncover more on probiotics.

26 Jul 2022